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Aspirin paracetamol ester

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Identification
Molecular formula
C17H15NO5
CAS number
19735-84-3
IUPAC name
(4-acetamidophenyl) 2-acetoxybenzoate
State
State

At room temperature, the compound is a solid, typically in the form of a white crystalline powder.

Melting point (Celsius)
160.50
Melting point (Kelvin)
433.65
Boiling point (Celsius)
350.50
Boiling point (Kelvin)
623.65
General information
Molecular weight
313.31g/mol
Molar mass
313.3300g/mol
Density
1.2900g/cm3
Appearence

This compound typically presents as a white crystalline solid, appearing as fine powder or crystalline granules.

Comment on solubility

Solubility of (4-acetamidophenyl) 2-acetoxybenzoate

(4-acetamidophenyl) 2-acetoxybenzoate, a compound formed from the combination of an acetamidophenyl group and an acetoxybenzoate moiety, exhibits interesting solubility characteristics that reflect its complex structure. The solubility of this compound can be influenced by several factors, including:

  • Polarity: The presence of both polar and nonpolar functional groups can lead to solubility in various solvent systems.
  • Hydrogen Bonding: The presence of amide and ether functionalities allows for potential hydrogen bonding interactions, enhancing solubility in polar solvents.
  • pH Sensitivity: The solubility can vary significantly with pH, as the acetamide may have different solubility profiles in acidic versus basic environments.

Generally, compounds similar to (4-acetamidophenyl) 2-acetoxybenzoate are soluble in:

  • Organic solvents: Such as ethanol and dimethyl sulfoxide (DMSO).
  • Moderately polar solvents: Like methanol, which can facilitate dissolution through polar interactions.

However, they might have limited solubility in water, indicating that the solubility behavior is significantly dependent on the solvent environment. Thus, when evaluating the solubility of (4-acetamidophenyl) 2-acetoxybenzoate, one must consider these factors to understand its potential applications and behavior in various chemical contexts.

Interesting facts

Interesting Facts about (4-Acetamidophenyl) 2-Acetoxybenzoate

(4-Acetamidophenyl) 2-acetoxybenzoate, also known as a derivative of acetaminophen, is a fascinating compound in the field of medicinal chemistry. Here are some key insights that highlight its importance:

  • Pharmaceutical Significance: This compound is often studied for its analgesic and anti-inflammatory properties, similar to those of its parent compound, acetaminophen. It plays a critical role in the development of effective pain management therapies.
  • Structure and Reactivity: The presence of acetoxy and acetamido functional groups in its structure contributes to its reactivity and solubility, making it a versatile compound during synthesis and drug formulation.
  • Research Applications: Scientists are exploring its potential as a lead compound for new drugs tailored to combat various pain-related disorders. Ongoing research may lead to derivatives with enhanced efficacy and reduced side effects.
  • Mechanism of Action: Understanding how this compound interacts within biological systems can provide insights into its mechanism of action, particularly its pain-relieving effects and how it can be optimized for better therapeutic outcomes.
  • Chemical Education: For chemistry students, studying (4-acetamidophenyl) 2-acetoxybenzoate offers a practical example of functional group transformations and the synthesis of organic compounds in the laboratory setting.

As a part of the ongoing quest for better pharmaceuticals, this compound exemplifies the intersection of chemistry and medicine, showing how small changes in molecular structure can lead to significant therapeutic advancements.

Synonyms
Benorilate
BENORYLATE
Salipran
Fenasprate
Benoral
Benortan
Benorilato
Fenasparate
Benzoic acid, 2-(acetyloxy)-, 4-(acetylamino)phenyl ester
Aspirin acetaminophen ester
Benorilatum
WIN 11450
Quinexin
Benorilato [Spanish]
4-Acetamidophenyl salicylate acetate
Benorilatum [INN-Latin]
Benorilato [INN-Spanish]
p-Acetamidophenyl acetylsalicylate
p-N-Acetylaminophenylacetylsalicylate
TO 125
CCRIS 1739
2-Acetoxy-4'-(acetamino)phenylbenzoate
4'-(Acetamido)phenyl-2-acetoxybenzoate
UNII-W1QX9DV96G
EINECS 225-674-5
W1QX9DV96G
Benorilate (INN)
Benorilate [INN:BAN:DCF]
BRN 2166628
DTXSID5022649
2-(Acetyloxy)benzoic acid 4-(acetylamino)phenyl ester
BENORYLATE [MI]
BENORILATE [INN]
WIN-11450
BENORILATE [MART.]
BENORILATE [WHO-DD]
DTXCID202649
Salicylic acid, acetate, ester with 4'-hydroxyacetanilide
4-acetamidophenyl 2-(acetyloxy)benzoate
Benorilatum (INN-Latin)
Benorilato (INN-Spanish)
BENORILATE (MART.)
Triadol
4-acetamidophenyl-O-acetylsalicylate
2-acetoxy-4'-acetaminophenylbenzoate
N02BA10
Benzoic acid, 2-(acetyloxy)-, 4-(acetylamino)phenyl ester (9CI)
225-674-5
fejklnwaoxssnr-uhfffaoysa-n
5003-48-5
4-acetamidophenyl 2-acetoxybenzoate
NCGC00167468-01
Benorilate 100 microg/mL in Acetonitrile
4-(Acetylamino)phenyl 2-(acetyloxy)benzoate
CAS-5003-48-5
(4-acetamidophenyl) 2-acetyloxybenzoate
MFCD00864257
Benorilate (Standard)
SCHEMBL25167
2-(acetyloxy)-Benzoicacid 4-(acetylamino)phenylester
CHEMBL162036
CHEBI:135340
BCPP000346
BCP13353
Tox21_112472
s5043
AKOS016010035
Tox21_112472_1
CCG-267615
DB13657
HY-107795R
KS-5206
NCGC00167468-02
AC-12036
AS-13290
BCP0726000190
HY-107795
B4827
CS-0030669
NS00003960
4-(Acetylamino)phenyl 2-(acetyloxy)benzoate #
A18816
D07291
EN300-18124278
Q373243
SR-01000944978
SR-01000944978-1