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Carbofuran

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Identification
Molecular formula
C12H15NO3
CAS number
1563-66-2
IUPAC name
(4-acetamidophenyl) N-methylcarbamate
State
State

Carbofuran is typically found as a solid at room temperature. It is not commonly encountered in its pure form as a liquid or gas under standard conditions.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.00
Boiling point (Celsius)
299.00
Boiling point (Kelvin)
572.00
General information
Molecular weight
221.25g/mol
Molar mass
221.2470g/mol
Density
1.1800g/cm3
Appearence
Carbofuran is a white crystalline solid. It is often encountered in a powder or granule form for agricultural use. The solid is typically free-flowing and may have a slight chemical odor.
Comment on solubility

Solubility of (4-acetamidophenyl) N-methylcarbamate

The solubility of (4-acetamidophenyl) N-methylcarbamate is an intriguing subject as it is influenced by various factors including temperature, pH, and the presence of solvents. This compound typically exhibits the following solubility characteristics:

  • Polar Solvents: It is generally soluble in polar solvents such as water and methanol due to the presence of amide and carbamate functional groups that can engage in hydrogen bonding.
  • Non-Polar Solvents: In contrast, its solubility in non-polar solvents like hexane may be limited, indicating a preference for polar environments.
  • Temperature Dependency: As with many organic compounds, solubility tends to increase with rising temperature, potentially allowing higher concentrations to be achieved in solution.

In summary, the solubility profile of (4-acetamidophenyl) N-methylcarbamate showcases its compatibility with polar solvents, which is vital for its applications in various chemical processes. Understanding these solubility properties enables scientists to optimize conditions for effective use in both laboratory and industrial settings.

Interesting facts

Interesting Facts about (4-acetamidophenyl) N-methylcarbamate

(4-acetamidophenyl) N-methylcarbamate is a notable compound in the realm of organic chemistry, primarily functioning as a type of carbamate. It has garnered attention not only for its synthetic applications but also for its biological significance.

Biological Significance

This compound is often studied due to its potential effects on the human body. Researchers are intrigued by:

  • Anticholinesterase Activity: As a carbamate, it may inhibit the enzyme acetylcholinesterase, which is crucial for breaking down the neurotransmitter acetylcholine. This can enhance cholinergic transmission in the nervous system.
  • Potential Pharmacological Applications: It has been explored for its use in pharmaceuticals, particularly in drug formulations aimed at treating neurodegenerative diseases.

Synthetic Pathways

The synthesis of (4-acetamidophenyl) N-methylcarbamate involves several intriguing steps. Key methods include:

  • Amidation Reactions: The acetamido group provides a reactive site for further modifications, making it an important building block in medicinal chemistry.
  • Carbomoylation: The introduction of the N-methyl carbamate moiety can significantly alter the compound's properties, enhancing its biological activity.

Research Applications

This compound serves as a versatile structure in research labs. It is valuable for:

  • Drug Development: Used as a model compound to understand the structure-activity relationships in drug design.
  • Toxicological Studies: Studies focus on its effects on cholinergic systems, helping assess safety and efficacy in potential therapeutic applications.

In summary, (4-acetamidophenyl) N-methylcarbamate offers an exciting intersection of chemistry and biology, serving as a critical compound for ongoing research in pharmacology and medicinal chemistry. The myriad of applications and the scientific curiosity it inspires highlights the importance of studying such compounds in greater depth.

Synonyms
Stauffer R-10534
ENT 27,480
BRN 2976338
ACETAMIDE, N-(4-(((METHYLAMINO)CARBONYL)OXY)PHENYL)-
AI3-27480
14260-40-3
R-10534
N-(4-(((Methylamino)carbonyl)oxy)phenyl)acetamide
DTXSID60162097
DTXCID3084588
CHEMBL128777