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Aspirin

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Identification
Molecular formula
C9H8O4
CAS number
50-78-2
IUPAC name
4-acetoxybenzoic acid
State
State

At room temperature, aspirin is a solid. It is typically stable under standard conditions used for pharmaceuticals.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
140.00
Boiling point (Kelvin)
413.15
General information
Molecular weight
180.16g/mol
Molar mass
180.1570g/mol
Density
1.4030g/cm3
Appearence

Aspirin appears as a white, crystalline powder or as colorless crystals. It is commonly available in tablet form for medicinal use.

Comment on solubility

Solubility of 4-acetoxybenzoic acid

4-acetoxybenzoic acid, also known as 4-acetylsalicylic acid, has notable characteristics when it comes to its solubility. This compound is classified as a carboxylic acid, leading to various solubility behaviors in different solvents.

Key Points on Solubility:

  • Solvent Compatibility: 4-acetoxybenzoic acid is soluble in polar solvents such as water and alcohols. This solubility is largely influenced by its functional groups.
  • pH Influence: The solubility of this compound can increase in acidic or basic solutions. It may ionize in a basic solution, enhancing its solubility.
  • Temperature Effect: As with many organic compounds, solubility tends to increase with temperature.
  • Crystallization: This compound can crystallize out of solution under certain conditions, which can affect its availability in solutions.

To summarize, 4-acetoxybenzoic acid demonstrates good solubility in various polar solvents, a property that can be manipulated depending on surrounding conditions such as pH and temperature. Understanding these solubility dynamics is crucial for applications in pharmaceutical formulations and chemical synthesis.

Interesting facts

Interesting Facts about 4-Acetoxybenzoic Acid

4-Acetoxybenzoic acid, also known as p-acetoxybenzoic acid, is a fascinating compound belonging to the category of aromatic carboxylic acids. Its structural characteristics and functional groups provide valuable insights into its diverse applications in various fields.

Key Characteristics

  • Functional Groups: This compound features an acetoxy group and a carboxylic acid group, making it a useful precursor in organic synthesis.
  • Source of Derivatives: As a derivative of benzoic acid, 4-acetoxybenzoic acid serves as a building block for a variety of other compounds, fostering creativity in synthetic organic chemistry.

Applications

  • Pharmaceutical Industry: It is employed in the synthesis of drug formulations, highlighting its importance in developing new medications.
  • Biological Activities: Compounds structurally related to 4-acetoxybenzoic acid have exhibited anti-inflammatory and analgesic properties, contributing to research in medicinal chemistry.
  • Industrial Uses: Additionally, it finds utility in the production of dyes and polymers, showcasing its widespread applicability.

Scientific Insights

One intriguing aspect of 4-acetoxybenzoic acid is its propensity to undergo reactions typical of carboxylic acids, such as esterification and amidation. This allows chemists to manipulate its structure into numerous derivatives with enhanced properties.

As noted by chemists, "The beauty of aromatic compounds lies in their ability to blend stability with reactivity," illustrating the dual nature of 4-acetoxybenzoic acid in both stability and potential reactivity.

In conclusion, 4-acetoxybenzoic acid stands as a testament to the intricacies of organic chemistry, revealing pathways to innovative applications while furthering our understanding of aromatic compounds.

Synonyms
4-ACETOXYBENZOIC ACID
2345-34-8
Benzoic acid, 4-(acetyloxy)-
p-Acetoxybenzoic acid
p-Acetyloxybenzoic acid
p-Carboxyphenyl acetate
Benzoic acid, p-hydroxy-, acetate
AI3-20213
NSC 11340
EINECS 219-066-9
219-066-9
4-(Acetyloxy)benzoic acid
4-Carboxyphenyl acetate
4-Acetoxy benzoic acid
p-Hydroxybenzoic acid acetate
MFCD00002540
4-Acetoxy-benzoic acid
5L73XP7H9J
CHEBI:86560
4-acetyloxybenzoic acid
NSC-11340
4-Acetoxybenzoicacid
4-Acetate-benzoic acid
O-Acetyl-p-hydroxybenzoic acid
Benzoic acid, acetate
p-acetoxy benzoic acid
p-acetoxy-benzoic acid
benzoic acid, 4-acetoxy-
bmse010135
UNII-5L73XP7H9J
SCHEMBL40184
4-(Acetyloxy)benzoic acid #
4-Acetoxybenzoic acid, 96%
CHEMBL131987
DTXSID1062334
Acetic Acid 4-Carboxyphenyl Ester
NSC11340
AKOS001407761
CS-W017218
FA61803
PS-6008
AC-13471
SY017854
A0885
NS00027422
EN300-11679
W13458
SR-01000388952
doi:10.14272/GDBUZIKSJGRBJP-UHFFFAOYSA-N.1
SR-01000388952-1
Q27159246
Z57169570
F1565-0130
Acetic acid 4-carboxyphenyl ester;4-Carboxyphenyl acetate