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Dihydrostreptomycin

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Identification
Molecular formula
C21H41N7O12
CAS number
128-46-1
IUPAC name
4-amino-2-[4,6-diamino-3-[3-amino-6-(aminomethyl)-5-hydroxy-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-6-(hydroxymethyl)tetrahydropyran-3,5-diol
State
State

At room temperature, dihydrostreptomycin is a solid substance, often found in a crystalline form useful for precise dosing in medical applications.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
583.59g/mol
Molar mass
583.5910g/mol
Density
1.7500g/cm3
Appearence

Dihydrostreptomycin typically appears as a white to off-white crystalline powder. It is known for its bitter taste and is soluble in water, making it suitable for aqueous pharmaceutical formulations.

Comment on solubility

Solubility of 4-amino-2-[4,6-diamino-3-[3-amino-6-(aminomethyl)-5-hydroxy-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-6-(hydroxymethyl)tetrahydropyran-3,5-diol

The solubility of the compound with the formula C21H41N7O12 can be considered from various perspectives due to its complex structure. Here are some key points regarding its solubility:

  • Polar Characteristics: The presence of numerous functional groups, such as amino (-NH2) and hydroxyl (-OH) groups, suggests that the compound is likely polar.
  • Hydrophilicity: The incorporation of multiple hydroxyl groups typically enhances water solubility, making it more polar and able to interact with water molecules.
  • Hydrophobic Regions: On the other hand, the existence of hydrophobic segments in the structure may counterbalance the hydrophilic nature, potentially rendering the compound sparingly soluble in water.
  • Solvent Dependence: The solubility may vary based on the solvent used. It may dissolve better in polar organic solvents, while its solubility in non-polar solvents is expected to be lower.

As a general rule, compounds with a balance of hydrophilic and hydrophobic characteristics often exhibit unique solubility profiles that can lead to varying degrees of solubility depending on environmental conditions. Thus, it should be noted that experimental data would be essential to fully understand the solubility behavior of this intricate molecular structure.

Interesting facts

Interesting Facts about 4-amino-2-[4,6-diamino-3-[3-amino-6-(aminomethyl)-5-hydroxy-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-6-(hydroxymethyl)tetrahydropyran-3,5-diol

This compound is a fascinating example of complex organic chemistry and represents the intricate structures often encountered in drug design and biochemistry. Here are some notable facts:

  • Structural Diversity: The molecule features a multi-ring structure, showcasing the rich diversity of functional groups, including amino, hydroxy, and ether functionalities.
  • Biological Relevance: Compounds with similar structures are often studied for their potential biological activities, such as antibacterial and antifungal properties.
  • Alcohol and Amino Groups: The presence of both hydroxymethyl and amino groups suggests that this compound may participate in various biochemical processes or exhibit enzyme interactions.
  • Tetrahydropyran Rings: The cyclic nature of the tetrahydropyran groups contributes to the compound's rigidity and influences its interaction with biological targets.
  • Research Applications: Scientists often explore such compounds for synthesis pathways and therapeutic applications, including the development of new pharmaceuticals.

As noted by chemists: "The complexity of organic molecules often reflects their potential utility in medicinal chemistry." Such compounds illustrate how the synthesis and understanding of chemical structures can lead to advances in health and medicine.


Last but not least, studying compounds like this offers a deeper insight into the nature of interactions within biological systems, paving the way for innovations in drug discovery and therapeutic techniques.

Synonyms
Tobracin
NEBRAMYCIN
Tenebrimycin
Tobramaxin
Tobramitsetin
Tobramycetin
Tenemycin
(1S,3R)-4,6-diamino-3-[(2,6-diamino-2,3,6-trideoxy-alpha-L-ribo-hexopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-allopyranoside
Lilly 47663
1173106-27-8
4,6-Diamino-3-[(3-amino-3-deoxyhexopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,3,6-trideoxyhexopyranoside
Nebramycin Factor 6;Deoxykanamycin B
Prestwick_850
Obracine (Salt/Mix)
Distobram (Salt/Mix)
Gernebcin (Salt/Mix)
NSC180514
Prestwick0_000544
Prestwick1_000544
Prestwick2_000544
CHEMBL14440
SPBio_002508
SCHEMBL2736461
SCHEMBL19523571
SCHEMBL20953776
DTXSID90860478
NLVFBUXFDBBNBW-UHFFFAOYSA-N
HMS1569N09
BBL013217
STK182610
AKOS000715235
AKOS022061227
NCGC00263464-02
A 12253A
VS-03710
DB-048307
NS00123790
4-amino-2-[(4,6-diamino-3-{[3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl)oxy]-6-(hydroxymethyl)oxane-3,5-diol
D-Streptamine, O-3-amino-3-deoxy-.alpha.-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1-4)]-2-deoxy-
D-Streptamine, O-3-amino-3-deoxy-.alpha.-D-glucopyranosyl-(1.->.6)-O-[2,6-diamino-2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1.->.4)]-2-deoxy-
D-Streptamine,6-diamino-2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1.fwdarw.4)]-2-deoxy-
O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1-6))-2-deoxy-L-streptamine
O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1.->.4)-O-[2,6-diamino-2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1.->.6)]-2-deoxy-L-streptamine
O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1.fwdarw.4)-O-[2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1.fwdarw.6)]-2-deoxy-L-streptamine
Streptamine, O-3-amino-3-deoxy-.alpha.-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1-6))-2-deoxy-,D-
Streptamine,6-diamino-2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1.fwdarw.6)]-2-deoxy-, D-