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Methylphenidate

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Identification
Molecular formula
C12H19NO
CAS number
298-59-9
IUPAC name
4-amino-2-methyl-4-phenyl-butan-2-ol
State
State

At room temperature, methylphenidate typically exists as a solid. It is stable under standard conditions and is often found in the form of tablets or capsules for medicinal use. In solution, it must be handled with care to maintain its pharmacological properties.

Melting point (Celsius)
77.00
Melting point (Kelvin)
350.15
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.15
General information
Molecular weight
195.27g/mol
Molar mass
195.2650g/mol
Density
1.0198g/cm3
Appearence

Methylphenidate is typically a white to off-white, odorless crystalline powder. It is known for its purity and consistency, which are vital for its effectiveness as a pharmaceutical compound. The compound is usually synthesized under carefully controlled conditions to ensure its structural integrity and efficacy in therapeutic use.

Comment on solubility

Solubility of 4-amino-2-methyl-4-phenyl-butan-2-ol

The solubility characteristics of 4-amino-2-methyl-4-phenyl-butan-2-ol can be intriguing due to its unique structural features, which influence its behavior in various solvents. Here are some key points regarding its solubility:

  • Polar Nature: The presence of an amino group (-NH2) introduces polarity, which enhances solubility in polar solvents such as water.
  • Hydrophobic Interactions: The phenyl group contributes hydrophobic characteristics, possibly limiting its solubility in non-polar solvents.
  • Hydrogen Bonding: The compound can engage in hydrogen bonding due to both the amino group and hydroxyl groups (if present), promoting solubility in alcohols and other hydrogen-bonding solvents.
  • Temperature Dependence: Like many organic compounds, the solubility may increase with temperature, affecting its application in different conditions.

In conclusion, while 4-amino-2-methyl-4-phenyl-butan-2-ol displays promising solubility in polar solvents due to its amino functionality, limitations may arise due to its hydrophobic portions. Understanding these solubility parameters is essential in predicting its behavior and potential applications in various chemical contexts.

Interesting facts

Exploring 4-Amino-2-methyl-4-phenyl-butan-2-ol

4-Amino-2-methyl-4-phenyl-butan-2-ol, often referred to as a member of the beta-amino alcohol family, is a compound of significant interest in both organic chemistry and pharmacology. This compound is characterized by its unique structure which features an amino group and a hydroxyl group, making it a dual-functional molecule.

Key Characteristics

  • Versatile Intermediate: 4-Amino-2-methyl-4-phenyl-butan-2-ol serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of compounds displaying biological activity.
  • Chiral Center: The presence of a chiral center in its structure allows for the production of enantiomers, which can exhibit different biological properties. Thus, studying this compound offers insight into the principles of chirality in medicinal chemistry.
  • Potential Therapeutic Uses: Due to its amino and alcohol functionalities, this compound is also being investigated for possible applications in drug design, particularly in relation to the central nervous system.

As scientists continue to explore the chemical space around beta-amino alcohols, compounds like 4-amino-2-methyl-4-phenyl-butan-2-ol will play an increasing role in understanding how modifications to molecular structures can lead to enhanced bioactivity. Moreover, this highlights a broader principle in chemistry: as Dr. Linus Pauling famously stated, “The best way to have a good idea is to have a lot of ideas.” By investigating various compounds, we can discover innovative applications and improvements in the field.

In conclusion, the study of 4-amino-2-methyl-4-phenyl-butan-2-ol is a fine example of how a single molecular structure can open up a myriad of avenues for exploration and application in the chemical sciences.

Synonyms
4-Amino-2-methyl-4-phenyl-2-butanol
14593-13-6
4-amino-2-methyl-4-phenylbutan-2-ol
BRN 2716923
3-Amino-1,1-dimethyl-3-phenyl-1-propanol
2-BUTANOL, 4-AMINO-2-METHYL-4-PHENYL-
SCHEMBL434164
DTXSID10932727