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4-Amino-2-mercaptobenzoic acid

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Identification
Molecular formula
C7H7NO2S
CAS number
137-14-6
IUPAC name
4-amino-2-sulfanyl-benzoic acid
State
State

At room temperature, 4-Amino-2-mercaptobenzoic acid is a solid compound.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
323.00
Boiling point (Kelvin)
596.15
General information
Molecular weight
169.19g/mol
Molar mass
169.1920g/mol
Density
1.5120g/cm3
Appearence

4-Amino-2-mercaptobenzoic acid typically appears as a light yellow to off-white crystalline powder. It can have a distinct odor characteristic of sulfur-containing compounds due to the presence of the thiol group.

Comment on solubility

Solubility of 4-amino-2-sulfanyl-benzoic acid

The solubility of 4-amino-2-sulfanyl-benzoic acid can be quite intriguing, as it is influenced by various factors including pH, temperature, and the presence of other ions in the solution. Here are some key points regarding its solubility:

  • Aqueous Solubility: This compound tends to be soluble in water due to the presence of both amino and carboxylic acid functional groups which can participate in hydrogen bonding.
  • Effect of pH: The solubility can significantly increase in basic conditions where the carboxylic acid group is deprotonated, leading to the formation of a negatively charged species that is more soluble.
  • Temperature Dependence: Like many organic compounds, increased temperature generally enhances solubility.
  • Interaction with Solvents: 4-amino-2-sulfanyl-benzoic acid may exhibit different solubility patterns in organic solvents versus water, indicating a potential for varied applications in different environments.

In summary, the solubility of 4-amino-2-sulfanyl-benzoic acid is context-dependent, making it a compound of interest for studies related to formulations in pharmaceuticals and possibly in other chemical syntheses.

Interesting facts

Exploring 4-amino-2-sulfanyl-benzoic acid

4-amino-2-sulfanyl-benzoic acid, often abbreviated as ASBA, is a fascinating example of an aromatic amino acid derivative. This compound is notable for its diverse applications and interesting chemical properties, making it a subject of study in both organic chemistry and medicinal research.

Key Characteristics

  • Aromatic Structure: The presence of a benzene ring lends this compound unique stability and reactivity, valued in various synthesis processes.
  • Amino Group: The amino group (-NH2) is crucial for its role in forming peptide bonds, which are fundamental to proteins.
  • Thiol Group: The sulfanyl (or thiol) group (-SH) enhances its potential for biochemical interactions, making it important for enzyme activity.

Applications in Science

This compound has garnered attention in several fields:

  • Pharmaceuticals: 4-amino-2-sulfanyl-benzoic acid has potential applications in drug development, especially in creating compounds that target specific biological mechanisms.
  • Biochemistry: Its ability to interact with certain enzymes positions it as a candidate for research in metabolic pathways.
  • Analytical Chemistry: ASBA can serve as a reagent in various analytical techniques, offering insights into both organic and inorganic substances.

Interesting Quote

As one scientist put it, "The interplay of the functional groups in 4-amino-2-sulfanyl-benzoic acid opens up pathways for innovative drug design." This speaks to the compound's importance in the frontier of chemical research.

Overall, 4-amino-2-sulfanyl-benzoic acid stands as a compelling compound with a rich chemical profile and a range of applications that continue to inspire researchers and scientists alike.

Synonyms
4-amino-2-sulfanylbenzoic acid
78334-06-2
DTXSID00274845
DTXCID60201117
4-Amino-2-mercaptobenzoic acid
Benzoic acid, 4-amino-2-mercapto-
4-azanyl-2-sulfanyl-benzoic acid
4-Amino-2-mercaptobenzoicacid
SCHEMBL10398139
4-amino-2-sulfanyl-benzoic acid
DDA33406
STL301815
AKOS022135658
AT21193
EN300-1709591
D0U