Skip to main content

4-Amino-3-iodobenzoic acid

ADVERTISEMENT
Identification
Molecular formula
C7H6INO2
CAS number
7429-92-7
IUPAC name
4-amino-3-iodo-benzoic acid
State
State

At room temperature, 4-Amino-3-iodobenzoic acid is in a solid state. It features prominently as a crystalline powder, often utilized in approximately room temperature conditions in laboratory settings due to its solid form.

Melting point (Celsius)
288.00
Melting point (Kelvin)
561.15
Boiling point (Celsius)
444.00
Boiling point (Kelvin)
717.15
General information
Molecular weight
263.03g/mol
Molar mass
263.0310g/mol
Density
2.1290g/cm3
Appearence

4-Amino-3-iodobenzoic acid appears as light brown to yellowish crystalline powder. This compound's appearance might slightly vary depending on its purity and the specific conditions, but it is generally characterized by its crystalline solid form.

Comment on solubility

Solubility of 4-amino-3-iodo-benzoic acid

The solubility of 4-amino-3-iodo-benzoic acid (C7H8I1N1O2) can be influenced by several factors, including its molecular structure and the interactions it has with solvents. This compound contains both an amino group (-NH2) and a carboxylic acid group (-COOH), which allows it to engage in hydrogen bonding, enhancing its solubility in polar solvents.

  • Water: Due to the polar nature of its functional groups, 4-amino-3-iodo-benzoic acid is expected to have moderate solubility in water. The carboxyl group contributes to hydrogen bonding with water molecules.
  • Organic Solvents: It may dissolve better in organic solvents such as alcohols and ether, where it can also engage in intermolecular interactions.
  • Temperature: Solubility is typically temperature-dependent; increasing the temperature can enhance the solubility of organic acids like this compound.

In general, while 4-amino-3-iodo-benzoic acid is soluble in polar solvents, it may show limited solubility in non-polar solvents, owing to the presence of its ionic and polar functional groups. Therefore, it is advisable to choose solvents based on the intended application of the compound.

Interesting facts

Interesting Facts about 4-Amino-3-iodo-benzoic Acid

4-Amino-3-iodo-benzoic acid, often abbreviated as AIBA, is a compound that garners attention due to its unique structural features and various applications. Here are some intriguing aspects about this chemical:

  • Structural Composition: This compound features both an amine group and an iodinated aromatic ring. The placement of these functional groups plays a crucial role in its chemical reactivity and interactions.
  • Pharmaceutical Applications: AIBA has found its niche in the pharmaceutical industry, particularly in drug development. Its structural properties can be leveraged to enhance the efficacy of certain treatments, making it a compound of interest in medicinal chemistry.
  • Research Potential: Scientists are exploring the use of AIBA in organic synthesis, especially for creating more complex molecules. The iodo group can serve as a versatile electrophile in various reactions, allowing for innovative chemical transformations.
  • Biological Relevance: Compounds similar to AIBA are studied for their biological activities, including their role as intermediates in the synthesis of bioactive materials. Understanding how such compounds interact with biological systems can have significant implications for drug design.
  • Environmental Considerations: As with many iodinated compounds, there is growing interest in the environmental impact of AIBA. Ensuring safe handling and disposal is crucial, as iodine can have repercussions in certain ecological contexts.

In the words of famous chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." 4-Amino-3-iodo-benzoic acid is an excellent reminder of the beauty and complexity in chemistry, encouraging ongoing exploration and research.

With its diverse applications and intriguing chemical properties, AIBA continues to be a valuable subject for scientific inquiry and innovation.

Synonyms
4-Amino-3-iodobenzoic acid
BENZOIC ACID, 4-AMINO-3-IODO-
NSC 85381
BRN 2207867
DTXSID10175450
3-14-00-01160 (Beilstein Handbook Reference)
DTXCID1097941
630-295-7
2122-63-6
MFCD01660550
4-Amino-3-iodobenzoicacid
NSC85381
WLN: ZR BI DVQ
NCIOpen2_004886
SCHEMBL4801156
CHEMBL3278366
FPLDDZRJTOXFCB-UHFFFAOYSA-N
CL8102
NSC-85381
AKOS005257278
CS-W012469
FA67646
AS-45990
DB-006640
A2873
EN300-181465