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4-Amino-3-methylphenol

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Identification
Molecular formula
C7H9NO
CAS number
2835-95-2
IUPAC name
4-amino-3-methyl-phenol
State
State

At room temperature, 4-Amino-3-methylphenol is typically found in a solid state. It exists as crystalline powder when dry. The compound is stable under recommended storage conditions, although it is best stored in a cool, dry place to prevent degradation.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
297.00
Boiling point (Kelvin)
570.15
General information
Molecular weight
123.15g/mol
Molar mass
123.1540g/mol
Density
1.1509g/cm3
Appearence

4-Amino-3-methylphenol appears as a white to light brown crystalline solid. It is sensitive to air and light, often taking on a darker hue when exposed. This appearance makes it easily identifiable in laboratory settings.

Comment on solubility

Solubility of 4-amino-3-methyl-phenol

4-amino-3-methyl-phenol, commonly known as p-cresol, exhibits distinct solubility characteristics that are important for its usage in various applications. Understanding its solubility can be vital for effective handling and formulation:

  • Solvent Compatibility: This compound is soluble in organic solvents such as ethanol and ether, while its solubility in water is relatively limited.
  • pH Dependency: The solubility of 4-amino-3-methyl-phenol can also be affected by the pH of the solution. As an amine, its protonation state in different pH environments alters its solubility behavior.
  • Temperature Influence: Generally, with increasing temperature, the solubility of organic compounds in solvents tends to increase, and 4-amino-3-methyl-phenol is no exception.

In practical terms, the limited aqueous solubility suggests that considerable care must be taken when formulating with this compound, especially in aqueous systems. Therefore, the knowledge of its solubility profile is not only academic but also essential in applications such as pharmaceuticals and dye production.

Interesting facts

Interesting Facts about 4-amino-3-methyl-phenol

4-amino-3-methyl-phenol, also known as Mequinol, is a fascinating compound that belongs to the class of aromatic amines. Here are some engaging insights about this compound:

  • Structure and Function: 4-amino-3-methyl-phenol has a distinctive structure that features an amino group and a methyl group attached to a phenolic ring. This arrangement gives it unique properties, which make it useful in various applications.
  • Biochemical Role: The compound plays a crucial role in the synthesis of other chemicals and materials. Notably, it serves as an important intermediate in the production of antioxidants and dye-stuffs.
  • Use in Medicine: Mequinol has gained attention for its potential use in dermatology. It is sometimes utilized in topical formulations to treat skin conditions, particularly to reduce hyperpigmentation.
  • Historical Significance: This compound has a notable history in the field of chemistry, being studied for its reaction mechanisms and the ways in which it interacts with other substrates.
  • Environmental Considerations: As with many chemicals, understanding the environmental impact of 4-amino-3-methyl-phenol is essential. Its biodegradability and effects on ecosystems are areas of ongoing research.

Experts in the field often highlight the compound's versatility and its role in advancing chemistry and related disciplines. As stated by one researcher, "The potential applications of 4-amino-3-methyl-phenol are vast, showcasing the interconnectedness of organic chemistry with biotechnology and medicine."

Overall, 4-amino-3-methyl-phenol serves not only as an intriguing study for students and scientists but also as a reminder of the crucial role chemicals play in our daily lives.

Synonyms
4-Amino-3-methylphenol
4-Amino-m-cresol
2835-99-6
Phenol, 4-amino-3-methyl-
4-amino-3-cresol
4-hydroxy-6-methylaniline
3-methyl-p-aminophenol
4-OH-6'-methylalanine
4-Amino-3-methyl phenol
4-hydroxy-6'-methylalanine
EINECS 220-621-2
NSC 72170
UNII-12R07I1K8C
BRN 2078803
CCRIS 8320
DTXSID2049262
CHEBI:55546
AI3-16313
12R07I1K8C
COLOREX 4AMC
JAROCOL 4A3MP
ORISTAR AMPH43
NSC-72170
4A3MP
M-METHYL-P-AMINOPHENOL
DTXCID7029118
4-13-00-01698 (Beilstein Handbook Reference)
4-AMINO-M-CRESOL [INCI]
220-621-2
inchi=1/c7h9no/c1-5-4-6(9)2-3-7(5)8/h2-4,9h,8h2,1h
qgngogoopuykmc-uhfffaoysa-n
4-Hydroxy-2-methylaniline
3-Methyl-4-aminophenol
p-Amino-m-cresol
p-Hydroxy-o-toluidine
2-Methyl-4-hydroxyaniline
2-Amino-5-hydroxytoluene
m-CRESOL, 4-AMINO-
4-Hydroxy-o-toluidine
4-Amino-3-methyl-phenol
MFCD00007871
4-Amino-Meta-Cresol
4amino-m-cresol
NSC72170
WLN: ZR DQ B1
NCIOpen2_000353
SCHEMBL34069
4-hydroxy-2-methylphenylamine
BIDD:GT0474
4-Amino-3-methylphenol, 97%
CHEMBL3092390
Tox21_202910
MSK000395
STL194284
AKOS000345094
AC-1820
CS-W013540
FA33380
NCGC00260456-01
AS-12563
CAS-2835-99-6
DB-011281
A0288
NS00013353
EN300-79071
A23134
F11227
4-Amino-3-methylphenol 100 microg/mL in Acetonitrile
Q27124363
F0001-0896
Z419012258
4-Hydroxy-2-methylaniline;4 -Amino-3-cresol;2-Amino-5-hydroxytoluene