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Phenibut

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Identification
Molecular formula
C10H13NO2
CAS number
1078-21-3
IUPAC name
4-amino-4-phenyl-butanoic acid
State
State
Phenibut is typically a solid at room temperature. It is stable in dry conditions and behaves like other powdered substances.
Melting point (Celsius)
194.00
Melting point (Kelvin)
467.15
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
179.22g/mol
Molar mass
179.2160g/mol
Density
1.1300g/cm3
Appearence

Phenibut is a white crystalline powder. It is often found in its hydrochloride salt form, which is soluble in water, giving it a granular rather than a fluffy appearance.

Comment on solubility

Solubility of 4-amino-4-phenyl-butanoic acid

4-amino-4-phenyl-butanoic acid, also known as Phenylalanine, is an amino acid that displays unique solubility characteristics:

  • Water Solubility: This compound is generally soluble in water due to the presence of both an amino group and a carboxylic acid group, which can form hydrogen bonds with water molecules.
  • Organic Solvents: 4-amino-4-phenyl-butanoic acid is also soluble in polar organic solvents like alcohols, albeit less readily than in water.
  • Temperature Effects: As with many amino acids, solubility in water can increase with temperature, making it easier to dissolve in warmer solutions.
  • pH Influence: The solubility is also affected by the pH of the solution. In more acidic conditions, the carboxyl group may become protonated, affecting overall solubility.

In conclusion, the solubility of 4-amino-4-phenyl-butanoic acid is influenced by factors like temperature, solvent polarity, and pH. Understanding these parameters is critical for applications involving this compound in biochemical and synthetic processes.

Interesting facts

Interesting Facts About 4-amino-4-phenyl-butanoic acid

4-amino-4-phenyl-butanoic acid, often abbreviated as APB, is a fascinating compound with various applications and properties that intrigue chemists and biochemists alike. Here are some key highlights:

  • Structure: This compound features a unique structure derived from the amino acid family, characterized by both an amino group and a phenyl group attached to a butanoic acid backbone. This combination contributes to its intriguing chemical behavior.
  • Biological Importance: 4-amino-4-phenyl-butanoic acid shows promise in the field of neuroscience, particularly as a potential modulator for specific neurotransmitter systems, which may have implications in treating various neurological disorders.
  • Synthesis: The synthesis of APB can be achieved through several pathways, including multi-step organic reactions. One common method involves the alkylation of a phenylalanine derivative, showcasing the versatility required in organic synthesis.
  • Research Applications: Due to its structural features, this compound serves as a valuable tool in drug design and development, assisting scientists in understanding the interaction between drugs and biological systems.
  • Involvement in Metabolic Pathways: As an amino acid derivative, 4-amino-4-phenyl-butanoic acid participates in metabolic processes that may influence cellular functions and signal transduction pathways.
  • Potential as a Therapeutic Agent: Ongoing research is investigating its potential to alleviate certain conditions influenced by neurotransmitter activity, including mood disorders and neurodegenerative diseases.

In summary, 4-amino-4-phenyl-butanoic acid stands out for its intriguing structure and promising applications in both research and medicine. As scientists continue to explore its properties, the compound’s contributions to the understanding of biochemical processes remain invaluable.

Synonyms
4-amino-4-phenylbutanoic acid
1011-60-5
4-Amino-4-phenyl-butyric acid
Benzenebutanoic acid, gamma-amino-
BUTYRIC ACID, 4-AMINO-4-PHENYL-
4-amino-4-phenyl-butanoic acid
(R)-4-Amino-4-phenyl-butyric acid
NSC-230421
gamma-Phenyl GABA
4-Amino-4-phenylbutyric acid
201863-98-1
NSC 230421
BRN 2720548
(S)-4-Amino-4-phenylbutyric acid
MFCD00844723
NSC230421
GBD7C6WGX2
Oprea1_453514
4-amino-4-phenylbutanoicacid
4-14-00-01716 (Beilstein Handbook Reference)
4-Phenyl-4-aminobutyric acid
SCHEMBL372488
4-phenyl-4-aminobutanoic acid
gamma-Aminobenzenebutanoic acid
Benzenebutanoic acid, ?-amino-
DTXSID501307224
butanoic acid, 4-amino-4-phenyl-
gamma-Phenyl-gamma-aminobutyric acid
STL565288
AKOS004119486
AKOS016344083
SB30103
SB35170
SB35171
DB-262893
CS-0249376
EN300-43298
A57089
G63106