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Folic Acid

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Identification
Molecular formula
C19H19N7O6
CAS number
59-30-3
IUPAC name
4-amino-5-[[2-amino-6-[1,2-bis[(2-amino-4-carboxy-butanoyl)oxy]propyl]-5-methyl-8H-pteridin-4-yl]oxy]-5-oxo-pentanoic acid
State
State

At room temperature, folic acid is in a solid state, commonly observed as a crystalline powder.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
441.40g/mol
Molar mass
441.4010g/mol
Density
1.6400g/cm3
Appearence

Folic acid appears as a yellow or orange crystalline powder. It is practically insoluble in water and most organic solvents but slightly soluble in neutral and alkaline solutions.

Comment on solubility

Solubility of 4-amino-5-[[2-amino-6-[1,2-bis[(2-amino-4-carboxy-butanoyl)oxy]propyl]-5-methyl-8H-pteridin-4-yl]oxy]-5-oxo-pentanoic acid (C19H19N7O6)

The solubility characteristics of the compound are influenced by several factors, primarily due to its complex molecular structure and functional groups. Understanding its solubility can be crucial for applications in various fields such as pharmaceuticals and biochemistry.

Factors Affecting Solubility:

  • Polarity: The presence of multiple amine and carboxylic acid groups contributes to the polarity of the compound, likely enhancing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents can increase solubility. The compound’s structure enables potential hydrogen bonding opportunities.
  • pH Dependency: Given that this compound contains acidic functional groups, its solubility may vary with changes in pH, possibly leading to increased solubility in alkaline solutions.

It is important to note that while *solubility* in water may be relatively high due to the presence of hydrophilic groups, the solubility in organic solvents could vary, potentially making it less soluble. As always with chemical compounds, **experimental determination** is the best method for accurately assessing solubility in specific media.

Interesting facts

Interesting Facts about 4-amino-5-[[2-amino-6-[1,2-bis[(2-amino-4-carboxy-butanoyl)oxy]propyl]-5-methyl-8H-pteridin-4-yl]oxy]-5-oxo-pentanoic acid

This compound, with its intricate structure, is a fascinating example of how functional groups can influence biological activity. Here are some key highlights:

  • Biochemical Significance: This compound is an analogue of essential molecules in the purine biosynthesis pathway. Its structure resembles that of certain nucleotides, which are critical for cellular processes.
  • Potential Therapeutic Applications: Due to its structural similarities to known biomolecules, it may serve as a lead compound in the development of drugs targeting various diseases, including those affecting nucleic acid metabolism.
  • Complex Interaction: The presence of multiple amino groups and carboxylic acid functionalities suggest that the compound can engage in various intermolecular interactions, such as hydrogen bonding and electrostatic interactions, enhancing its potential effectiveness in biochemical pathways.
  • Research in Development: Ongoing studies are evaluating its role and effectiveness as a potential therapeutic agent, making it a point of interest for medicinal chemists.
  • In Silico Studies: Advanced computational models are frequently employed to predict the behavior of compounds like this under physiological conditions, aiding in the rational design of more effective drugs.

In summary, 4-amino-5-[[2-amino-6-[1,2-bis[(2-amino-4-carboxy-butanoyl)oxy]propyl]-5-methyl-8H-pteridin-4-yl]oxy]-5-oxo-pentanoic acid offers a wealth of opportunities for scientific exploration due to its structural complexity and potential implications in pharmaceuticals.