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Identification
Molecular formula
C17H26N2O4S
CAS number
None
IUPAC name
4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide
State
State

The compound is typically in a solid state at room temperature, usually found as a powder.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
265.00
Boiling point (Kelvin)
538.15
General information
Molecular weight
368.47g/mol
Molar mass
368.4710g/mol
Density
1.3000g/cm3
Appearence

The compound is typically a crystalline solid, appearing as a white to off-white powder.

Comment on solubility

Solubility of 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide

The solubility of 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide (C17H26N2O4S) is an important characteristic that influences its utility in various applications. Here are key points regarding its solubility:

  • Polarity: The presence of both a sulfonyl group and a methoxy group suggests enhanced polarity, which can increase solubility in polar solvents.
  • Solvent Compatibility: It is likely to be soluble in dimethyl sulfoxide (DMSO) and water, but possibly less soluble in nonpolar solvents like hexane.
  • Hydrogen Bonding: The amino group can engage in hydrogen bonding which often promotes solubility in aqueous environments.
  • Temperature Dependency: Be aware that solubility can vary with temperature—higher temperatures may improve solubility.

In conclusion, while specific solubility data for this compound may vary based on experimental conditions, understanding its structural attributes provides insights into its solubility behavior. Testing under different conditions may yield the most accurate solubility profiles.

Interesting facts

Interesting Facts about 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide

This compound, with its complex structure, holds significant interest in the fields of medicinal chemistry and pharmacology. Its unique molecular composition makes it an intriguing target for research aimed at understanding the interactions between different functional groups and biological systems.

Key Features:

  • Structure Diversity: The combination of an amine, sulfonyl, and methoxy group contributes to its diverse chemical properties, which can affect its pharmacokinetics and mechanism of action.
  • Pyrrolidine Influence: The inclusion of a pyrrolidine ring can enhance the compound's ability to cross biological membranes, thereby increasing its potential efficacy as a therapeutic agent.
  • Potential Applications: Research indicates that compounds with similar structures can exhibit various biological activities, including anti-inflammatory and analgesic properties.

As researchers delve deeper into its potential, this compound stands out as a promising candidate for the development of new drugs. It encapsulates the essence of modern medicinal chemistry, where the exploration of intricate molecular frameworks can lead to advancements in treatment options.

In the words of renowned chemist Marie Curie, “Nothing in life is to be feared, it is only to be understood.” This sentiment perfectly encapsulates the journey of understanding compounds like this one, where every observation can lead to groundbreaking discoveries.

Synonyms
amisulpride
71675-85-9
Aminosultopride
Solian
Deniban
Amisulprida
Amisulpridum
Socian
Amisulpiride
Barhemsys
DAN 2163
Amisulpride [INN]
Sulamid
Sulpitac
APD421
C17H27N3O4S
Amisulpridum [INN-Latin]
Amisulprida [INN-Spanish]
Amisulpride free base
4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
DAN-2163
EINECS 275-831-7
MFCD00866691
Amisulpride (INN)
NSC-760085
DTXSID5042613
UNII-8110R61I4U
CHEBI:64045
APD-421
4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide
4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide
4-amino-N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide
8110R61I4U
(+/-)-AMISULPRIDE
4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
DTXCID3022613
71675-85-9 (free base)
NSC 760085
NCGC00092310-03
Amisulpridum (INN-Latin)
Amisulprida (INN-Spanish)
AMISULPRIDE (MART.)
AMISULPRIDE [MART.]
Benzamide, 4-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-
R-Amisulpride
S-Amisulpride
AMISULPRIDE (EP MONOGRAPH)
AMISULPRIDE [EP MONOGRAPH]
4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide
SMR000449309
Deniban (TN)
CAS-71675-85-9
Solian (TN)
Amisulpride [INN:BAN]
Amisulpride?
Barhemsys (TN)
4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-anisamid
4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide;Aminosultopride;DAN-2163
Amisulpride; 4-Amino-N-[[(2RS)-1-ethylpyrrolidin-2-yl]methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
(S)-Amisulpride?
(+-)-amisulpride
(plusmn)-amisulpride
PS24 - Amisulpride
Amisulpride (Standard)
AMISULPRIDE [MI]
SL-91.1077
SCHEMBL34126
AMISULPRIDE [WHO-DD]
GTPL963
MLS000758258
MLS000759450
MLS001424039
MLS006011769
CHEMBL243712
Amisulpride - Bio-X trade mark
Amisulpride, >=98% (HPLC)
Amisulpride, 1mg/ml in Methanol
BDBM81790
AMISULPRIDE [ORANGE BOOK]
N05AL05
Amisulpride for system suitability
BCPP000404
HMS2051K10
HMS2235M16
HMS3263D07
HMS3268L09
HMS3369K09
HMS3393K10
HMS3413G07
HMS3657E11
HMS3677G07
HMS3713N06
HMS3884A09
Pharmakon1600-01502285
BCP02089
NSC_2159
WCA67590
WCA67592
Tox21_113392
Tox21_501133
HB1879
HY-14545R
NSC760085
STK635172
STL454297
AKOS005567252
Tox21_113392_1
AC-6820
BCP9000294
CCG-100860
CCG-220622
CCG-222437
CS-1791
DB06288
FA17868
LP01133
NC00110
SDCCGSBI-0633795.P001
NCGC00092310-01
NCGC00092310-02
NCGC00092310-04
NCGC00092310-06
NCGC00092310-16
NCGC00261818-01
AS-13890
BA164158
HY-14545
SY052770
Amisulpride 100 microg/mL in Acetonitrile
CAS_71675-85-9
A2450
NS00000416
S1280
SW197490-3
D07310
AB00639933-07
AB00639933-09
AB00639933_10
EN300-18166870
L000106
Q418785
SR-01000759303
SR-01000759303-5
BRD-A60197193-001-05-4
BRD-A60197193-001-13-8
BRD-A60197193-001-14-6
Amisulpride, British Pharmacopoeia (BP) Reference Standard
Amisulpride, European Pharmacopoeia (EP) Reference Standard
4-Amino-N-[(1-ethyl-2-pyrrolidinyl) methyl]-5-(ethylsulfonyl)-2-benzamide
4-amino-5-ethanesulfonyl-n-(1-ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-benzamide
4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulf onyl)-2-benzamide DAN 2163
4-Amino-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)- 2-methoxybenzamide
4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard
275-831-7
4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzenecarboximidic acid