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Melatonin

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Identification
Molecular formula
C13H16N2O2
CAS number
73-31-4
IUPAC name
4-amino-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]butanamide
State
State

At room temperature, melatonin appears as a solid. It is stable under normal conditions but should be kept in a cool, dry place to prevent degradation.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.00
Boiling point (Celsius)
560.00
Boiling point (Kelvin)
833.00
General information
Molecular weight
232.28g/mol
Molar mass
232.2780g/mol
Density
1.1740g/cm3
Appearence

Melatonin is a white to light brown crystalline powder. It is often supplied in a powder form, and it can be processed into tablets or capsules for supplement use.

Comment on solubility

Solubility of 4-amino-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]butanamide

The solubility of 4-amino-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]butanamide is an intriguing aspect of its chemical behavior. This compound exhibits varying solubility characteristics depending on the solvent used. Here are some key points:

  • Aqueous Solubility: The presence of an amino group contributes to the potential for hydrogen bonding, enhancing solubility in water to some extent.
  • Solvent Influence: Polar solvents may solvate the compound better due to the functional groups present. Conversely, non-polar solvents are likely to result in poor solubility.
  • Temperature Dependence: As with many compounds, solubility could increase with temperature; thus, warm water or solvents may dissolve more of the compound.
  • pH Considerations: The solubility might be affected by the pH of the solution, as it can influence the protonation state of the amino group.
  • Overall Behavior: While the chemical structure indicates a possibility for moderate solubility in polar solvents, precise solubility data should be obtained experimentally for accurate assessments.

In summary, the solubility of 4-amino-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]butanamide is influenced by various factors including solvent type, temperature, and pH, making it essential to consider these elements when evaluating its behavior in different environments.

Interesting facts

Interesting Facts about 4-amino-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]butanamide

4-amino-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]butanamide is a fascinating compound that has garnered attention in the field of medicinal chemistry due to its structural characteristics and potential biological activities. Here are some noteworthy points about this intriguing molecule:

  • Structural Complexity: The compound features an indole ring system, a common structure in many biologically active molecules, which adds to its pharmacological relevance.
  • Biodiversity Connection: The 5-methoxy substitution positions it within a class of compounds that are often found in various plant sources, illustrating nature's ability to inspire synthetic chemistry.
  • Potential Therapeutic Uses: There is ongoing research investigating the compound’s potential as a therapeutic agent, particularly in relation to neurological disorders and as a modulator of neurotransmitter systems.
  • Amino Group Influence: The presence of the amino group demonstrates the compound’s ability to participate in hydrogen bonding, which can significantly influence its interaction with biological targets.

This compound encapsulates a rich tapestry of medicinal chemistry principles, bridging natural product chemistry and synthetic design. According to one renowned chemist, “The beauty of compounds like this lies in their ability to mimic biological pathways, unlocking new avenues for drug discovery.” Such insights make studying compounds like 4-amino-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]butanamide not only scientifically fulfilling but also deeply rewarding in the quest for innovative therapeutic solutions.