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Piritrexim

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Identification
Molecular formula
C19H23N7O3
CAS number
72736-98-4
IUPAC name
4-amino-N-(2-methoxyethyl)-7-(2-methoxyethylamino)-2-phenyl-pteridine-6-carboxamide
State
State

At room temperature, Piritrexim is present as a solid. It is commonly stored in a dry place to preserve its integrity and prevent any unwanted reactions with moisture or other environmental factors.

Melting point (Celsius)
252.00
Melting point (Kelvin)
525.15
Boiling point (Celsius)
610.70
Boiling point (Kelvin)
883.90
General information
Molecular weight
399.43g/mol
Molar mass
399.4330g/mol
Density
1.4300g/cm3
Appearence

Piritrexim is typically a yellow crystalline solid. It is not hygroscopic and remains stable under normal conditions. Its crystalline nature can be seen under microscopic examination, revealing its distinct structural composition.

Comment on solubility

Solubility of 4-amino-N-(2-methoxyethyl)-7-(2-methoxyethylamino)-2-phenyl-pteridine-6-carboxamide

The solubility of 4-amino-N-(2-methoxyethyl)-7-(2-methoxyethylamino)-2-phenyl-pteridine-6-carboxamide can be understood from several perspectives. This compound is characterized by its multiple functional groups, which can influence how easily it dissolves in various solvents.

Factors Affecting Solubility

  • Polarity: Due to the presence of amine and carboxamide groups, the compound exhibits a certain degree of polarity. This may enhance its solubility in polar solvents like water.
  • Hydrophobicity: The phenyl group introduces hydrophobic characteristics, which might decrease solubility in highly polar environments.
  • Solvent Interaction: The presence of methoxyethyl groups adds to nonpolar character, suggesting that mild organic solvents or mixed solvent systems could facilitate better solubility.

In general, it can be stated that:

  1. The compound may be more soluble in organic solvents than in water due to its hydrophobic properties.
  2. It may demonstrate varied solubility depending on temperature and the specific solvent mixture used.

In summary, while 4-amino-N-(2-methoxyethyl)-7-(2-methoxyethylamino)-2-phenyl-pteridine-6-carboxamide is expected to have reasonable solubility in various polar and non-polar solvents, the precise solubility characteristics would need to be determined experimentally.

Interesting facts

Interesting Facts about 4-amino-N-(2-methoxyethyl)-7-(2-methoxyethylamino)-2-phenyl-pteridine-6-carboxamide

This compound is a fascinating member of the pteridine family, known for its diverse biological activities. Pteridines themselves are heterocyclic compounds that often play crucial roles in *biochemistry*, especially in the synthesis of important biomolecules such as vitamins and nucleotides.

Key Features

  • Pharmacological Potential: This compound has been studied for its potential as a pharmacological agent, particularly in the context of cancer research and treatment. Its specific structure allows it to interact with biological systems in unique ways.
  • Structural Complexity: The presence of multiple methoxyethyl groups enhances its solubility, making it easier to work with in laboratory settings.
  • Enzyme Inhibition: Compounds with similar pteridine frameworks have been observed to inhibit key enzymes, which could lead to therapeutic applications in the field of *medicine*.
  • Synthetic Pathways: The synthesis of this compound showcases the creative synthetic strategies employed by chemists, often requiring several multi-step procedures that highlight the importance of *organic synthesis* in drug development.

Moreover, this compound’s structure is a testament to the intricacy of organic chemistry, demonstrating how the arrangement of functional groups can significantly affect biological activity. As a part of ongoing research, it provides insights into how we can design more effective drugs by manipulating molecular characteristics. As Benjamin Franklin once stated, "An investment in knowledge always pays the best interest." The study of such compounds indeed showcases the rich dividends in the field of pharmaceutical science.

In conclusion, 4-amino-N-(2-methoxyethyl)-7-(2-methoxyethylamino)-2-phenyl-pteridine-6-carboxamide represents not only a potential **therapeutic agent** but also a remarkable example of the synergy between organic chemistry and drug design.

Synonyms
WY 5256
BRN 0861724
6-Pteridinecarboxamide, 4-amino-N-(2-methoxyethyl)-7-((2-methoxyethyl)amino)-2-phenyl-
DTXSID30215362
4-Amino-7-(2-methoxyethylamino)-N-(2-methoxyethyl)-2-phenyl-6-pteridine-carboxamide
6-Pteridinecarboxamide, 4-amino-N-(2-methoxyethyl)-7-[(2-methoxyethyl)amino]-2-phenyl-
DTXCID30137853
6504-77-4
4-amino-N-(2-methoxyethyl)-7-(2-methoxyethylamino)-2-phenylpteridine-6-carboxamide
5D6DT49DP9
4-Amino-7-(2-methoxyethylamino)-N-(2-methoxyethyl)-2-phenyl-6-pteridinecarboxamide
4-Amino-N-(2-methoxyethyl)-7-(2-methoxyethylamino)-2-phenyl-6-pteridinecarboxamide