Interesting facts
Interesting Facts about 4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide is a fascinating compound that exemplifies the complexity of modern medicinal chemistry. As an organic molecule, it belongs to the sulfonamide class of drugs, which have a significant role in therapeutic applications, particularly in the field of antibiotics. Here are some interesting aspects:
- Structural Diversity: The compound features a unique combination of a sulfonamide group and an aromatic amine, allowing for diverse interactions within biological systems. The presence of the pyrazine and methoxy groups adds to its structural complexity and potential biological activity.
- Role in Drug Design: Sulfonamides are essential in the development of various pharmaceuticals. This compound can serve as a template for creating novel drugs that target infectious diseases, showcasing the importance of structural modifications in enhancing the efficacy and selectivity of drug candidates.
- Biological Activity: The 3-methoxypyrazin-2-yl moiety is known for its potential antimicrobial properties. Understanding how this functional group affects the overall potency of the compound can be crucial for medicinal chemistry research.
- Research Potential: Ongoing studies involving this compound can lead to insights into structure-activity relationships (SAR) that are fundamental in medicinal chemistry. The compound's unique features may inspire new therapeutic strategies against resistant pathogens.
- Historical Significance: The class of sulfonamides has its roots dating back to the early 20th century, marking a notable milestone in the development of synthetic antibiotics. Compounds like 4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide continue to build upon this legacy, emphasizing the importance of innovation in drug development.
Overall, this compound not only highlights the intricate nature of organic chemistry but also underscores the dynamic intersection between chemistry and medicine. As research progresses, the insights gathered from studying such compounds may lead to groundbreaking advancements in healthcare.
Synonyms
SULFALENE
152-47-6
Sulfamethoxypyrazine
Sulfametopyrazine
Sulfamethopyrazine
4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
Sulfalen
Kelfizine
Kelfizina
Dalysep
Kelfizin
Sulfapyrazinemethoxine
Sulfapyrazinemethoxyne
Sulfapyrazinemethoxyine
Kelfizine W
3-Methoxy-2-sulfapyrazine
Farmitalia 204/122
2-Sulfanilamido-3-methoxypyrazine
3-Methoxy-2-sulfanilamidopyrazine
3-Methoxypyrazine sulfanilamide
Sulfaleno
2-Methoxy-3-sulfanilamidopyrazine
Sulfalene [USAN:INN]
SMP2
Sulfalenum [INN-Latin]
NSC-110433
Sulfaleno [INN-Spanish]
N1-(3-Methoxypyrazinyl)sulfanilamide
Benzenesulfonamide, 4-amino-N-(3-methoxypyrazinyl)-
2-Sulfanilamide 3-methoxy-pyrazine
2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine
2-(p-Aminobenzenesulfonamido)-3-methoxypyrazine
AS 18908
F.I. 5978
Pyrazine, 2-sulfanilamido-3-methoxy-
Kelfizina (TN)
Sulfalene (USAN)
N1-(3-Methoxy-2-pyrazinyl)sulfanilamide
4-Amino-N-(3-methoxypyrazinyl)benzenesulfonamide
N(sup1)-(3-Methoxypyrazinyl)sulfanilamide
N(sup 1)-(3-Methoxypyrazinyl)sulfanilamide
Vetkelfizina
Policydal
N(sup1)-(3-Methoxy-2-pyrazinyl)sulfanilamide
FI 5978
WR 4629
N(sup 1)-(3-Methoxy-2-pyrazinyl)sulfanilamide
Sulfamethopyrazine (JAN)
AS-18908
Sulfanilamide, N'-(3-methoxypyrazinyl)-
Sulfanilamide, N1-(3-methoxypyrazinyl)-
UNII-T6BL4ZC15G
EINECS 205-804-7
NSC 110433
Sulfanilamide, N(sup 1)-(3-methoxypyrazinyl)-
BRN 0622512
DTXSID2046179
Sulfanilamide, N(sup 1)-(3-methoxy-2-pyrazinyl)-
SULFALENE [INN]
SULFALENE [MI]
SULFALENE [USAN]
NSC110433
SULFALENE [WHO-DD]
T6BL4ZC15G
Sulfametopyrazine;AS-18908
4-amino-N-(3-methoxypyrazin-2-yl)benzene-1-sulfonamide
Sulfalenum
SULFAMETHOPYRAZINE [JAN]
DTXCID0026179
CHEBI:32162
SULFAMETOPYRAZINE [MART.]
Solfametopirazina
5-25-12-00574 (Beilstein Handbook Reference)
Solfametopirazina [DCIT]
NCGC00160482-01
Sulphalene
Sulfalenum (INN-Latin)
Sulfaleno (INN-Spanish)
Sulfanilamide, N1-(3-methoxy-2-pyrazinyl)-
Sulphametopyrazine
Sulfametoxypyridazin
Sulfamethoxysuccinate
Sulfapyrazinmethoxine
4-Amino-N-(3-methoxy-pyrazin-2-yl)-benzenesulfonamide
SULFAMETOPYRAZINE (MART.)
CAS-152-47-6
SMR000011031
4-Amino-N-(3-methoxy-2-pyrazinyl)-benzenesulfonamide
CBMicro_013257
ulfalene
Sulfalene(SMPZ)
Sulfalene (SMPZ)
MFCD00437754
Sulfalene (Standard)
N-(3-Methoxypyrazin-2-yl)sulfanilamide
Sulfanilamide, N1-(3-methoxypyrazinyl)-(8CI)
Oprea1_010520
SCHEMBL28404
4-Amino-N-(3-methoxypyrazinyl)-benzenesulfonamide
MLS001304101
MLS001304170
Butadiene sulfone;3-Sulfolene
4-Amino-N-(3-methoxypyrazin-2-yl);benzenesulfonamide
CHEMBL1525826
GTPL10174
HY-A0130R
HMS2866D06
HMS3604L11
AAA15247
BCP30869
HY-A0130
SMSF0004129
Tox21_111844
WLN: T6N DNJ BO1 CMSWR DZ
AC-750
BBL023067
s4976
STK386859
AKOS000538590
Tox21_111844_1
CB03172
CCG-112228
CS-8165
DB00664
KS-5333
NCGC00160482-02
Sulfalene 100 microg/mL in Acetonitrile
BIM-0013167.P001
DB-043149
NS00003478
A11687
D01216
EN300-124886
SBI-0013167.0001
Sulfalene;Sulfamethoxypyrazine;Sulfametopyrazine
SR-01000817374
Q6577302
SR-01000817374-3
BRD-K17205817-001-06-1
Z277559098
Sulfametopyrazine; AS-18908; Sulfalene; Sulfaleno;Sulfamethoxypyrazine
205-804-7
5175-55-3
Solubility of 4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide, a compound known for its diverse applications, exhibits moderate solubility in aqueous environments. Its solubility characteristics are influenced by several factors:
It is worth noting that while this compound dissolves in water, its specific solubility can differ based on the solvent system and concentration conditions employed. In summary, the solubility of 4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide represents a balance of its molecular structure and environmental factors, making it a fascinating subject in the study of chemical behavior.