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Aminopyridine

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Identification
Molecular formula
C13H15Cl2N3O
CAS number
69759-11-1
IUPAC name
4-amino-N-(3-methyl-2-pyridyl)benzamide;dihydrochloride
State
State

At room temperature, it is found in a solid state, typically as a crystalline powder.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.00
Boiling point (Celsius)
402.66
Boiling point (Kelvin)
675.81
General information
Molecular weight
291.19g/mol
Molar mass
291.1900g/mol
Density
1.2938g/cm3
Appearence

The compound typically appears as an off-white to pale yellow crystalline powder. It is known for its moisture-sensitive nature and should be stored in airtight containers to prevent degradation.

Comment on solubility

Solubility of 4-amino-N-(3-methyl-2-pyridyl)benzamide; dihydrochloride

The solubility characteristics of 4-amino-N-(3-methyl-2-pyridyl)benzamide; dihydrochloride can be summarized as follows:

  • Solvent Compatibility: This compound is typically more soluble in polar solvents, such as water, due to the presence of the dihydrochloride moiety, which can easily ionize.
  • Temperature Dependence: Solubility may increase with temperature, which is a common behavior for many organic compounds.
  • pH Influence: The solubility may be affected by the pH of the solution, with acidic conditions aiding its dissolution due to the ionization of the amine group.

Furthermore, it is noteworthy that the solubility profile of this compound is essential for its biological and chemical applications. As an academic reference, "the solubility of a compound can significantly influence its bioavailability and therapeutic efficacy." Thus, understanding its solubility behavior is crucial for effective formulation and application strategies.

In summary, the solubility of 4-amino-N-(3-methyl-2-pyridyl)benzamide; dihydrochloride is characterized by:

  1. High solubility in polar solvents
  2. Dependence on temperature and pH
  3. Potential variation based on ionic interactions

These attributes make it a versatile compound in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 4-amino-N-(3-methyl-2-pyridyl)benzamide Dihydrochloride

4-amino-N-(3-methyl-2-pyridyl)benzamide, also known as a dihydrochloride salt, is a fascinating compound within the realm of medicinal chemistry. This compound features a pyridine ring, which is known for its engaging properties in numerous biological applications. Here are some noteworthy points:

  • Pyridine-based Pharmacology: The presence of the pyridine ring in this compound contributes to its potential as a pharmacological agent, acting as a scaffold for various therapeutic strategies.
  • Antimicrobial Properties: Compounds derived from pyridine are often investigated for their antimicrobial activities, which has led to several advances in drug development.
  • Amino Group Importance: The amino group (-NH2) tends to enhance solubility and reactivity, making this compound suitable for further modifications and applications in organic synthesis.
  • Structure-Activity Relationship (SAR): The unique arrangement of functional groups can be studied to enhance compound efficacy and selectively target specific biological pathways.

Furthermore, this compound interacts intriguingly with other biological molecules, providing insights into receptor-ligand binding and enzyme inhibition. The exploration of 4-amino-N-(3-methyl-2-pyridyl)benzamide dihydrochloride continues to reveal potential therapeutic avenues and fuels ongoing research in the quest for new medications.

As scientists delve deeper into its properties, they often quote, “Chemistry is the art of transformation,” proving especially true with compounds like this that are pivotal in both research and practical applications.

Synonyms
2-(P-AMINOBENZAMIDO)-3-PICOLINE DIHYDROCHLORIDE
17710-07-5
Benzamide, p-amino-N-(3-methyl-2-pyridyl)-, dihydrochloride
3-Picoline, 2-(p-aminobenzamido)-, dihydrochloride
Pyridine, 2-(p-aminobenzamido)-3-methyl-, dihydrochloride
DTXSID20170254
DTXCID5092745
4-amino-N-(3-methylpyridin-2-yl)benzamide;dihydrochloride
4-amino-N-(3-methylpyridin-2-yl)benzamide dihydrochloride
MT3Z4X6974
Benzamide, 4-amino-N-(3-methyl-2-pyridinyl)-, dihydrochloride
Benzamide, 4-amino-N-(3-methyl-2-pyridinyl)-, hydrochloride (1:2)