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Sulfameter

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Identification
Molecular formula
C11H13N3O3S
CAS number
651-06-9
IUPAC name
4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide
State
State

At room temperature, sulfameter is typically in a solid state. It remains stable under normal conditions and should be handled with care to avoid any contact with acids or bases which may cause degradation.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
203.00
Boiling point (Kelvin)
476.15
General information
Molecular weight
280.33g/mol
Molar mass
280.3270g/mol
Density
1.4700g/cm3
Appearence

Sulfameter appears as a crystalline powder that is often off-white to slightly yellow in color. Being a powder, it can form clumps but is more commonly found as a free-flowing substance. It may have a slight odor reminiscent of sulfonamides.

Comment on solubility

Solubility of 4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide

The solubility of the compound 4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide can be described through several key points:

  • Polarity: The presence of both amino (-NH2) and sulfonamide (-SO2NH2) functional groups increases the compound's polar characteristics, promoting its solubility in polar solvents.
  • Solvent interactions: This compound is expected to exhibit good solubility in water due to hydrogen bonding capabilities with the solvent molecules.
  • Temperature effect: Typically, an increase in temperature can enhance the solubility of most compounds, including this one, by allowing more interactions through kinetic energy.
  • pH influence: The solubility can vary with pH; in more acidic or basic environments, the ionization of the amino and sulfonamide groups may further enhance solubility.

To summarize, the solubility of 4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide is significant in polar solvents, driven by its functional groups and external conditions such as temperature and pH. As with many sulfonamides, it presents a fascinating study in the interplay between molecular structure and solubility behavior.

Interesting facts

Interesting Facts about 4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide

4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide is a fascinating compound that stands out in the field of medicinal chemistry. This compound is known for its potential therapeutic applications, particularly due to its structural features that allow it to interact with biological systems.

Key Highlights

  • Pharmaceutical Relevance: The compound is part of a broader class of sulfonamides, which have been extensively studied for their antibacterial properties.
  • Structural Diversity: The inclusion of a dimethyloxazol moiety adds unique pharmacophoric characteristics that can enhance biological activity and specificity.
  • Potential Applications: Due to its amine and sulfonamide functional groups, this compound might engage in various biological interactions, making it a candidate for drug development.
  • Research Interest: The study of such compounds often leads to insights into novel mechanisms of action, potentially paving the way for new therapeutic agents.

Researchers are particularly intrigued by the ability of 4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide to undergo various chemical modifications, which can fine-tune its pharmacological profile. As noted by chemists, engaging with this compound can lead to:

  1. Innovation in structural biology.
  2. Enhanced understanding of drug interactions at the molecular level.
  3. Exploration of resistance mechanisms against pathogens for better drug design.

In conclusion, 4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide represents an exciting intersection of chemistry and biology. This compound exemplifies how small changes in molecular structure can lead to significant impacts in biological activity, providing a fertile ground for future research and development in medicinal chemistry.

Synonyms
SULFAMOXOLE
729-99-7
Sulfamoxol
Sulphamoxole
Sulfamoxolum
Sulfadimethyloxazole
Oxasulfa
Sulfmidil
Tardamid
4-Amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamide
Justamil
Sulfavigor
Tardamide
Sulfuno
Solfamossolo
4,5-Dimethyl-2-sulfanilamidooxazole
N1-(4,5-Dimethyl-2-oxazolyl)sulfanilamide
Solfamossolo [DCIT]
2-(p-Aminobenzenesulfonamido)-4,5-dimethyloxazole
NSC 683535
p-Aminobenzenesulfonyl-2-amino-4,5-dimethyloxazole
Sulfamoxol [INN-Spanish]
Sulfamoxolum [INN-Latin]
N(sup 1)-(4,5-Dimethyl-2-oxazolyl)sulfanilamide
4-Amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide
CHEBI:55548
2-(p-Aminobenzolsulfonamido)-4,5-dimethyloxazol
4-amino-N-(dimethyl-1,3-oxazol-2-yl)benzene-1-sulfonamide
EINECS 211-982-7
Benzenesulfonamide, 4-amino-N-(4,5-dimethyl-2-oxazolyl)-
NSC-683535
Sulfamoxole [USAN:INN:BAN]
HGG82XE020
Oxazole, 2-(p-aminophenylsulfonylamino)-4,5-dimethyl-
SULFAMOXOLE [MI]
SULFAMOXOLE [INN]
SULFAMOXOLE [USAN]
SULFAMOXOLE [MART.]
SULFAMOXOLE [WHO-DD]
2-(p-Aminobenzolsulfonamido)-4,5-dimethyloxazol [German]
DTXSID5023617
Sulfanilamide, N(sup 1)-(4,5-dimethyl-2-oxazolyl)-
Sulfamoxol (INN-Spanish)
Sulfamoxolum (INN-Latin)
SULFAMOXOLE (MART.)
sulfamoxolo
DTXCID603617
J01EC03
211-982-7
4-amino-N-(4,5-dimethyloxazol-2-yl)benzenesulfonamide
NSC683535
MFCD00005303
Sulfono
Sulfamoxol 100 microg/mL in Acetonitrile
N1-(4,5-Dimethyloxazol-2-yl)sulfanilamide
N1-(4,5-Dimethyloxazol-2-yl)-sulfanilamide
UNII-HGG82XE020
Sulfano
Sulfune
Sulfamoxole (USAN/INN)
Epitope ID:122242
Sulfanilamide, N1-(4,5-dimethyl-2-oxazolyl)-
SCHEMBL151518
CHEMBL2105399
GTPL12744
HY-B1782
AKOS022507464
DB08798
NS-04235
DB-055711
Sulfamoxole 1000 microg/mL in Acetonitrile
CS-0013814
NS00000006
D02516
G12050
N(1)-(4,5-Dimethyl-2-oxazolyl)sulfanilamide
Sulfamoxole, VETRANAL(TM), analytical standard
SR-01000944561
Q6577297
SR-01000944561-1
BRD-K19742012-001-01-5
BRD-K19742012-001-02-3
4-Amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide #
4-amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzene-1-sulfonamide
InChI=1/C11H13N3O3S/c1-7-8(2)17-11(13-7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6H,12H2,1-2H3,(H,13,14