Interesting facts
Interesting Facts About 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide, often referred to in the scientific community for its unique structure and properties, belongs to the class of sulfonamide compounds. Here are some noteworthy aspects:
- Pharmaceutical Significance: Sulfonamides, including this compound, have been pivotal in medicinal chemistry, serving as the groundwork for the development of several antibacterial agents. Their efficacy against a range of bacterial infections highlights their importance in the pharmaceutical industry.
- Structural Features: The incorporation of a thiadiazole ring is particularly intriguing, as it greatly influences the biological activity of the compound. Thiadiazoles are known for their versatility in medicinal chemistry, often leading to compounds with anti-inflammatory and analgesic properties.
- Mechanism of Action: Compounds like this one can function by inhibiting bacterial enzymes. Though classification may vary, the mechanism generally involves competing for active sites, thus disrupting essential metabolic pathways in bacteria.
- Research Potential: The unique combination of the amino group with the sulfonamide and heterocyclic thiadiazole positions this compound as a candidate for further research. Studies have indicated that modifications at various positions can enhance both potency and spectrum of activity, making it a fascinating subject for synthetic chemists.
- Environmental Interest: Some sulfonamide derivatives have been monitored in environmental studies, shedding light on their persistence and potential effects on ecosystems. Understanding such impacts is crucial for developing safer pharmaceuticals.
As a chemistry student or researcher, diving into the nuances of 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide opens a window to explore diverse avenues of study—from medicinal applications to environmental assessments. The blend of **biological activity** with the **complexity of its molecular structure** makes it a compound worthy of further exploration!
Synonyms
Sulfaethidole
94-19-9
Sulphaethidole
Sul-Spansion
Sulfaethylthiadiazole
Sulfaethidiole
Globucid
Sulfaethidol
Etazole
4-Amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
Aethazolum
Aethazol
Berlophen
Globuzid
Sethadil
Etazol
Sulfa-perlongit
Sul-Spantab
Sulfaetidol
Tardipyrine
SETD
4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
Globuzid [German]
Ethazole (pharmaceutical)
Solfetidolo
Sulfaethidolum
Solfetidolo [DCIT]
Sulfaethidole [INN]
Sulfaetidol [INN-Spanish]
VK 55
Sulfaethidolum [INN-Latin]
2-Sulfanilamidoaethylthiodiazol
Globucin
4-amino-n-(5-ethyl-1,3,4-thiadiazol-2-yl)benzene-1-sulfonamide
UNII-R77Q4O5ZMD
4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzene sulfonamide
EINECS 202-312-4
R77Q4O5ZMD
Sulfaethidole [INN:BAN:NF]
BRN 0261474
2-Sulfanilamidoaethylthiodiazol [German]
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)sulfanilamide
p-Aminobenzolsulfonamido-ethyl-thiodiazol
Sul-Spansion (TN)
Sulfaethidole (INN)
DTXSID4046286
SULFAETHIDOLE [MI]
Benzenesulfonamide, 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-
Sulfanilamide, N-(5-ethyl-1,3,4-thiadiazol-2-yl)-
SULFAETHIDOLE [WHO-DD]
DTXCID2026286
4-27-00-08075 (Beilstein Handbook Reference)
N1-(5-Ethyl-1,3,4-thiadiazol-2-yl)sulfanilamide
NCGC00160667-01
2-Sulfanilamido-5-ethyl-1,3,4-thiadiazol
2-Sulfanilamido-5-ethyl-1,3,4-thiadiazole
Sulfaetidol (INN-Spanish)
Sulfaethidolum (INN-Latin)
CAS-94-19-9
N(sup 1)-(5-Ethyl-1,3,4-thiadiazol-2-yl)sulfanilamide
TimTec1_000569
Oprea1_047146
Oprea1_050882
MLS001204918
SCHEMBL152872
CHEMBL1355299
CHEBI:107668
BDBM223479
HMS1535J19
HMS2231B23
HMS3370F08
[(4-aminophenyl)sulfonyl](5-ethyl(1,3,4-thiadiazol-2-yl))amine
AAA09419
Tox21_111971
BBL025945
STK099239
AKOS000300986
Tox21_111971_1
CCG-103308
NCGC00160667-03
SMR000516737
VS-08163
NS00007877
D02449
EN300-191266
G28650
AB00876247-06
SR-01000314048
US9320734, 109
SR-01000314048-1
BRD-K56881825-001-01-2
Q27185990
Z56791660
F0266-1318
4-Amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide #
4-AMINO-N~1~-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)-1-BENZENESULFONAMIDE
202-312-4
Solubility of 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
The solubility of 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide can be an intriguing topic due to its unique chemical structure. This compound, with the molecular formula C10H12N4O2S, is known for certain distinct solubility characteristics:
It is also essential to consider that solubility can be influenced by factors such as pH and ionic strength of the solution, which can either promote or hinder the dissolution process. In conclusion, the solubility of this compound showcases its properties and relative behavior in various environments, making it a compelling subject of study for chemists.