Interesting facts
4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide: A Compound of Interest
The compound 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide, commonly known in the scientific community for its versatile applications, holds a fascinating position in the realm of medicinal chemistry. Here are some intriguing facts:
- Medicinal Properties: This compound is notable for its use in the development of pharmaceutical agents, particularly regarding antibiotic properties. Its unique structure contributes to therapeutic efficacy against various bacterial infections.
- Pyrimidine Derivative: The presence of a pyrimidine moiety enhances its biological activity. Pyrimidines are essential building blocks in biochemistry, being part of nucleic acids like DNA and RNA.
- Sulfonamide Component: The sulfonamide group in the structure provides the compound with reactive properties that can be leveraged in drug design. Sulfonamides have been historically important as they were among the first antibiotics developed.
- Research Applications: Beyond its medicinal uses, research indicates that derivatives and analogs of this compound could lead to advancements in cancer treatment, making it a subject of ongoing investigation.
- Structure-Activity Relationship (SAR): The modification of functional groups around the core structure highlights the importance of SAR studies in medicinal chemistry, illustrating how slight changes can significantly affect biological outcomes.
In the words of one noted chemist, "Understanding the interplay between structure and function is the cornerstone of developing new therapeutic agents." This quote encapsulates the journey of researchers exploring compounds like 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide in the quest for innovative solutions to medical challenges.
As a compound rich in biochemical significance, it represents not only a focal point in current research but also a potential pathway toward future healthcare advancements.
Synonyms
sulfameter
651-06-9
Sulfamethoxydiazine
5-Methoxysulfadiazine
Sulfametoxydiazine
Sulphamethoxydiazine
Sulfamethoxine
Sulfametin
Sulla
Sulfamethoxypyrimidine
Ultrax
4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide
Sulfametorine
Sulphameter
Methoxypyrimal
Sulfamethoxydin
Berlicid
Sulfa-5-methoxypyrimidine
Sulfamethorine
Bayrena
Dairena
Durenat
Juvoxin
Kinecid
Kirocid
Longasulf
Kiron
Sulfametoxidiazina
Solfametossidiazina
Sulfametinum
AHR-857
Sulfametoxipirimidine
Supramid
Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyrimidinyl)-
Sulfametoxydiazinum
Bayer 5400
2-Sulfanilamido-5-methoxypyrimidine
5-Methoxy-2-sulfanilamidopyrimidine
Sulfameter [USAN]
4-Amino-N-(5-methoxy-2-pyrimidinyl)benzenesulfonamide
sulfamethoxidiazine
2-Sulfanilamido-5-methoxypyrimidin
Sulfameter (Bayrena)
2-(4-Aminobenzenesulfonamido)-5-methoxypyrimidine
SH 613
NSC 683528
N(sup 1)-(5-Methoxy-2-pyrimidinyl)sulfanilamide
EINECS 211-480-8
MFCD00006067
I-2586
NSC-683528
NSC-757874
BRN 0621130
DTXSID5023613
Sulfametoxydiazinum [INN-Latin]
UNII-3L179F09D6
CHEBI:53727
Sulfametoxidiazina [INN-Spanish]
4-amino-N-(5-methoxypyrimidin-2-yl)benzene-1-sulfonamide
BAY-5400
Sulfametoxydiazine [INN]
SH-613
3L179F09D6
Sulfanilamide, N(sup 1)-(5-methoxy-2-pyrimidinyl)-
DTXCID003613
Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyridimidinyl)-
N(1)-(5-Methoxy-2-pyrimidinyl)sulfanilamide
5-25-12-00525 (Beilstein Handbook Reference)
Sulfameter (USAN)
NSC683528
Sulfametoxydiazine;5-Methoxysulfadiazine
NCGC00016530-01
CAS-651-06-9
Sulfametoxydiazine (INN)
Sulfametoxydiazinum (INN-Latin)
Sulfametoxidiazina (INN-Spanish)
Sulfametoxidine
Sulfametorinum
Sulfamethoxydine
Solfametossidiazina [DCIT]
SR-01000721917
N1-(5-Methoxy-2-pyrimidinyl)sulfanilamide
2-Sulfanilamido-5-methoxypyrimidin [German]
Sulfamethoxydiazin
sulfamethoxydiazinum
Prestwick_1048
Sulla (TN)
Sulfameter (Standard)
Spectrum_001149
SULFAMETER [MI]
Prestwick0_000769
Prestwick1_000769
Prestwick2_000769
Prestwick3_000769
Spectrum2_001428
Spectrum3_001463
Spectrum4_000426
Spectrum5_000981
2-Sulfa-5-methoxypyrimidine
Oprea1_482593
SCHEMBL79417
BSPBio_000818
BSPBio_002985
KBioGR_000752
KBioSS_001629
MLS000069640
BIDD:GT0693
DivK1c_000468
SPECTRUM1501155
SPBio_001536
SPBio_002757
BPBio1_000900
CHEMBL1200359
SULFAMETER [ORANGE BOOK]
GPTONYMQFTZPKC-UHFFFAOYSA-
GTPL12641
HMS501H10
HY-B0213R
KBio1_000468
KBio2_001629
KBio2_004197
KBio2_006765
KBio3_002485
J01ED04
NINDS_000468
HMS1570I20
HMS1921L15
HMS2092J03
HMS2097I20
HMS2233B12
HMS3374J11
HMS3655A11
HMS3714I20
Pharmakon1600-01501155
SULFAMETOXYDIAZINE [WHO-DD]
HY-B0213
PXB48396
Tox21_110478
CCG-38965
NSC757874
s1618
AKOS015897255
Tox21_110478_1
DB06821
FS27932
IDI1_000468
NCGC00016530-02
NCGC00016530-03
NCGC00016530-04
NCGC00016530-06
NCGC00016530-07
NCGC00094915-01
NCGC00094915-02
AC-19932
AC-32614
AS-13912
SMR000058215
SY101966
N1-(5-Methoxypyrimidin-2-yl)sulfanilamide
SBI-0051665.P002
DB-054761
AB00052227
NS00010604
SW197118-3
D02517
EN300-118317
Sulfameter, VETRANAL(TM), analytical standard
AB00052227-11
AB00052227_12
AB00052227_13
SR-01000721917-2
SR-01000721917-3
BRD-K87492696-001-05-8
BRD-K87492696-001-09-0
BRD-K87492696-001-15-7
BRD-K87492696-001-16-5
Q15410181
Z1511483974
4-amino-N-[5-(methyloxy)pyrimidin-2-yl]benzenesulfonamide
211-480-8
4-Amino-N-(5-methoxy-2-pyrimidinyl)benzenesulfonamide;5-Methoxysulfadazine;Sulfamethoxydiazine
InChI=1/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
Solubility of 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide
The solubility of 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide (C11H12N4O3S) can exhibit several interesting characteristics, particularly due to its complex molecular structure. As a sulfonamide compound, its solubility is influenced by a variety of factors, including:
However, it is key to note that while some sulfonamides are known to be soluble in water, the specific solubility of this compound may vary due to its unique structural features. Solubility can often be represented in terms of concentration, such as 'How much of the compound dissolves in a certain volume of solvent.' Therefore, experimental solubility data would be critical for understanding its behavior in practical applications.
Overall, you can anticipate a moderate solubility in suitable solvents, but thorough solubility testing would be essential to provide an accurate profile for practical usage.