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Sulfaphenazole

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Identification
Molecular formula
C15H14N4O2S
CAS number
526-08-9
IUPAC name
4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide
State
State

Sulfaphenazole is typically in a solid state at room temperature.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
559.30
Boiling point (Kelvin)
832.45
General information
Molecular weight
314.37g/mol
Molar mass
314.3660g/mol
Density
1.4000g/cm3
Appearence

Sulfaphenazole appears as a white or slightly off-white crystalline powder.

Comment on solubility

Solubility of 4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide

The solubility of 4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide can be quite complex due to its structural characteristics. Generally, the key factors influencing the solubility of this compound include:

  • Polarity: The presence of sulfonamide (-SO₂NH₂) and amino (-NH₂) groups tends to increase its polarity, enhancing solubility in polar solvents like water.
  • Hydrogen Bonding: This compound may engage in strong hydrogen bonding interactions with solvents, which can significantly affect solubility.
  • Temperature: As with many organic compounds, solubility may increase with temperature, allowing for better dissolution in common solvents.
  • pH Level: The solubility can also be influenced by the pH of the solution, as ionization of the amino group may occur.

It is worth noting that, in general terms, compounds like 4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide may exhibit variable solubility profiles depending on the solvent environment, often displaying better solubility in acidic conditions due to their ability to become protonated.

In summary, the solubility of 4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide can be described as:

  1. Polar solvents: Better solubility
  2. Temperature: Higher temperatures may improve solubility
  3. pH: Critical for determining the ionic state

Understanding these factors is essential for effectively utilizing this compound in various applications.

Interesting facts

Interesting Facts about 4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide

4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide, often referred to in scientific literature, is a compound that stands out due to its unique structural characteristics and potential applications in various fields. Here are some intriguing aspects about this compound:

  • Pharmaceutical Relevance: This compound belongs to the sulfonamide class of drugs, which have made a significant impact on modern medicine, particularly as antibacterial agents. The structure can influence its biological activity, making it a focal point of research.
  • Pyrazole Derivatives: The inclusion of the pyrazole ring not only adds complexity to the molecule but also enhances its ability to interact with biological targets. Pyrazole derivatives are known for anti-inflammatory and antipyretic properties, broadening the potential therapeutic applications.
  • Structure-Activity Relationship: Understanding how modifications to the phenyl and pyrazole groups affect the compound's activity provides valuable insights into drug design. Such studies can lead to the development of more effective agents with fewer side effects.
  • Research Opportunities: The unique features of this compound offer various avenues for research. For instance, exploring its mechanism of action can contribute to the development of new therapeutic strategies against resistant bacterial strains.

In conclusion, 4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide is not just a chemical compound; it embodies a rich tapestry of scientific exploration, innovation, and potential health benefits. As highlighted by prominent chemists, "the potential of synthetic compounds lies in their ability to address pressing challenges in healthcare." This perspective makes further study of this compound not only fascinating but essential.

Synonyms
Sulfapyrazole
SULFAZAMET
852-19-7
Sulfapirazol
Sulfapyrazol
Sulfazamet [USAN]
Solfapirazolo
Sulfapyrazolum
Sulphapyrazole
Solfapirazolo [DCIT]
Vesulong vet.
Sulfapyrazole [INN]
Sulfapirazol [INN-Spanish]
Sulfapyrazolum [INN-Latin]
K980HZ9QO4
SULFAZAMET [MI]
EINECS 212-707-3
Ba 18605
DTXSID30234391
Benzenesulfonamide, 4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-
Sulfapirazol (INN-Spanish)
Sulfapyrazolum (INN-Latin)
DTXCID30156882
212-707-3
sulfamethylphenazole
4-amino-N-(5-methyl-2-phenylpyrazol-3-yl)benzenesulfonamide
1420043-51-1
Sulfamethylphenazole; Sulfapyrazole; Vesulong
4-Amino-N-(5-methyl-2-phenyl-2H-pyrazol-3-yl)-benzene-13C6-sulfon-amide
UNII-K980HZ9QO4
Sulfazamet (USAN/INN)
SCHEMBL193436
CHEMBL2104908
MTERSQYMYBGZTP-UHFFFAOYSA-N
1-Phenyl-3-methyl-5-sulfanilamidopyrazole
NS00009771
D05954
EN300-18563421
Sulfamethylphenazole 100 microg/mL in Acetonitrile
Q27282121
4-Amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide