Interesting facts
Interesting Facts about 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
This compound is a fascinating member of the sulfonamide family, which has been a field of extensive research in medicinal chemistry. Here are some engaging facts about this compound:
- Pharmacological Potential: As a sulfonamide, it has garnered interest for its potential use in pharmaceuticals, particularly as an anti-bacterial agent. Its structural features can influence its activity and specificity against various pathogens.
- Structure-Activity Relationship (SAR): The presence of the 5,6-dimethoxypyrimidine moiety could enhance its bioavailability and efficacy. Understanding how modifications to the core structure affect its chemical behavior is a cornerstone of drug development.
- Heterocyclic Chemistry: This compound features a pyrimidine ring, which is pivotal in many biological systems. Pyrimidines are essential bases in nucleic acids, making the study of this compound beneficial in understanding genetic processes.
- Versatile Synthetic Pathways: The synthesis of such compounds often utilizes various organic reactions, providing practitioners with a rich landscape of synthetic methodologies to explore and master.
In summary, 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide is not merely a chemical entity but a compound with immense potential and implications in medicinal chemistry. As researchers dive deeper into its properties, its applications could unfold even further, adding to the rich tapestry of organic compounds.
Synonyms
SULFADOXINE
2447-57-6
Sulphadoxine
Sulfadoxin
Fanasil
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
Solfadossina
Ro 4-4393
Solfadossina [DCIT]
Sulfadoxinum [INN-Latin]
Fanasulf
Sulfadoxina [INN-Spanish]
WR 4873
EINECS 219-504-9
NSC-759319
Ro-4-4393
BRN 0625453
CHEBI:9329
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide
DTXSID6023608
Fansidar (Salt/Mix)
SULFADOXINE [MI]
Sulformethoxine
Sulformetoxine
Ro-44393
SULFADOXINE [INN]
SULFADOXINE [JAN]
SULFADOXINE [USAN]
88463U4SM5
SULFADOXINE [VANDF]
WR-4073
SULFADOXINE [MART.]
Sulfadoxine [USAN:USP:INN:BAN:JAN]
J21.373J
SULFADOXINE [USP-RS]
SULFADOXINE [WHO-DD]
SULFADOXINE [WHO-IP]
DTXCID703608
Sulphormetoxin
SULFADOXINE [ORANGE BOOK]
SULFADOXINE [EP MONOGRAPH]
SULFADOXINE [USP MONOGRAPH]
5-25-13-00306 (Beilstein Handbook Reference)
FANSIDAR COMPONENT SULFADOXINE
NSC 759319
Sulphorthodimethoxine
N1-5,6-Dimethoxy-4-pyrimidinylsulfanilamide
Sulfadoxinum (INN-Latin)
Sulfadoxina (INN-Spanish)
SULFADOXINE (MART.)
SULFADOXINE (USP-RS)
SULFADOXINE (EP MONOGRAPH)
SULFADOXINE (USP MONOGRAPH)
Sulfadoxine (USAN:USP:INN:BAN:JAN)
Sulforthamidine
SULFADOXINE COMPONENT OF FANSIDAR
219-504-9
pjsfriwcgohtnf-uhfffaoysa-n
Sulforthomidine
Sulphormethoxine
Sulfadoxina
Sulfadoxinum
Fanzil
Benzenesulfonamide, 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)-
4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
4-Sulfanilamido-5,6-dimethoxypyrimidine
Sulfadoxine (Sulphadoxine)
MFCD00792890
N'-(5,6-Dimethoxy-4-pyrimidyl)sulfanilamide
6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
NCGC00016612-01
Orthosulfin
CAS-2447-57-6
4-amino-N-[5,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide
SR-05000001523
N1-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
Sulfadoxine (JAN/USP/INN)
UNII-88463U4SM5
Sanasil: Sulfadoxine: Sulformetoxin
N(sup 1)-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
1173021-35-6
WR 4073
Sulfadoxine (Standard)
Prestwick0_001094
Prestwick1_001094
Prestwick2_001094
Prestwick3_001094
CHEMBL1539
SCHEMBL41069
BSPBio_001168
MLS002154150
SPBio_003054
BPBio1_001286
Sulfadoxin, >=95% (TLC)
GTPL10173
HY-B0439R
MSK4006
HMS1571K10
HMS2090P07
HMS2094C19
HMS2098K10
HMS2230E05
HMS3371I15
HMS3715K10
Pharmakon1600-01506086
HY-B0439
SULFADOXINUM [WHO-IP LATIN]
Tox21_110523
BBL023187
NSC759319
s2511
STL356042
AKOS015897281
Tox21_110523_1
AC-8428
AS01376
CCG-213610
DB01299
KS-5334
NCGC00016612-02
NCGC00016612-04
NCGC00016612-05
SMR000857259
SY045794
SBI-0206941.P001
DB-046463
Sulfadoxin 1000 microg/mL in Acetonitrile
AB00514044
NS00008538
C07630
D00580
EN300-118712
H10765
Sulfadoxin, VETRANAL(TM), analytical standard
AB00514044-06
AB00514044_07
AB00514044_08
A817328
Q411557
SR-05000001523-1
SR-05000001523-3
BRD-K55250441-001-03-1
BRD-K55250441-001-06-4
BRD-K55250441-001-12-2
BRD-K55250441-001-13-0
Sulfadoxin, certified reference material, TraceCERT(R)
Z1515385080
4-azanyl-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
Sulfadoxine, European Pharmacopoeia (EP) Reference Standard
Sulfadoxine, United States Pharmacopeia (USP) Reference Standard
Solubility of 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
The solubility of 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide can be influenced by various factors that dictate the compound's behavior in different solvents. Here are some key considerations:
In conclusion, the solubility of 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide is expected to be relatively moderate to high in polar solvents, especially in neutral to slightly acidic conditions, where its functional groups remain protonated and can interact favorably with the solvent.