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Silver sulfadiazine

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Identification
Molecular formula
C10H9AgN4O2S
CAS number
22199-08-2
IUPAC name
4-amino-N-pyrimidin-2-yl-benzenesulfonamide;silver
State
State

At room temperature, silver sulfadiazine is a solid. It is commonly formulated into a cream for topical applications.

Melting point (Celsius)
285.00
Melting point (Kelvin)
558.15
Boiling point (Celsius)
1 609.00
Boiling point (Kelvin)
1 882.15
General information
Molecular weight
357.13g/mol
Molar mass
357.1330g/mol
Density
2.2800g/cm3
Appearence

Silver sulfadiazine appears as a white or slightly yellow crystalline powder. It is commonly used in a topical cream form for its antibacterial properties, particularly in the treatment of burn wounds.

Comment on solubility

Solubility of 4-amino-N-pyrimidin-2-yl-benzenesulfonamide Silver Salt

The solubility of 4-amino-N-pyrimidin-2-yl-benzenesulfonamide silver salt varies depending on environmental factors and the medium in which it is introduced. Generally, the solubility can be influenced by several key factors:

  • pH Level: The solubility of the compound can increase or decrease based on the acidity or basicity of the solution.
  • Temperature: Higher temperatures often enhance solubility, causing the compound to dissolve more readily.
  • Presence of Other Ions: The presence of competing ions or solubilizing agents can alter solubility characteristics.
  • Solvent Type: Polar solvents may facilitate better solubility compared to non-polar solvents.

In general, silver salts tend to exhibit reduced solubility in aqueous solutions, which may make 4-amino-N-pyrimidin-2-yl-benzenesulfonamide silver salt less soluble in water. Additionally, the complexation with Ag+ ions can lead to unique solubility behaviors that may be advantageous in specific applications, such as in medicinal chemistry where solubility can affect bioavailability.

As a rule of thumb, understanding solubility is critical in predicting how this compound can interact in various chemical environments and systems. Thus, careful considerations in experimental designs are vital for its effective usage in scientific applications.

Interesting facts

Interesting Facts about 4-amino-N-pyrimidin-2-yl-benzenesulfonamide; silver

4-amino-N-pyrimidin-2-yl-benzenesulfonamide; silver is a notable compound in the realm of medicinal chemistry, particularly due to its potential applications in antimicrobial therapy. Below are some engaging insights about this unique compound:

  • Dual Activity: This compound combines the properties of a sulfonamide with a pyrimidine ring, potentially enhancing its effectiveness in targeting bacteria while reducing resistance.
  • Silver Ion Influence: The incorporation of silver ions is critical, as silver has long been recognized for its antimicrobial properties, further augmenting the compound's ability to combat pathogens.
  • Inhibition of Bacterial Growth: The structure allows for effective inhibition mechanisms against various bacterial strains, making it a promising candidate for developing new antibiotics.
  • Chemotherapy Synergy: There is ongoing research into combining this compound with other chemotherapeutic agents, enhancing overall efficacy while minimizing side effects.
  • Research Potential: Its unique chemical structure presents opportunities for further scientific exploration, including modifications that could lead to more potent derivatives.

As one scholar aptly put it, "The future of medicine is in the fusion of conventional chemistry with innovative compounds that enhance therapeutic efficiency." In the case of 4-amino-N-pyrimidin-2-yl-benzenesulfonamide; silver, this fusion is not only relevant but essential in the fight against resistant infectious agents.

As research continues to unfold, this compound stands as a testament to the creative potential within chemical sciences, highlighting the importance of interdisciplinary approaches in solving pressing health challenges.

Synonyms
4-amino-N-pyrimidin-2-ylbenzenesulfonamide;silver
1152234-18-8
NCGC00188438-01
BENZENESULFONAMIDE, 4-AMINO-N-2-PYRIMIDINYL-, SILVER(1+) SALT (1:1)
RefChem:1078660
SCHEMBL34517
s4822