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4-Aminothiophenol

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Identification
Molecular formula
C6H7NS
CAS number
1193-02-0
IUPAC name
4-aminobenzenethiol
State
State

At room temperature, 4-aminothiophenol is generally found in a solid state. It is not very soluble in water but may dissolve in various organic solvents.

Melting point (Celsius)
30.00
Melting point (Kelvin)
303.15
Boiling point (Celsius)
209.00
Boiling point (Kelvin)
482.15
General information
Molecular weight
125.19g/mol
Molar mass
125.1890g/mol
Density
1.2160g/cm3
Appearence

4-Aminothiophenol is typically found as an off-white to light brown solid. It may have a slight odor characteristic of organic compounds with thiol groups, which is often described as a mild, unpleasant "sulfide-like" smell.

Comment on solubility

Solubility of 4-aminobenzenethiol

4-aminobenzenethiol, also known as p-aminothiophenol, presents interesting solubility characteristics due to its functional groups. The solubility of this compound can be summarized with the following key points:

  • Solvent Compatibility: 4-aminobenzenethiol is known to be soluble in organic solvents such as ethanol, methanol, and dichloromethane.
  • Water Solubility: The presence of the amine group (-NH2) provides some degree of polarity, but the overall structure limits its solubility in water, making it insoluble or only sparingly soluble.
  • pH Influence: The solubility may increase in acidic conditions due to protonation of the amine group, enhancing its capacity to interact with water molecules.
  • Temperature Effect: As with many organic compounds, solubility typically increases with temperature, making it beneficial to consider this factor when working with 4-aminobenzenethiol.

In summary, while 4-aminobenzenethiol exhibits limited solubility in water, its ability to dissolve in various organic solvents allows for versatility in applications. Understanding these solubility characteristics is crucial for effective utilization in research and industry.

Interesting facts

Interesting Facts About 4-Aminobenzenethiol

4-Aminobenzenethiol, also known as p-aminothiophenol, is an organic compound that serves as an important building block in various fields of chemistry and materials science. Below are some fascinating insights regarding this versatile compound:

  • Functional Group Diversity: The presence of both an amino group (-NH2) and a thiol group (-SH) in its structure makes 4-aminobenzenethiol a versatile molecule for synthesis. This unique combination allows for a range of reactivity in organic reactions, including nucleophilic substitutions and coupling reactions.
  • Applications in Industry: 4-Aminobenzenethiol is widely used in the synthesis of dyes, pharmaceuticals, and agrochemicals. It plays a crucial role in the production of various heterocyclic compounds, which are significant in drug discovery and development.
  • Analytical Chemistry: The thiol group in 4-aminobenzenethiol can easily form complexes with metal ions, making it useful in analytical applications. This property allows it to be applied in analytical chemistry for detecting heavy metals and other trace elements.
  • Biological Relevance: Compounds with thiol groups are known for their antioxidant properties. While 4-aminobenzenethiol itself is primarily a synthetic compound, its derivatives might exhibit biological activities, and research into this area continues to grow.
  • Safety Considerations: As with many thiol-containing compounds, appropriate safety measures must be taken when handling 4-aminobenzenethiol. It is important to work with this compound in a well-ventilated space and to use protective gear, as it can pose health risks if improperly handled.

In summary, 4-aminobenzenethiol's diverse functional capabilities and practical applications make it a significant compound in both synthetic organic chemistry and industrial processes. Its unique properties continue to intrigue scientists and students alike, making it a topic worth exploring further!

Synonyms
4-Aminothiophenol
1193-02-8
4-AMINOBENZENETHIOL
Benzenethiol, 4-amino-
4-Mercaptoaniline
p-Aminothiophenol
p-Aminobenzenethiol
p-Mercaptoaniline
Benzenethiol, p-amino-
p-Aminophenylmercaptan
p-aminophenyl mercaptan
EINECS 214-763-4
BRN 0906904
AI3-52549
8X56V0K20X
P-AMINOPHENYLTHIOL
4-MERCAPTOBENZENAMINE
AMINOBENZENETHIOL, P-
DTXSID1074466
Benzenethiol, 4-amino-(9CI)
DTXCID2033497
6976-04-1 (Na salt)
214-763-4
4-aminobenzene-1-thiol
4-aminothiphenol
4-Amino thiophenol
4-Aminothiophenol, tech grade
4-Amino-benzenethiol
MFCD00007880
4-Aminophenyl mercaptan
UNII-8X56V0K20X
p-amino-thiophenol
4-Aminothiophenol, 97%
SCHEMBL49836
BCP18598
AKOS009156582
AC-1080
CS-W013508
FA02055
PS-3195
4-Aminothiophenol, technical grade, 90%
BP-10049
DB-003458
A0623
NS00023851
EN300-40426
Q27271149
F0001-0317
4-Aminobenzenethiol;4-Aminophenyl mercaptan;4-Mercaptoaniline