Skip to main content

4-Aminobenzohydrazide

ADVERTISEMENT
Identification
Molecular formula
C7H9N3O
CAS number
619-66-9
IUPAC name
4-aminobenzohydrazide
State
State

At room temperature, 4-aminobenzohydrazide is typically found as a solid.

Melting point (Celsius)
219.00
Melting point (Kelvin)
492.15
Boiling point (Celsius)
403.00
Boiling point (Kelvin)
676.15
General information
Molecular weight
151.17g/mol
Molar mass
151.1660g/mol
Density
1.4710g/cm3
Appearence

4-Aminobenzohydrazide is a white to off-white crystalline powder. Its appearance is typically uniform, and it may be presented in the form of fine granules or crystals.

Comment on solubility

Solubility of 4-Aminobenzohydrazide

4-Aminobenzohydrazide, with the chemical formula C7H9N3O, exhibits varying solubility characteristics that are important for its applications in various fields. Understanding the solubility can provide insight into its reactivity, stability, and potential usage in formulations.

In terms of solubility:

  • Water Solubility: 4-Aminobenzohydrazide has limited solubility in water. This can be attributed to its hydrophobic aromatic structure, which tends to reduce intermolecular interaction with polar solvent molecules.
  • Solvents: It is more soluble in polar organic solvents such as:
    • Dimethyl sulfoxide (DMSO)
    • Methanol
    • Ethanol
  • Effects of pH: The solubility may also change with pH, as the presence of protons can enhance solvation through additional hydrogen bonding, particularly in acidic conditions.

As a noteworthy observation, the limited solubility in water could impose restrictions on the compound’s use in aqueous environments, while its better solubility in organic solvents opens doors for diverse applications. As always, it's essential to consider both solubility and stability when working with 4-aminobenzohydrazide in practical applications.

Interesting facts

Interesting Facts About 4-Aminobenzohydrazide

4-Aminobenzohydrazide is an intriguing compound in the realm of organic chemistry, known for its diverse applications and unique properties. Here are some noteworthy facts:

  • Structure and Composition: This compound features a benzene ring substituted with both an amino group and a hydrazine moiety, allowing it to participate in various chemical reactions, making it a valuable intermediate in synthetical processes.
  • Pharmaceutical Applications: 4-Aminobenzohydrazide plays a significant role in pharmaceuticals as it is a crucial building block for the synthesis of various therapeutic agents, particularly in anti-cancer and anti-bacterial research.
  • Reactivity: The presence of both amine and hydrazide functional groups in its structure facilitates a variety of chemical transformations, such as condensation reactions and oxidation reactions, proving its versatility in organic synthesis.
  • Research Interest: Due to its significant biological activity, this compound has gained attention in the scientific community, leading to research focused on its potential as an anti-tumor agent and its effects on different biological systems.
  • Safety Precautions: While working with 4-Aminobenzohydrazide, it is crucial to follow laboratory safety protocols due to its potential hazards. Always wear appropriate personal protective equipment (PPE) to ensure safe handling.

As a compound with a rich chemistry background, 4-Aminobenzohydrazide continues to be a subject of interest, bridging the gap between fundamental research and practical applications in drug development and synthetic chemistry.

Synonyms
4-Aminobenzohydrazide
5351-17-7
4-Aminobenzhydrazide
4-Aminobenzoic acid hydrazide
Aminostimil
Amben hydrazide
p-Aminobenzhydrazide
4-Aminobenzoylhydrazine
p-Aminobenzoic acid hydrazide
p-Aminobenzoyl hydrazide
Benzoic acid, 4-amino-, hydrazide
p-Aminobenzoic hydrazide
p-Aminobenzoylhydrazine
para-Aminobenzhydrazide
NSC 640
BENZOIC ACID, p-AMINO-, HYDRAZIDE
EINECS 226-324-4
BRN 0639053
AI3-52435
p-Amino benzoyl hydrazine
WPBZMCGPFHZRHJ-UHFFFAOYSA-
DTXSID30201720
4-14-00-01159 (Beilstein Handbook Reference)
4-aminobenzoic acid-hydrazide
DTXCID60124211
Benzoic acid, 4-amino-, hydrazide (9CI)
226-324-4
inchi=1/c7h9n3o/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4h,8-9h2,(h,10,11)
wpbzmcgpfhzrhj-uhfffaoysa-n
4-Aminobenzoic hydrazide
MFCD00007606
CHEMBL2170241
Myeloperoxidase Inhibitor-I
4-Aminobenzoylhydrazide
p-Aminobenzohydrazide
p-amino benzhydrazide
4NPhCON2
4-Aminobenzohydrazide #
4-Aminobenzoyl hydrazide
WLN: ZNUYQR DZ
Myeloperoxidase Inhibitor 1
SCHEMBL328628
4-Aminobenzoic acid, hydrazide
NSC640
4-Aminobenzoic hydrazide, 95%
NSC-640
CHEBI:233355
HMS3741K15
ALBB-014057
HY-B0880
BBL003523
BDBM50396407
s9874
STK075152
AKOS000119698
FA59274
AS-57471
SY036768
DB-052348
A1211
CS-0012956
NS00032775
EN300-18128
H10753
Z57199627
F1796-0058