Skip to main content

4-Aminobutanol

ADVERTISEMENT
Identification
Molecular formula
C4H11NO
CAS number
3081-55-6
IUPAC name
4-aminobutan-1-ol
State
State

At room temperature, 4-aminobutanol is a liquid. It is known for its hygroscopic nature, meaning it can absorb moisture from the air.

Melting point (Celsius)
-70.00
Melting point (Kelvin)
203.15
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
89.14g/mol
Molar mass
89.1420g/mol
Density
0.9703g/cm3
Appearence

4-Aminobutanol is a colorless, viscous liquid. It is often characterized by its slightly amine-like odor, which is typical for amine-containing compounds.

Comment on solubility

Solubility of 4-Aminobutan-1-ol (C4H11NO)

4-Aminobutan-1-ol, also known as gamma-aminobutyric acid (GABA) in certain contexts due to its structural similarity, exhibits interesting solubility characteristics. This compound is a primary amine and a primary alcohol, which plays a significant role in its ability to dissolve in various solvents.

Solubility Properties:

  • Water Solubility: 4-Aminobutan-1-ol is highly soluble in water due to the presence of both amino (-NH2) and hydroxyl (-OH) functional groups, which can form strong hydrogen bonds with water molecules.
  • Alcohol Solubility: It is also soluble in lower alcohols like ethanol and methanol, further reinforcing its versatility as a solubilizing agent in organic solutions.
  • Limited Solubility in Organic Solvents: However, its solubility may decrease in non-polar organic solvents like hexane or benzene, which do not promote hydrogen bonding.

This compound's solubility can be summarized by the phrase: "Like dissolves like." Because of its polar nature, the enhanced solubility in polar solvents like water allows it to be effectively utilized in various biochemical applications. Understanding these solubility characteristics is crucial for industries ranging from pharmaceuticals to materials science.

Interesting facts

Interesting Facts About 4-Aminobutan-1-ol

4-Aminobutan-1-ol, commonly referred to as gamma-aminobutyric acid (GABA), plays a significant role in various biochemical processes and has garnered interest in both pharmaceutical and neuroscience fields.

Biological Importance

  • 4-Aminobutan-1-ol is known as an important neurotransmitter in the central nervous system.
  • It acts as an inhibitory neurotransmitter, helping to regulate neuronal excitability throughout the nervous system.
  • The compound is involved in reducing anxiety and has been studied for its potential therapeutic effects in conditions such as epilepsy, stress, and muscle relaxation.

Applications

  • Due to its calming effects, it is often explored in the formulation of various medications.
  • Research suggests potential uses in treating mood disorders and enhancing sleep quality.

Research Insights

Scientists continue to investigate the mechanisms of 4-aminobutan-1-ol and its analogs. Notably:

  • Studies indicate that administration of GABA can affect brain activity and may promote feelings of relaxation and well-being.
  • Interestingly, dietary sources of certain amino acids may influence the endogenous levels of this compound, impacting mood and cognitive function.

Conclusion

In summary, 4-aminobutan-1-ol is not merely a chemical compound, but a crucial player in the intricate symphony of neurotransmission. Its multifaceted nature as both a building block of life and a potential therapeutic agent makes it a key subject in contemporary scientific research.

Synonyms
4-Amino-1-butanol
13325-10-5
1-BUTANOL, 4-AMINO-
4-Aminobutanol
EINECS 236-364-4
4-Hydroxy-n-butylamine
AI3-28710
DTXSID70158027
DTXCID7080518
236-364-4
4-aminobutan-1-ol
4-hdyroxybutylamine
4-AMINO-BUTAN-1-OL
MFCD00008230
butane, 1-amino-4-hydroxy-
4-amino-butanol
4amino-1-butanol
4-Aminobutanol-1
4-hydroxybutylamine
4-amino 1-butanol
4-hydroxy-butylamine
4-amino-butan-1-o1
2-(aminoethyl)-ethanol
1-amino-4-hydroxybutane
N-(4-hydroxybutyl)amine
2-(2-aminoethyl)ethanol
SCHEMBL3116
SCHEMBL59334
SCHEMBL98350
4-Amino-1-butanol, 98%
H2N(CH2)4OH
NH2(CH2)4OH
SCHEMBL366957
SCHEMBL749869
H2NCH2(CH2)2CH2OH
SCHEMBL1828351
SCHEMBL3239181
SCHEMBL5934784
SCHEMBL6371716
SCHEMBL16632023
SCHEMBL22283793
SCHEMBL27390638
BCP18612
AC-034
BBL102556
STL556359
AKOS002670517
CS-W002041
FA49834
GS-3086
HY-W002041
SB83786
BP-30241
BP-31085
PD042491
SY001196
A1013
NS00024272
EN300-66126
4-Amino-n-butyl alcohol;4-Hydroxy-n-butylamine
Q63392130
F0001-3336
InChI=1/C4H11NO/c5-3-1-2-4-6/h6H,1-5H
1-Amino-4-butanol; 4-Amino-1-butanol; 4-Aminobutanol; 4-Hydroxy-1-butanamine; 4-Hydroxybutylamine; Butanolamine