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4-Aminobutanamide

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Identification
Molecular formula
C4H10N2O
CAS number
5416-84-0
IUPAC name
4-aminobutanamide
State
State
4-Aminobutanamide is typically found in solid state at room temperature and is stable under standard conditions.
Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
352.30
Boiling point (Kelvin)
625.45
General information
Molecular weight
88.14g/mol
Molar mass
88.1200g/mol
Density
1.1079g/cm3
Appearence

4-Aminobutanamide appears as a white crystalline solid. It does not have any distinct odor and features a smooth texture typical of many crystalline amides.

Comment on solubility

Solubility of 4-Aminobutanamide

4-Aminobutanamide, also known by its IUPAC name, is a fascinating compound when it comes to solubility. Its unique structure allows for interesting interactions with solvents.

General Solubility Characteristics:

  • Water Solubility: 4-Aminobutanamide is highly soluble in water due to the presence of the amide functional group, which can engage in hydrogen bonding with water molecules.
  • Organic Solvents: This compound is less soluble in non-polar organic solvents as they lack the ability to form hydrogen bonds, making polar solvents a more suitable choice.
  • Temperature Effects: Often, the solubility of such amides increases with temperature, which can be crucial for applications requiring higher concentrations.

As Pavlov's principle suggests, "Like dissolves like." This principle reinforces the idea that the polar nature of 4-aminobutanamide enhances its solubility in polar environments such as water.

In summary, 4-aminobutanamide exhibits excellent solubility in water and polar solvents while having limited solubility in nonpolar solvents, making it adaptable for various chemical applications.

Interesting facts

Interesting Facts About 4-Aminobutanamide

4-Aminobutanamide, also known as γ-aminobutyric acid amide, is an intriguing compound that occupies a unique niche in the world of organic chemistry. Here are some fascinating aspects of this compound:

  • Structural Significance: 4-Aminobutanamide possesses an amine functional group, which is pivotal for its biological activity. The presence of the amide bond makes it a precursor for many biologically active molecules.
  • Biological Relevance: This compound is a derivative of gamma-aminobutyric acid (GABA), which plays a significant role as a neurotransmitter in the central nervous system. GABA is crucial for inhibiting nerve transmission in the brain, thus, 4-aminobutanamide is garnering attention for its potential neuroprotective effects.
  • Applications: Due to its properties, 4-aminobutanamide is explored in various fields, including pharmaceuticals and biochemistry. Its study may lead to the development of new therapeutic agents for treating neurological disorders.
  • Synthetic Pathways: Methods for synthesizing 4-aminobutanamide include reductive amination and other techniques that highlight the versatility of organic synthesis. This opens doors for chemists to design compounds with interesting properties tailored for specific applications.
  • Research Horizons: Ongoing research is focusing on the potential of this compound in fields such as drug discovery and medicinal chemistry. It’s fascinating to see how modifications to simple organic frameworks can lead to innovative solutions in healthcare.

As researchers continue to explore the bonding, reactivity, and biological implications of 4-aminobutanamide, its contributions to the understanding of neurotransmission and potential therapeutic uses remain a vibrant area of study.

Synonyms
4-aminobutanamide
3251-08-9
4-Aminobutyramide
Butanamide, 4-amino-
gamma-Aminobutyric acid amide
gamma-aminobutyramide
GABA amide
Gabamide
BUTYRAMIDE, 4-AMINO-
EINECS 221-836-4
BRN 2037579
DQN3YXP96S
4-amino butyric acid amide
SCHEMBL3105
Butanamide, 4-amino- (9CI)
CHEMBL1199935
DTXSID80186235
ALBB-023443
butanamide, 4-amino-, hydrochloride
AC5898
AKOS000182532
BS-12705
DB-295193
NS00045702
EN300-41028
10.14272/WCVPFJVXEXJFLB-UHFFFAOYSA-N
AB01000773-01
doi:10.14272/WCVPFJVXEXJFLB-UHFFFAOYSA-N
A1-03399