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4-Aminobutanethiol

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Identification
Molecular formula
C4H11NS
CAS number
4471-40-7
IUPAC name
4-aminobutane-1-thiol
State
State

4-Aminobutanethiol is typically found in a liquid state at room temperature. Its liquid form is due to the balance of the alkyl chain and the presence of both an amine and a thiol group.

Melting point (Celsius)
-15.00
Melting point (Kelvin)
258.15
Boiling point (Celsius)
178.00
Boiling point (Kelvin)
451.15
General information
Molecular weight
105.20g/mol
Molar mass
105.2010g/mol
Density
0.9840g/cm3
Appearence

4-Aminobutanethiol typically appears as a clear to slightly yellowish liquid. It has a distinct odor that can be described as unpleasant or reminiscent of a sulfur compound. Due to the thiol group, it can have a slightly oily consistency.

Comment on solubility

Solubility of 4-aminobutane-1-thiol

4-aminobutane-1-thiol, also known as butanethiol or 1-amino-4-mercaptobutane, exhibits interesting solubility characteristics that are worth exploring.

This compound is relatively soluble in water due to its ability to form hydrogen bonds, attributed to the presence of both the amino group (-NH2) and the thiol group (-SH). The polar nature of these functional groups enhances its solubility in aqueous solutions.

Factors Influencing Solubility:

  • Polarity: The amino and thiol groups impart polarity to the molecule, facilitating its interaction with water molecules.
  • Molecular Size: The relatively small size of the 4-aminobutane-1-thiol compound allows for easy penetration and distribution in solvent media.
  • Temperature: Like many organic compounds, solubility may increase with temperature, allowing for more effective dissolution.

In summary, the solubility of 4-aminobutane-1-thiol in water can be described as favorable due to its polar functional groups. Thus, one could say that it is distinctly soluble in water, making it accessible for various applications in both organic chemistry and biochemistry.

Interesting facts

Interesting Facts about 4-Aminobutane-1-thiol

4-Aminobutane-1-thiol, also known by its IUPAC name, is a fascinating compound that belongs to the class of amino thiols. This compound has several noteworthy features that make it significant in both research and application:

  • Structure and Functionality: 4-Aminobutane-1-thiol features a primary amine group and a thiol group, which gives it unique reactivity. This combination provides opportunities for forming various derivatives that can serve in multiple applications.
  • Biological Relevance: Compounds containing thiol groups, like 4-aminobutane-1-thiol, are often found in biological systems and can play critical roles in metabolism as well as cellular processes. Thiols are involved in redox reactions, influencing cellular aging and antioxidant defense mechanisms.
  • Applications in Synthesis: 4-Aminobutane-1-thiol is utilized in the synthesis of more complex molecules in organic chemistry. Its ability to provide nucleophilic sites allows it to participate in various chemical reactions, including alkylation and acylation, making it a valuable building block in medicinal chemistry.
  • Potential in Therapeutics: Research on thiol-containing compounds has shown promise in drug design. The unique properties of 4-aminobutane-1-thiol may lead to the development of new drugs, particularly in the field of neurochemistry where it could affect neurotransmission.

Moreover, its derivatives have been explored for potential uses in:

  1. Neurology: Investigating neuroprotective effects.
  2. Antioxidant formulations: Exploring its ability to neutralize free radicals.
  3. Bioconjugation: In studies related to the coupling of biomolecules for therapeutic purposes.

Overall, 4-aminobutane-1-thiol is not just a simple chemical; it is a bridge between fundamental chemistry and applications in health sciences and materials research. Its intricate structure and reactivity continue to be a topic of research and interest in scientific communities.

Synonyms
4-aminobutane-1-thiol
21100-03-8
1-BUTANETHIOL, 4-AMINO-
4-Amino-1-butanethiol
4-Mercaptobutylamine
BRN 1731413
DTXSID90175332
4-04-00-01718 (Beilstein Handbook Reference)
RefChem:430860
DTXCID0097823
826-396-2
SCHEMBL62590
SCHEMBL5857639
SCHEMBL28098044
MFCD01741155
AKOS006346778
AT25915
FA170816
SY313724
EN300-151444