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Amiloride

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Identification
Molecular formula
C6H8ClN7O
CAS number
2609-46-3
IUPAC name
4-[[amino(guanidino)methylene]amino]-N-butyl-benzamide
State
State

Amiloride is typically found as a solid at room temperature. In its common pharmaceutical or laboratory form, it is a powder, making it easy to handle and process for various applications.

Melting point (Celsius)
279.00
Melting point (Kelvin)
552.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
229.25g/mol
Molar mass
229.2450g/mol
Density
1.2220g/cm3
Appearence

Amiloride typically appears as a white to pale yellow powder that is odorless. Its color may vary slightly depending on the purity and form but is generally observed as a solid that can be made into a more fine particulate or crystalline powder.

Comment on solubility

Solubility of 4-[[amino(guanidino)methylene]amino]-N-butyl-benzamide

The solubility of 4-[[amino(guanidino)methylene]amino]-N-butyl-benzamide can be characterized by several key factors:

  • Polarity: This compound features both hydrophilic (polar) and hydrophobic (non-polar) regions, which typically influences its solubility in different solvents.
  • Solvent Interaction: Due to the presence of amino and guanidino functional groups, it may exhibit better solubility in polar solvents such as water, compared to non-polar solvents.
  • Temperature Effect: As with many organic compounds, increased temperature may enhance its solubility in a given solvent.

However, the exact solubility behavior can significantly depend on specific conditions such as pH, the presence of salts, and other solubilizing agents. The complex structure suggests that while it may be soluble in aqueous solutions, its solubility could be limited under certain conditions. It is also important to consider that solubility can vary based on concentration and temperature.

In summary, the solubility of 4-[[amino(guanidino)methylene]amino]-N-butyl-benzamide is an intricate topic that emphasizes the importance of structural composition and external conditions. Conducting empirical solubility tests is recommended for precise determination.

Interesting facts

Interesting Facts about 4-[[amino(guanidino)methylene]amino]-N-butyl-benzamide

This intriguing compound, known for its complex structure, exhibits properties that make it a subject of interest in the realm of medicinal chemistry. It belongs to a class of molecules that can exhibit significant biological activity, particularly in the fields of pharmacology and biochemistry. Here are some fascinating aspects of this compound:

  • Biological Relevance: The guanidino group in the structure is often associated with biological activity, particularly in modifying enzyme functions and influencing metabolic pathways.
  • Potential Therapeutic Applications: Compounds like this one are being studied for their potential use as therapeutics in treating various diseases, including cancers and metabolic disorders.
  • Synthesis Interest: The synthetic pathways developed for creating such compounds can also lead to the discovery of new methodologies in organic synthesis, providing opportunities to explore different reaction mechanisms.
  • Structure-Activity Relationship (SAR): This compound provides a good case study for evaluating how modifications to the amino and guanidino groups alter biological activity and pharmacological effects.

As a student or scientist, delving into such compounds allows one to:

  • Unlock new insights into the structure-activity relationship of similar biochemical entities.
  • Engage in interdisciplinary research that combines organic chemistry with biological applications.
  • Appreciate the intricate balance between molecular structure and its implications in health and disease.

In conclusion, studying 4-[[amino(guanidino)methylene]amino]-N-butyl-benzamide opens doors to understanding the delicate interplay between chemistry and biology, making it an essential compound in the ongoing quest for innovative therapeutic solutions.