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Guanabenz

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Identification
Molecular formula
C8H8BrCl
CAS number
5051-62-7
IUPAC name
4-[[amino(guanidino)methylene]amino]-N-methyl-benzamide
State
State

Guanabenz is in a solid state at room temperature.

Melting point (Celsius)
212.50
Melting point (Kelvin)
485.65
Boiling point (Celsius)
359.00
Boiling point (Kelvin)
632.15
General information
Molecular weight
249.30g/mol
Molar mass
249.2970g/mol
Density
1.2000g/cm3
Appearence

Guanabenz typically appears as a white to off-white crystalline powder. It is usually odorless and stable under standard conditions.

Comment on solubility

Solubility of 4-[[amino(guanidino)methylene]amino]-N-methyl-benzamide

The solubility of 4-[[amino(guanidino)methylene]amino]-N-methyl-benzamide in various solvents often varies considerably. This compound, being an organic molecule with complex functional groups, exhibits distinct solubility characteristics:

  • Polar Solvents: It is generally soluble in polar solvents such as water and methanol due to hydrogen bonding capabilities of the amino and guanidino groups.
  • Non-Polar Solvents: The compound may show limited solubility in non-polar solvents like hexane or chloroform, as its structure is designed to interact more favorably with polar environments.
  • pH Dependency: Its solubility can also be affected by pH levels; it can have increased solubility in acidic or basic environments, depending on the protonation state of the amino groups.
  • Temperature Effects: An increase in temperature often enhances solubility for many organic compounds, and this is likely applicable here as well.

As with many compounds, understanding the solubility of 4-[[amino(guanidino)methylene]amino]-N-methyl-benzamide is crucial for its applications. It is essential to consider the potential solubility in different environments to optimize usage in chemical reactions or biological systems. As the saying goes, "Like dissolves like," emphasizing the importance of matching the polarity of the solvent with that of the solute.

Interesting facts

Interesting Facts about 4-[[amino(guanidino)methylene]amino]-N-methyl-benzamide

This fascinating compound, known as 4-[[amino(guanidino)methylene]amino]-N-methyl-benzamide, has piqued the interest of researchers due to its intriguing structural properties and potential applications. Here are some noteworthy aspects:

  • Bioactivity: This compound has shown potential in various biological applications, particularly in fields such as biochemistry and medicinal chemistry. Its unique guanidino functionality might play a crucial role in membrane permeability and receptor binding, making it an exciting candidate for drug development.
  • Synthetic Routes: The synthesis of this compound can involve multiple steps, which often includes reactions such as amination and guanidination. Researchers are continuously exploring more efficient synthetic pathways, contributing to the overall field of organic chemistry.
  • Structure-Activity Relationship (SAR): Understanding how different functional groups in compounds like this one affect their biological activity is a key area of research. This compound's ability to modify biological responses could lead to significant advancements in therapeutic agents.
  • Research Applications: The compound becomes particularly interesting in the study of enzyme inhibitors and anti-cancer activities. Its guanidino group, a characteristic feature, is often found in biologically active molecules, implicating its importance in pharmacological studies.
  • Potential of N-methylation: The N-methyl modification in this compound can drastically alter its pharmacokinetic properties, potentially enhancing its bioavailability and stability. This aspect opens avenues for designing more effective therapeutics.

As one delves deeper into the chemical universe, compounds like 4-[[amino(guanidino)methylene]amino]-N-methyl-benzamide serve as reminders of the intricate relationships between chemistry and biology. The exploration of such compounds can spark groundbreaking discoveries that can impact various health sciences.