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Benzamidine

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Identification
Molecular formula
C7H8N2
CAS number
140-28-3
IUPAC name
4-[[amino(guanidino)methylene]amino]-N,N-dibutyl-benzamide
State
State

Benzamidine is typically a solid at room temperature.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
119.15g/mol
Molar mass
119.1490g/mol
Density
1.1290g/cm3
Appearence

Benzamidine appears as a white crystalline solid. It is relatively stable and is typically found in its hydrochloride salt form to enhance solubility and stability.

Comment on solubility

Solubility of 4-[[amino(guanidino)methylene]amino]-N,N-dibutyl-benzamide

The solubility of 4-[[amino(guanidino)methylene]amino]-N,N-dibutyl-benzamide in various solvents showcases its unique chemical properties. Here are some key considerations:

  • Polar Solvents: Compounds containing amine and guanidine functional groups often exhibit significant solubility in polar solvents like water, due to the ability to form hydrogen bonds.
  • Non-Polar Solvents: In contrast, this compound may show limited solubility in non-polar solvents like hexane or toluene, as its structure is primarily hydrophilic because of the presence of multiple functional groups.
  • pH Dependence: The solubility might also be pH-dependent, where increased solubility occurs at varying pH levels that can affect the protonation state of the guanidino group.
  • Temperature Influence: Temperature can affect solubility; generally, higher temperatures lead to increased solubility for many organic compounds.

In summary, the solubility of this compound is influenced by its polar functional groups, the nature of the solvent, and environmental factors such as temperature and pH. Thus, considerable care should be taken when assessing and selecting solvents for its use in various applications.

Interesting facts

Interesting Facts about 4-[[amino(guanidino)methylene]amino]-N,N-dibutyl-benzamide

This compound, known for its complex structure, holds significant potential in medicinal chemistry and biological research. It is intriguing how a single molecule can serve various applications due to its functional groups and the overall configuration.

Key Features

  • Functional Diversity: The presence of both guanidine and amide functional groups within the molecule enhances its chemical reactivity, allowing it to participate in a variety of biological processes.
  • Potential Therapeutic Uses: 4-[[amino(guanidino)methylene]amino]-N,N-dibutyl-benzamide could serve as a scaffold for developing new drugs, particularly targeting certain diseases where guanidine derivatives have been found beneficial.
  • Role in Biochemistry: The guanidine group is a strong base and can influence the pH sensitivity of the compound, making it relevant in studies concerning enzyme activity and protein interactions.

Scientific Insights

Research into compounds like this one showcases the beauty of chemistry in designing molecules that possess unique properties. As stated by chemist Thomas C. Bruice, “Understanding the interactions within a molecule can lead to breakthroughs in medicine.” The intricate nature of this compound allows scientists to explore and understand these interactions better.

Furthermore, compounds with similar structures often exhibit interesting pharmacological profiles, ranging from antiviral to anticancer activities. This opens up a fascinating dialogue regarding the potential of 4-[[amino(guanidino)methylene]amino]-N,N-dibutyl-benzamide in drug discovery and development.

Conclusion

In summary, 4-[[amino(guanidino)methylene]amino]-N,N-dibutyl-benzamide represents not just a chemical entity, but also a stepping stone towards understanding more about compound interactions in biological systems. Its unique structure and properties make it an exciting subject for ongoing research in chemistry and biomedicine.