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Pirfenidone

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Identification
Molecular formula
C12H11NO2
CAS number
53179-13-8
IUPAC name
[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl dihydrogen phosphate
State
State

At room temperature, pirfenidone is found in a solid state. It is characterized as a crystalline powder, which is stable and can be handled safely under normal conditions.

Melting point (Celsius)
131.00
Melting point (Kelvin)
404.00
Boiling point (Celsius)
490.00
Boiling point (Kelvin)
763.00
General information
Molecular weight
185.22g/mol
Molar mass
185.2210g/mol
Density
1.5000g/cm3
Appearence

Pirfenidone typically appears as a white or off-white crystalline solid substance. It is known for its purity and consistency when synthesized for pharmaceutical use.

Comment on solubility

Solubility of [4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl dihydrogen phosphate

The solubility of the compound [4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl dihydrogen phosphate (C12H11NO2) can be influenced by several key factors:

  • Polarity: This compound contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) functional groups, which can significantly affect its ability to dissolve in water.
  • pH Level: Being a phosphate compound, its solubility may vary with changes in pH. Generally, phosphate esters tend to be more soluble in acidic conditions.
  • Temperature: Like many compounds, solubility typically increases with temperature. Thus, higher temperatures may enhance the solubility of this compound in aqueous solutions.
  • Presence of Other Solvents: The solubility can also change when mixed with other solvents or in the presence of various ions, which may interact with the compound differently.

In summary, while specific solubility data may vary, understanding these influencing factors is crucial. As a general insight, compounds with functional groups like amino and hydroxyl typically exhibit better solubility in polar solvents. Therefore, for [4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl dihydrogen phosphate, one might expect variable solubility patterns depending on the specific conditions outlined above.

Interesting facts

Interesting Facts about [4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl dihydrogen phosphate

[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl dihydrogen phosphate is a fascinating compound that belongs to the class of organophosphates. These compounds are crucial in various applications due to their unique properties and functionalities.

Key Features:

  • Biological Relevance: This compound is known for its role in biochemical pathways, serving as an important precursor in the synthesis of biologically active molecules.
  • Enzyme Inhibition: It can interact with enzymes, influencing metabolic processes and potentially serving as a lead compound for the development of therapeutic agents.
  • Versatile Applications: Apart from its biochemical roles, it can be leveraged in agricultural practices, where organophosphate compounds often function as pesticides and herbicides.

The presence of both an amine and a hydroxy group enhances the compound's reactivity, making it an interesting subject of study for synthetic chemists. The structure exhibits a pyridine ring, benefiting from the aromatic stability while providing sites for further chemical modifications.

A Quote to Consider:

As Albert Einstein once said, "Everything should be made as simple as possible, but no simpler." This philosophy often guides chemists as they explore complex compounds like [4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl dihydrogen phosphate, seeking to unravel their mysteries and optimize their applications.

In summary, this compound represents a bridge between organic chemistry and biochemistry, showcasing the interconnectedness of various scientific fields. Further research may reveal even more about its utility and behavior, stimulating curiosity within the scientific community.

Synonyms
pyridoxamine phosphate
PYRIDOXAMINE-5'-PHOSPHATE
529-96-4
pyridoxamine 5'-phosphate
Pyridoxamine 5-phosphate
Pyridoxamine-P
Pyridoxamine phosphate [JAN]
[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methyl dihydrogen phosphate
Pyridoxamine, dihydrogen phosphate
AMMONIUM FERRIC CHLORIDE
Pyridoxamine, 3-(dihydrogen phosphate)
BRN 0233653
EINECS 208-471-6
4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE
Q05R77UO7P
Pyridoxamine 5'-phosphoric acid
DTXSID3046825
CHEBI:18335
pyridoxamine-5-phosphate
PYRIDOXAMINE PHOSPHATE ANHYDROUS
4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol alpha-(dihydrogen phosphate)
Pyridoxamine 5-phosphoric acid
16774-56-4
DTXCID1026825
4-22-00-06065 (Beilstein Handbook Reference)
4-Aminomethyl-3-hydroxy-2-methyl-5-((phosphonooxy)methyl)pyridine dihydrate
3-Pyridinemethanol, 4-(aminomethyl)-5-hydroxy-6-methyl-, alpha-(dihydrogen phosphate)
pyridoxamine 5'-(dihydrogen phosphate)
PYRIDOXAMINE PHOSPHATE [WHO-DD]
PYRIDOXAMINE 5'-PHOSPHATE [MI]
NCGC00181045-01
Pyridoxamine, dihydrogen phosphate (7CI)
(4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate
Pyridoxamine 5 inverted exclamation marka-phosphate
Pyridoxamine Phosphate (JAN)
{[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid
4-AMINOMETHYL-3-HYDROXY-2-METHYL-5-((PHOSPHONOOXY)METHYL)PYRIDINE
UNII-Q05R77UO7P
((4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl)methoxy)phosphonic acid
1zc9
bmse000131
529-96-4, anhydride
SCHEMBL43832
Pyridoxamine 5a(2)-phosphate
CHEMBL1235353
HY-B1746
Tox21_112693
MFCD00023504
DB02142
NCGC00181045-02
CAS-529-96-4
DB-052230
CS-0013766
NS00014914
C00647
G77475
Pyridoxamine-5'-phosphate, >=98.0% (HPLC)
SBI-0654078.0001
Pyridoxamine-5 inverted exclamation marka-phosphate
Q27093205
4-Aminomethyl-5-hydroxy-6-methyl-3-pyridylmethyl phosphate
[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl dihydrogen phosphate
3-Pyridinemethanol, 4-(aminomethyl)-5-hydroxy-6-methyl-, 3-(dihydrogen phosphate)
208-471-6
PZP