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Clomipramine Hydrochloride

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Identification
Molecular formula
C19H23ClN2O2
CAS number
303-49-1
IUPAC name
(4-azaniumylpiperazin-1-yl)ammonium;3-(2-chlorophenyl)prop-2-enoate
State
State

At room temperature, clomipramine hydrochloride is a solid. It is typically available in the form of tablets or capsules for medicinal use.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
314.84g/mol
Molar mass
314.8300g/mol
Density
1.3000g/cm3
Appearence

Clomipramine hydrochloride appears as a white to off-white crystalline powder. It is generally used in its hydrochloride salt form due to its increased solubility in water.

Comment on solubility

Solubility of (4-azaniumylpiperazin-1-yl)ammonium; 3-(2-chlorophenyl)prop-2-enoate

The solubility of the compound (4-azaniumylpiperazin-1-yl)ammonium; 3-(2-chlorophenyl)prop-2-enoate is influenced by several factors that characterize both its organic and ionic components.

Factors Influencing Solubility

  • Ionic Nature: The presence of ammonium groups suggests that this compound may readily dissolve in polar solvents, particularly water, due to strong ion-dipole interactions.
  • Hydrophobic Interactions: The chloro group in the phenyl moiety and the alkene unit may create regions of hydrophobicity, potentially reducing solubility in aqueous environments.
  • pH Dependency: Given its ammonium cation, the solubility may also be pH-dependent, being more soluble in acidic conditions where the ammonium form predominates.

Overall, one might expect this compound to exhibit a mixed solubility behavior:

  • High solubility in polar solvents such as water and alcohols.
  • Lower solubility in nonpolar solvents due to its hydrophobic sections.

In summary, while the ionic functionalities provide a pathway for solubility in polar solvents, the presence of hydrophobic groups could hinder complete dissolution, making the solubility characteristics of this compound particularly intriguing.

Interesting facts

Exploring (4-azaniumylpiperazin-1-yl)ammonium;3-(2-chlorophenyl)prop-2-enoate

(4-azaniumylpiperazin-1-yl)ammonium;3-(2-chlorophenyl)prop-2-enoate is a compound that showcases the intricate structures found in organic chemistry. Known for being a **cationic compound**, it plays a significant role in various fields, including pharmaceuticals and organic synthesis. Let us dive into some fascinating aspects of this compound:

Key Highlights:

  • Multi-functional Utility: This compound serves as a building block in the synthesis of various therapeutic agents due to its charged piperazine moiety, contributing to its interaction with biological systems.
  • Chemical Reactivity: Its ability to participate in numerous chemical reactions, such as nucleophilic substitutions and addition reactions, makes it a valuable participant in organic synthesis.
  • Biological Implications: The presence of a chlorophenyl group enhances its pharmacological potential, being linked to various biological activities including antimicrobial and anticancer properties.
  • Aesthetic Symmetry: The structure exhibits notable symmetry with the arrangement of its constituent groups, which not only contributes to its reactivity but also to its potential interactions with cellular targets.

In the context of drug design, this compound offers a promising scaffold. According to research, cationic compounds like this one can interact with negatively charged cellular components, enhancing their therapeutic efficacy. As a future scientist or chemistry enthusiast might say, "Understanding compounds like (4-azaniumylpiperazin-1-yl)ammonium;3-(2-chlorophenyl)prop-2-enoate opens the door to innovative therapeutic strategies."

Continued research into its applications and synthetic pathways could yield profound insights into its utility and efficiency in drug formulation, marking a significant step forward in medicinal chemistry.