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4-(Azetidin-3-yl)aniline

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Identification
Molecular formula
C9H12N2
CAS number
106500-00-9
IUPAC name
4-(azetidin-3-yl)aniline
State
State
At room temperature, 4-(azetidin-3-yl)aniline is typically in a solid state. It is stable but should be stored under appropriate conditions as recommended by SDS to prevent any degradation or reaction with environmental factors.
Melting point (Celsius)
96.00
Melting point (Kelvin)
369.15
Boiling point (Celsius)
284.50
Boiling point (Kelvin)
557.65
General information
Molecular weight
162.22g/mol
Molar mass
162.2150g/mol
Density
1.1200g/cm3
Appearence

4-(Azetidin-3-yl)aniline typically appears as a crystalline solid. It can vary in color from white to off-white depending on the degree of purity and the specific conditions of synthesis. The compound is usually synthesized in laboratories where it is used for various chemical reactions.

Comment on solubility

Solubility of 4-(azetidin-3-yl)aniline

4-(azetidin-3-yl)aniline, a compound with the formula C10H12N2, exhibits distinct solubility characteristics that are important for various applications. Understanding the solubility of this compound can be summarized by the following points:

  • Polarity: Due to the presence of both aromatic and amine functional groups, 4-(azetidin-3-yl)aniline is a polar compound. This polarity affects its solubility in different solvents.
  • Solvent Compatibility: It is generally more soluble in polar solvents such as water, methanol, and ethanol. However, its solubility diminishes in non-polar solvents like hexane and toluene.
  • Temperature Influence: As with many compounds, increasing temperature often enhances the solubility of 4-(azetidin-3-yl)aniline in solvents, making higher temperatures advantageous for dissolving this compound.
  • pH Sensitivity: The solubility can also be affected by the pH of the solution. In acidic conditions, the amine group may be protonated, increasing its solubility in water.

In summary, "solubility is not a fixed property" and can be influenced by various factors including solvent polarity, temperature, and pH. When working with 4-(azetidin-3-yl)aniline, it is crucial to consider these aspects to achieve optimal results in applications such as synthesis, drug formulation, and chemical analysis.

Interesting facts

Exploring 4-(azetidin-3-yl)aniline

4-(azetidin-3-yl)aniline, a compound of interest in the realm of organic chemistry, offers unique structural features and potential applications. Here are some fascinating aspects to consider:

  • Structural Versatility: The presence of an azetidine ring, which is a four-membered cyclic amine, adds to the compound's reactivity and versatility in chemical synthesis. Such structures are known for their ability to serve as building blocks for more complex molecules.
  • Pharmaceutical Relevance: Compounds containing both aromatic amines and azetidine moieties are often investigated in drug discovery. They can exhibit a range of biological activities, making them valuable in medicinal chemistry research.
  • Synthetic Pathways: The synthesis of 4-(azetidin-3-yl)aniline can involve various methods, such as nucleophilic substitutions or cyclization reactions, which highlight the importance of organic synthetic techniques in producing complex nitrogen-containing compounds.
  • Potential for Neoteric Applications: Given the increasing interest in exploring compounds that exhibit antimicrobial, anti-inflammatory, or anticancer properties, 4-(azetidin-3-yl)aniline could be a candidate for further research in these areas.
  • Studies and Developments: Ongoing studies may reveal additional properties and uses for this compound, encouraging collaboration among chemists, biologists, and pharmacologists to unveil its potential.

As a compound that bridges multiple domains of chemistry, 4-(azetidin-3-yl)aniline represents the intersection where synthetic innovation meets biological significance. Its study not only expands our understanding of nitrogen heterocycles but also opens doors to future discoveries in the fields of medicinal and agricultural chemistry.

Synonyms
7215-04-5
p-(3-Azetidinyl)aniline
3-(p-Aminophenyl)azetidine
Aniline, p-(3-azetidinyl)-
AZETIDINE, 3-(p-AMINOPHENYL)-
L 2409
BRN 0473126
DTXSID10222473
5-22-09-00466 (Beilstein Handbook Reference)
DTXCID10144964
4-(azetidin-3-yl)aniline
SCHEMBL520532
GS0575
AKOS006342222
F95560
EN300-6772636