Interesting Facts about 4-Azido-5-(2-ethoxyethyl)-6-phenyl-pyrimidin-2-amine
4-Azido-5-(2-ethoxyethyl)-6-phenyl-pyrimidin-2-amine is a fascinating compound within the realm of medicinal chemistry and pharmaceutical research. Its structure and properties make it a subject of great interest among scientists.
Key Features
- Azole Group: The presence of the azido group (–N₃) is notable, as it can serve as a useful handle for further chemical modifications. This feature can make the compound reactive in certain conditions, paving the way for various synthetic applications.
- Pyrimidine Core: The pyrimidine ring is significant in many biological systems and often features in nucleic acids. It's a common scaffold for drug discovery, leading to important derivatives used in therapeutics.
- Oncology Potential: The ability of compounds like this one to inhibit specific biological pathways makes them candidates for cancer research. Their unique structure could allow for selective targeting of cancer cells.
- Pharmacophore:**: The combination of the ethoxyethyl and phenyl groups influences the compound's lipophilicity and solubility, potentially enhancing its pharmacological properties.
As a chemist or student diving into the world of complex molecules, one cannot overlook the versatility that compounds like 4-azido-5-(2-ethoxyethyl)-6-phenyl-pyrimidin-2-amine offer. They illustrate the delicate balance of reactivity and stability in target-oriented synthesis. As noted in a recent study, such compounds are "at the forefront of revolutionary treatments."
A deeper understanding of their mechanisms can lead to breakthroughs in personalized medicine, making them invaluable in the pharmaceutical landscape.
Solubility of 4-azido-5-(2-ethoxyethyl)-6-phenyl-pyrimidin-2-amine
The solubility of 4-azido-5-(2-ethoxyethyl)-6-phenyl-pyrimidin-2-amine (C14H16N6O) can be an intriguing subject, given its molecular structure and functional groups. Understanding its solubility profile is essential for applications in pharmaceutical chemistry and material science.
Key aspects to consider regarding its solubility include:
In the context of solubility, it is often observed that:
In summary, while the specific solubility data for 4-azido-5-(2-ethoxyethyl)-6-phenyl-pyrimidin-2-amine is not readily available, one can infer its behavior based on its molecular structure and functional groups. As always, experimental validation is necessary to confirm the solubility characteristics in practical applications.