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Indoprofen

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Identification
Molecular formula
C19H22N2O4
CAS number
31842-01-0
IUPAC name
4-benzamido-5-(dipropylamino)-5-oxo-pentanoic acid
State
State

At room temperature, Indoprofen is a solid substance. It can exist in the crystalline form as mentioned in its appearance.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
506.50
Boiling point (Kelvin)
779.65
General information
Molecular weight
333.39g/mol
Molar mass
333.4170g/mol
Density
1.1300g/cm3
Appearence

Indoprofen appears as a white to off-white crystalline powder. It is slightly soluble in water and more soluble in organic solvents such as ethanol and methanol.

Comment on solubility

Solubility of 4-benzamido-5-(dipropylamino)-5-oxo-pentanoic acid

The solubility of 4-benzamido-5-(dipropylamino)-5-oxo-pentanoic acid (C19H22N2O4), a complex organic compound, can be influenced by several factors. Given its molecular structure, this compound exhibits unique solubility characteristics, which can generally be summarized as follows:

  • Polar and Non-Polar Interactions: The presence of both polar functional groups, such as the amido and oxo groups, and non-polar hydrocarbon chains (dipropyl) suggests that the compound may interact favorably with both polar and non-polar solvents.
  • Solvent Compatibility: It may demonstrate better solubility in organic solvents like ethanol, methanol, or acetonitrile due to its hydrophobic regions, though it might have limited solubility in water.
  • pH Dependence: The ionic state of the compound can change depending on the pH, potentially enhancing solubility in acidic or alkaline conditions, given the presence of carboxylic acid functionalities.

Overall, while definitive solubility data may vary, it is likely that 4-benzamido-5-(dipropylamino)-5-oxo-pentanoic acid exhibits increased solubility in organic solvents as opposed to aqueous solutions. Understanding these solubility properties is vital for applications in pharmaceuticals and chemical research.

Interesting facts

Exploring 4-benzamido-5-(dipropylamino)-5-oxo-pentanoic acid

4-benzamido-5-(dipropylamino)-5-oxo-pentanoic acid is a fascinating compound with intriguing properties and potential applications. Here are some interesting facts about this chemical:

  • Pharmaceutical Relevance: This compound may play a significant role in the pharmaceutical industry, particularly in drug design and development. Its unique structure is thought to contribute to various biochemical interactions.
  • Structure and Function: The presence of the benzamido group enhances its ability to interact with biological systems, potentially improving its efficacy as a therapeutic agent.
  • Biological Activity: Research suggests that compounds similar to this one can exhibit notable biological activity, which could include antimicrobial or anti-inflammatory properties.
  • Amine Component: The dipropylamino part of the molecule is particularly noteworthy as it can affect the compound's solubility and permeability, influencing how the body absorbs and metabolizes it.
  • Synthesis Considerations: The synthesis of this compound involves multiple steps and careful control of reaction conditions to ensure the desired functional groups are preserved.

In summary, 4-benzamido-5-(dipropylamino)-5-oxo-pentanoic acid is not just a chemical compound, but a potential catalyst for medical advancement. As scientists continue to explore its properties, it could lead towards new therapies and a deeper understanding of biochemical processes.

Synonyms
proglumide
6620-60-6
4-benzamido-5-(dipropylamino)-5-oxopentanoic acid
Binoside
Xylamide
Nulsa
Gastrotopic
Midelid
Ulcutin
dl-proglumide
Milid
Proglumida
Proglumidum
Milide
Xyde
Pentanoic acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-
Promid
Proglumidum [INN-Latin]
Proglumida [INN-Spanish]
Promide (parasympatholytic)
W-5219
CR 242
Xylamide (gastroprotective agent)
EINECS 229-567-4
242 DL
CR-242
W 5219
NSC-757841
BRN 4151696
EPL8W5565D
Nulsa (TN)
DTXSID7023516
CHEBI:32058
Pentanoic acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-, (+-)-
4-(benzoylamino)-5-(dipropylamino)-5-oxopentanoic acid
Proglumide [USAN:INN:BAN:JAN]
PROGLUMIDE [MI]
PROGLUMIDE [INN]
PROGLUMIDE [JAN]
(+-)-4-Benzamido-N,N-dipropylglutaramic acid
PROGLUMIDE [USAN]
Glutaramic acid, 4-benzamido-N,N-dipropyl-, DL-
PROGLUMIDE [MART.]
PROGLUMIDE [WHO-DD]
CHEMBL316561
DTXCID003516
NSC 757841
Proglumidum (INN-Latin)
Proglumida (INN-Spanish)
PROGLUMIDE (MART.)
24485-90-3
Xilamide
SR-01000002970
UNII-EPL8W5565D
racemic proglumide
(RS)-proglumide
Proglumide,(S)
NCGC00016676-01
(+-)-proglumide
4-(Benzoylamino)-5-(dipropylamino)-5-oxo-pentanoic acid;DL-4-Benzamido-N,N-dipropylglutaramic acid;(+/-)-Proglumide
Prestwick_602
CAS-6620-60-6
MFCD00055071
Spectrum_001332
DL-4-benzamido-N,N-dipropylglutaramic acid
Prestwick0_000240
Prestwick1_000240
Prestwick2_000240
Prestwick3_000240
Spectrum2_001406
Spectrum3_001444
Spectrum4_000425
Spectrum5_001591
(+/-)-4-Benzamido-N,N-dipropylglutaramic acid
Lopac0_000832
SCHEMBL93339
BSPBio_000319
BSPBio_002907
GTPL893
KBioGR_000750
KBioSS_001812
MLS002154246
DivK1c_000684
SPECTRUM1501119
SPBio_001452
SPBio_002240
4-(Benzoylamino)-5-(dipropylamino)-5-oxovaleric acid
BPBio1_000351
Proglumide - Bio-X trade mark
Proglumide (JP17/USAN/INN)
SCHEMBL19994752
CHEBI:76266
HMS502C06
KBio1_000684
KBio2_001812
KBio2_004380
KBio2_006948
KBio3_002407
A02BX06
NINDS_000684
HMS1568P21
HMS1921F19
HMS2092D13
HMS2095P21
HMS2235B24
HMS3262H05
HMS3369D14
HMS3712P21
Pharmakon1600-01501119
HY-B1330
Tox21_110557
Tox21_500832
BDBM50014888
CCG-39024
NSC757841
Pentanoic acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-, (.+-.)-
AKOS015895810
Tox21_110557_1
AC-1274
CS-8029
DB13431
FP27175
KS-1212
LP00832
SDCCGSBI-0050809.P004
4-Benzamido-N,N-dipropylglutaramic acid
IDI1_000684
NCGC00015623-03
NCGC00015623-04
NCGC00015623-05
NCGC00015623-06
NCGC00015623-07
NCGC00015623-10
NCGC00015623-14
NCGC00094163-01
NCGC00094163-02
NCGC00094163-03
NCGC00094163-04
NCGC00261517-01
BP166197
DA-66886
SMR001233513
SBI-0050809.P003
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine
AB00052206
EU-0100832
M-001
NS00004778
N2-(phenylcarbonyl)-N,N-dipropyl-a-glutamine
4-Benzoylamino-4-dipropylcarbamoyl-butyric acid
D01818
G12126
rac-N(2)-benzoyl-N,N-dipropyl-alpha-glutamine
AB00052206_08
4-Benzoylamino-5-dipropylamino-5-oxopentanoic acid
N~2~-(phenylcarbonyl)-N,N-dipropyl-alpha-glutamine
Q7248362
SR-01000002970-2
SR-01000002970-4
SR-01000002970-7
BRD-A44863528-001-05-8
BRD-A44863528-001-08-2
BRD-A44863528-001-13-2
4-(Benzoylamino)-5-(dipropylamino)-5-oxo-pentanoic Acid
PENTANOIC ACID, 4-(BENZOYLAMINO)-5-(DIPROPYLAMINO)-5-OXO-, (+/-)-
229-567-4