Skip to main content

4-[bis(2-bromoethyl)amino]benzoic acid

ADVERTISEMENT
Identification
Molecular formula
C11H13Br2NO2
CAS number
10411-94-6
IUPAC name
4-[bis(2-bromoethyl)amino]benzoic acid
State
State

This compound is typically found in a solid state at room temperature.

Melting point (Celsius)
124.00
Melting point (Kelvin)
397.00
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.00
General information
Molecular weight
362.04g/mol
Molar mass
362.0600g/mol
Density
1.7900g/cm3
Appearence

This compound typically appears as a white to off-white solid powder. It is normally encountered in the form of crystalline material and is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 4-[bis(2-bromoethyl)amino]benzoic acid

4-[bis(2-bromoethyl)amino]benzoic acid is a compound that presents interesting solubility characteristics. It exhibits a moderate solubility profile that can be influenced by various factors:

  • Polarity: The presence of both the amino group and the carboxylic acid functional group contributes to its polar nature, which generally enhances its solubility in polar solvents.
  • Solvent Selection: This compound is typically soluble in solvents such as water, methanol, and ethanol due to hydrogen bonding capabilities. However, its solubility might be less favorable in nonpolar solvents such as hexane or toluene.
  • Concentration Effects: Solubility may also vary with concentration—at lower concentrations, the dissolution is more favorable, while saturation can hinder further solubilization.
  • Temperature: Temperature increases often lead to enhanced solubility, making it easier to dissolve at elevated temperatures.

In summary, the solubility of 4-[bis(2-bromoethyl)amino]benzoic acid is a multifaceted aspect that can be significantly influenced by its structural components and environmental conditions. Exploring its solubility behavior can provide deeper insights into its potential applications and interactions in various chemical contexts.

Interesting facts

Interesting Facts about 4-[bis(2-bromoethyl)amino]benzoic acid

4-[bis(2-bromoethyl)amino]benzoic acid, a fascinating member of the benzoic acid derivatives, presents a unique blend of functionalities that make it noteworthy in chemical research. Here are some intriguing aspects:

  • Versatile Applications: This compound is often explored in the realm of medicinal chemistry, especially in the development of pharmaceuticals targeting specific biological pathways. The presence of bromine atoms is particularly significant as they can enhance the biological activity of the compound.
  • Potential in Drug Design: Compounds with similar structures have been utilized for the design of anticancer agents and antimicrobial substances, where optimizing the 'bromoethyl' group might lead to improved efficacy and selectivity.
  • Reaction Mechanisms: The functional groups present in this compound allow for various chemical transformations, including nucleophilic substitutions and coupling reactions, making it an interesting subject for organic synthesis.
  • Insight into Chemical Properties: The introduction of the amino group enhances the compound's ability to form hydrogen bonds, which can significantly affect solubility and interaction with biological molecules.
  • Research Potential: Given the structural complexity, 4-[bis(2-bromoethyl)amino]benzoic acid serves as an excellent candidate for studies in structure-activity relationships (SAR), guiding future synthesis and modifications.

In summary, 4-[bis(2-bromoethyl)amino]benzoic acid is much more than a simple chemical compound; it stands at the crossroads of chemistry and pharmacology, offering vast potential for innovative applications in drug development and synthetic chemistry. As the world of pharmaceuticals continues to evolve, such compounds will undoubtedly play a role in shaping future discoveries.

Synonyms
BRN 2737221
BENZOIC ACID, p-(BIS(2-BROMOETHYL)AMINO)-
2045-18-3
p-(Bis(2-bromoethyl)amino)benzoic acid
DTXSID90174401
DTXCID1096892
4-[N,N-Bis(2-bromoethyl)amino]benzoic acid
SCHEMBL7460843
CHEMBL3246928
PDMWTJJWTBLAOZ-UHFFFAOYSA-N