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Amidotrizoic acid

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Identification
Molecular formula
C11H11I2NO2
CAS number
297-83-6
IUPAC name
4-[bis(2-iodoethyl)amino]benzoic acid
State
State

At room temperature, amidotrizoic acid is in a crystalline solid state. It is typically stable under standard conditions and is usually stored in airtight containers to protect it from moisture and light.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
541.97g/mol
Molar mass
541.9650g/mol
Density
2.4000g/cm3
Appearence

Amidotrizoic acid appears as a white to off-white crystalline powder. It may also appear as a slightly yellowish powder due to impurities and exposure to certain conditions.

Comment on solubility

Solubility of 4-[bis(2-iodoethyl)amino]benzoic acid

The solubility of 4-[bis(2-iodoethyl)amino]benzoic acid can be influenced by several factors, particularly its unique structure and functional groups. This compound contains both aromatic and amine functionalities, which can interact differently with solvents.

Key Points on Solubility:

  • Polar vs Non-Polar Solvents: Due to the presence of an amine group, 4-[bis(2-iodoethyl)amino]benzoic acid is likely to have better solubility in polar solvents such as water, alcohols, and certain organic solvents.
  • Hydrogen Bonding: The carboxylic acid functional group can participate in hydrogen bonding, which can aid in solubility in both polar and protic solvents.
  • Effect of Substituents: The presence of the iodoethyl groups may introduce steric hindrance, potentially impacting its solubility properties compared to simpler analogs.
  • Temperature Dependency: The solubility may increase with temperature, which is typical for many organic compounds.

In summary, while the exact solubility value can vary, it is important to note that the molecular interactions facilitated by the functional groups make 4-[bis(2-iodoethyl)amino]benzoic acid relatively more soluble in appropriate solvents. Experimentation under specific conditions is recommended for precise assessments.

Interesting facts

Interesting Facts About 4-[bis(2-iodoethyl)amino]benzoic Acid

4-[bis(2-iodoethyl)amino]benzoic acid is a fascinating compound noteworthy for its unique structure and potential applications. Here are some intriguing aspects of this chemical:

  • Structure and Functionality: This compound features a benzoic acid core, which is a common motif in organic chemistry. The bis(2-iodoethyl) substituents introduce powerful halogenated side chains that can enhance reactivity and binding affinity in biological systems.
  • Research Application: Compounds of this nature are often investigated for their properties in medicinal chemistry. The introduction of iodine atoms can influence the compound’s behavior in pharmaceutical applications, especially in areas like targeted drug delivery and imaging.
  • Biological Implications: The presence of the amino group in the structure indicates potential interactions with biological receptors, offering avenues for research in drug design aimed at diseases that require targeted therapies.
  • Material Science: The halogen groups, and in particular the iodine, often play a crucial role in the physical properties of polymers. This could be advantageous for creating advanced materials with desirable characteristics such as better thermal stability or chemical resistance.
  • Coordination Chemistry: Due to its amino group, 4-[bis(2-iodoethyl)amino]benzoic acid can act as a ligand in coordination chemistry, forming complex structures with various metal ions.

Overall, 4-[bis(2-iodoethyl)amino]benzoic acid exemplifies the intersection of organic synthesis and real-world application, pushing the boundaries of how we understand and utilize chemical compounds in both scientific research and practical innovations. As a reminder, the diversity within its structure opens pathways to explore further in various fields of science.

Synonyms
2045-13-8
BRN 2810539
BENZOIC ACID, p-(BIS(2-IODOETHYL)AMINO)-
p-(Bis(2-iodoethyl)amino)benzoic acid
DTXSID20174398
DTXCID2096889
4-[bis(2-iodoethyl)amino]benzoic acid
CHEMBL3246924