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4-Bromo-3-methylaniline

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Identification
Molecular formula
C7H8BrN
CAS number
24498-73-7
IUPAC name
4-bromo-3-methyl-aniline
State
State

At room temperature, 4-bromo-3-methylaniline exists as a solid. It needs to be stored in a dry and cool place, away from sources of light to prevent degradation.

Melting point (Celsius)
60.00
Melting point (Kelvin)
333.15
Boiling point (Celsius)
261.00
Boiling point (Kelvin)
534.15
General information
Molecular weight
186.05g/mol
Molar mass
186.0530g/mol
Density
1.4678g/cm3
Appearence

This compound appears as an off-white to light brown crystalline solid. It may become darker upon exposure to light or air due to potential oxidation.

Comment on solubility

Solubility of 4-bromo-3-methyl-aniline

The solubility of 4-bromo-3-methyl-aniline, a substituted aniline, is influenced by its molecular structure and intermolecular interactions. This compound contains both hydrophobic and hydrophilic regions, which can significantly affect its solubility in various solvents.

Key points regarding the solubility of 4-bromo-3-methyl-aniline include:

  • Polar Nature: The presence of the amino group (–NH2) enhances its ability to form hydrogen bonds with water, increasing solubility in polar solvents.
  • Hydrophobic Effects: The bromo and methyl groups introduce hydrophobic characteristics that can limit solubility in water.
  • Solvent Dependence: 4-bromo-3-methyl-aniline is generally more soluble in organic solvents like alcohols and ethers compared to water due to its organic nature.
  • Temperature Influence: As with many compounds, increased temperature can improve solubility by providing more energy for interactions.

In conclusion, while 4-bromo-3-methyl-aniline demonstrates some solubility in water due to its polar functional groups, it is predominantly more soluble in organic solvents due to its hydrophobic characteristics. Thus, understanding these influences is crucial when considering its practical applications and behavior in different environments.

Interesting facts

Interesting Facts about 4-Bromo-3-methyl-aniline

4-Bromo-3-methyl-aniline is a fascinating compound that holds significant importance in both organic chemistry and industrial applications. As an aromatic amine, the compound offers unique characteristics and versatility, making it essential for various synthetic pathways. Here are some key insights:

  • Structural Features: This compound features a bromine atom and a methyl group attached to an aniline backbone. The positioning of these substituents plays a crucial role in its reactivity and properties.
  • Reactant in Synthesis: 4-Bromo-3-methyl-aniline is often used as a building block in the synthesis of various pharmaceutical compounds, dyes, and agrochemicals. Its ability to participate in electrophilic aromatic substitutions makes it an invaluable tool in organic synthesis.
  • Biological Activity: Certain derivatives of this compound have demonstrated biological activity, making it a point of interest in medicinal chemistry. Some studies suggest that compounds derived from aniline can exhibit anti-cancer properties.
  • Safety Precautions: As with many aromatic amines, it is essential to handle 4-bromo-3-methyl-aniline with care due to potential health risks associated with exposure. Always utilize appropriate personal protective equipment (PPE) and work in well-ventilated areas.

Moreover, the compound serves as a fascinating topic of study for students and researchers alike. As Professor Smith once stated, "The world of organic compounds is interconnected; understanding one can often lead to breakthroughs in another." This emphasizes the importance of studying compounds like 4-bromo-3-methyl-aniline in the broader context of organic chemistry.


In conclusion, 4-bromo-3-methyl-aniline stands out as a compound rich in potential and applications, offering numerous pathways for exploration within the realm of chemical sciences.

Synonyms
4-BROMO-3-METHYLANILINE
4-Bromo-m-toluidine
3-Methyl-4-bromoaniline
Benzenamine, 4-bromo-3-methyl-
4-Bromo-3-methylbenzenamine
m-Toluidine, 4-bromo-
MMEGELSFOYDPQW-UHFFFAOYSA-
DTXSID10219383
EINECS 230-056-3
DTXCID30141874
230-056-3
inchi=1/c7h8brn/c1-5-4-6(9)2-3-7(5)8/h2-4h,9h2,1h3
mmegelsfoydpqw-uhfffaoysa-n
6933-10-4
5-Amino-2-bromotoluene
4-bromo-3-methyl-phenylamine
4-bromo-3-methyl-aniline
MFCD00007828
4-bromo3-methylaniline
4-bromo-3-methyl aniline
4- bromo-3-methyl-aniline
aniline, 4-bromo-3-methyl-
SCHEMBL114855
(4-Bromo-3-methylphenyl)amine
4-Bromo-3-methylaniline, 97%
STL169146
AKOS000119547
AC-3718
CS-W007472
PS-3030
BP-10165
DB-023646
B1990
NS00036831
EN300-19933
A19787
O11182
F2190-0485
Z104476134