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4-bromoaniline

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Identification
Molecular formula
C6H6BrN
CAS number
106-40-1
IUPAC name
4-bromoaniline
State
State
At room temperature, 4-bromoaniline is in a solid state. It has a tendency to sublimate under appropriate conditions.
Melting point (Celsius)
63.00
Melting point (Kelvin)
336.00
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.00
General information
Molecular weight
172.02g/mol
Molar mass
172.0040g/mol
Density
1.6150g/cm3
Appearence

4-Bromoaniline is a white to off-white crystalline solid. It may appear as yellowish when impurities are present. The compound is known for being used in the synthesis of various dyes and chemicals.

Comment on solubility

Solubility of 4-Bromoaniline

4-bromoaniline, with the chemical formula C6H6BrN, exhibits interesting solubility characteristics due to its molecular structure.

Generally, 4-bromoaniline is considered to be:

  • Moderately soluble in water: The presence of the amino group (-NH2) enhances its ability to interact with water molecules through hydrogen bonding.
  • Highly soluble in organic solvents: It demonstrates a greater affinity for non-polar solvents, such as chloroform and ethanol, owing to its hydrophobic bromo group.

In practical applications, the solubility of 4-bromoaniline can be influenced by various factors, such as:

  1. Temperature: Higher temperatures often increase solubility in both water and organic solvents.
  2. pH levels: The solubility can change depending on the acidity or basicity of the solution, impacting the ionization of the amino group.

As a result, when working with 4-bromoaniline, it is essential to consider these factors for optimal solubility and reactivity in chemical processes.

Interesting facts

Interesting Facts About 4-Bromoaniline

4-Bromoaniline is a fascinating compound that belongs to the family of aromatic amines. As a derivative of aniline with a bromine substituent in the para position, it has gained significant attention in various fields of study.

Key Properties and Applications

  • Intermediate in Synthesis: 4-Bromoaniline serves as an important intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes. Its reactivity allows for subsequent transformations that are essential in drug development.
  • Research Potential: This compound is widely studied in organic chemistry research. It provides an excellent platform for exploring nucleophilic aromatic substitution reactions, making it a valuable model for students and researchers alike.
  • Biological Activities: Some studies have indicated that derivatives of 4-bromoaniline exhibit interesting biological properties, such as antibacterial and antitumor activities. This potential makes it of interest in medicinal chemistry.
  • Color Production: Due to its azo dye formation capability, 4-bromoaniline is utilized in the dye industry, contributing to color production in textiles and other materials.

Environmental Considerations

While 4-bromoaniline has practical applications, it is essential to consider its environmental impact. Precautionary measures must be taken when handling this compound, as some brominated compounds can have detrimental effects on aquatic life and ecosystems. Researchers are actively investigating methods to mitigate these risks.

Noteworthy Quotes

As noted by a prominent chemist, "Understanding the properties of compounds like 4-bromoaniline not only advances our knowledge but also opens doors to innovative solutions in both industry and healthcare."

In conclusion, 4-bromoaniline is a compound of considerable interest that embodies the intersection of chemistry and real-world applications. Its versatility and potential for further research make it a captivating subject for chemists and students alike.

Synonyms
4-Bromoaniline
106-40-1
P-BROMOANILINE
Benzenamine, 4-bromo-
4-Bromobenzenamine
p-Bromophenylamine
Aniline, p-bromo-
4-Bromo-aniline
4-Bromobenzeneamine
4-Bromanilinu
4-Bromo-phenylamine
4-Bromanilinu [Czech]
CCRIS 4591
HSDB 2194
Aniline, p-bromo
NSC 7085
EINECS 203-393-9
MFCD00007822
UNII-0RR61TC330
BRN 0742031
DTXSID7021867
AI3-17277
ANILINE,4-BROMO
4-Bromoaniline, 97%
NSC-7085
BROMOANILINE, P-
P-BROMOANILINE [MI]
4-BROMOANILINE [HSDB]
DTXCID301867
0RR61TC330
4-12-00-01497 (Beilstein Handbook Reference)
aniline, 4-bromo-
4-BROMANILINU (CZECH)
p-bromo aniline
4-bromophenylamine
CAS-106-40-1
pBromoaniline
4bromoaniline
parabromoaniline
4-brornoaniline
4Bromanilinu
p-bromo-aniline
pBromophenylamine
Aniline, pbromo
4bromobenzenamine
para-bromoaniline
4-bromo aniline
4Bromobenzeneamine
4-aminobromobenzene
R4 4-bromoaniline
Benzenamine, 4bromo
4-bromo-phenyl-amine
(4-bromophenyl)-amine
P-AMINOBROMOBENZENE
SCHEMBL45481
MLS002454431
BIDD:GT0258
CHEMBL57376
4-BROMOANILINE (9CI)
1-AMINO-4-BROMOBENZENE
NSC7085
HMS3050B09
STR00728
Tox21_202459
Tox21_302910
STK286019
4-Bromoaniline, >=99.0% (GC)
4-Bromoaniline, for synthesis, 98%
4-Bromobenzenamine; p-bromophenylamine
AKOS000119091
PS-3352
NCGC00091730-01
NCGC00091730-02
NCGC00256346-01
NCGC00260008-01
AC-13468
SMR001252237
DB-023686
B1393
NS00021481
EN300-19060
D95300
AC-907/25014110
Q412773
F2190-0431