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4-Bromobenzoic acid

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Identification
Molecular formula
C7H5BrO2
CAS number
586-76-5
IUPAC name
4-bromobenzoic acid
State
State
4-Bromobenzoic acid is typically in a solid state at room temperature. It forms crystals and retains a solid structure until it is heated to its melting point.
Melting point (Celsius)
253.00
Melting point (Kelvin)
526.10
Boiling point (Celsius)
295.40
Boiling point (Kelvin)
568.50
General information
Molecular weight
201.02g/mol
Molar mass
201.0230g/mol
Density
1.6640g/cm3
Appearence

4-Bromobenzoic acid appears as a white crystalline solid. It is known for its distinct crystalline structure and is usually encountered in solid form.

Comment on solubility

Solubility of 4-Bromobenzoic Acid

The solubility of 4-bromobenzoic acid, with the chemical formula C7H6BrO2, presents interesting characteristics that are pivotal in various applications in chemical processes.

In aqueous solutions, this compound showcases limited solubility due to the presence of the relatively non-polar bromine substituent, which hinders extensive interactions with water molecules. However, it is significantly more soluble in organic solvents, making it a valuable compound for synthetic chemistry. Below are some key points regarding its solubility:

  • Aqueous Solubility: Generally low; approximately 0.37 g/L at room temperature.
  • Organic Solvent Solubility: Highly soluble in solvents such as ethanol, acetone, and dichloromethane.
  • Temperature Effect: Solubility increases with temperature, which is common among many organic acids.

As a result, when working with 4-bromobenzoic acid, chemists must consider the solvent environment to maximize its effectiveness in reactions. Understanding its solubility properties allows for better predictions in reaction conditions and product formation. Remember, "the solvent choice can often dictate the success of the chemical transformation." Thus, effective solubilization strategies are essential for utilizing this compound in laboratory and industrial settings.

Interesting facts

Interesting Facts about 4-Bromobenzoic Acid

4-Bromobenzoic acid, known for its distinctive bromine substituent at the para position of the benzoic acid structure, is a fascinating compound with various applications in both academic research and industry.

Key Features

  • Versatile Intermediate: This compound is widely used as an intermediate in the synthesis of pharmaceuticals and agrochemicals.
  • Reactivity: The presence of the bromine atom enhances its reactivity in electrophilic aromatic substitution reactions, making it a valuable building block for developing more complex molecules.
  • Crystallization: 4-Bromobenzoic acid can form well-defined crystals, which makes it an excellent candidate for studying crystal structures and intermolecular interactions.

Applications in Research

This compound also serves an important role in various research fields:

  • Analytical Chemistry: It is often used as a reagent in chromatographic techniques for the separation and identification of other compounds.
  • Material Science: Research is ongoing into its use in polymer synthesis, which can lead to the development of new materials with unique properties.
  • Biological Studies: The compound's interaction with biological systems is of interest, as it may exhibit antimicrobial properties, contributing to the search for new antibacterial agents.

Historical Context

The study of 4-bromobenzoic acid dates back to early organic chemistry, where it has been utilized in various synthesis reactions. As one of the building blocks in the chemistry toolkit, it represents the evolution of chemical synthesis techniques.

In conclusion, 4-bromobenzoic acid exemplifies the intersection of traditional chemistry and modern applications, making it a compound worth studying and understanding.

Synonyms
4-Bromobenzoic acid
586-76-5
P-BROMOBENZOIC ACID
Benzoic acid, 4-bromo-
p-Carboxybromobenzene
p-Bromobenzenecarboxylic acid
Benzoic acid, p-bromo-
4-Brom-benzoesaeure
4-carboxybromobenzene
EINECS 209-581-7
4-bromobenzenecarboxylic acid
NSC 17582
BRN 1906923
CHEBI:60698
AI3-08859
NSC-17582
BROMOBENZOIC ACID, P-
6992P6102O
DTXSID7060413
4-BROMOBENZOIC ACID [MI]
4-09-00-01017 (Beilstein Handbook Reference)
NSC-143357
NSC-176126
4bromobenzoic acid
pCarboxybromobenzene
Benzoic acid, pbromo
Benzoic acid, 4bromo
pBromobenzenecarboxylic acid
DTXCID6042440
BENZOIC ACID, 4-BROMO-(9CI)
209-581-7
4-Bromo-benzoic acid
MFCD00002529
4-Bromobenzoicacid
4-Bromobenzoic aicd
Para Bromo Benzoic Acid
UNII-6992P6102O
Z82
4-BrombenZoic acid
4Bromo-benzoic acid
4-brom-benzoic acid
4- bromobenzoic acid
4-Bromo benzoic acid
4-Bromobenzoic acid (1)
4-Bromophenylcarboxylic acid
4-Bromobenzoic acid, 98%
SCHEMBL71380
CHEMBL22051
BDBM239163
NSC17582
STR02440
MFCD06658868
STK301567
AKOS000118916
CS-W020100
FB00905
PS-5301
NCGC00340397-01
BP-31040
HY-78700
PD210226
SY001067
SY345159
DB-016057
B0553
NS00003077
EN300-18038
AB00376738-03
AE-641/00396064
4-Bromobenzoic acid, Vetec(TM) reagent grade, 98%
Q18472729
Z57127530
F2191-0080
InChI=1/C7H5BrO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10
ZR0