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4-(Bromomethyl)benzoic acid

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Identification
Molecular formula
C8H7BrO2
CAS number
619-44-3
IUPAC name
4-(bromomethyl)benzoic acid
State
State

At room temperature, 4-(bromomethyl)benzoic acid is typically in a solid state as a crystalline powder. This state is stable under standard laboratory conditions.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
281.00
Boiling point (Kelvin)
554.15
General information
Molecular weight
215.05g/mol
Molar mass
215.0450g/mol
Density
1.5745g/cm3
Appearence

4-(Bromomethyl)benzoic acid appears as a white to off-white crystalline powder. It is generally solid at room temperature and may have a faint odor. Its crystals can be somewhat shiny or dull depending on the specific sample and conditions.

Comment on solubility

Solubility of 4-(bromomethyl)benzoic acid

4-(Bromomethyl)benzoic acid, with the chemical formula C8H9BrO2, exhibits interesting solubility characteristics that can significantly influence its applications in various fields, particularly in organic synthesis and pharmaceuticals.

Solubility Overview:

  • Water Solubility: This compound is generally moderately soluble in water. The presence of the carboxylic acid group (-COOH) enhances polarity, aiding in water interactions.
  • Solvent Compatibility: It is more readily soluble in organic solvents such as methanol, ethanol, and acetone. The presence of the bromomethyl group adds lipophilic character that often promotes solubility in non-polar to moderately polar solvents.
  • pH Dependence: The solubility can be affected by the pH of the solution. In acidic conditions, the carboxylic acid remains protonated, which can limit solubility; however, at higher pH values, it can deprotonate, increasing solubility due to the formation of carboxylate ions.

The ability of 4-(bromomethyl)benzoic acid to dissolve in various solvents makes it a versatile compound in chemical processes. Understanding its solubility properties is crucial for effective formulation in applications such as:

  1. Organic reactions
  2. Pharmaceutical formulations
  3. Polymer chemistry

To summarize, the solubility of 4-(bromomethyl)benzoic acid is influenced by both its molecular structure and external conditions. This makes it important to consider specific solvent choices and environmental factors during its use.

Interesting facts

Interesting Facts about 4-(Bromomethyl)benzoic Acid

4-(Bromomethyl)benzoic acid is a fascinating compound widely studied in organic chemistry due to its unique structural features and chemical reactivity. Here are some key points to consider:

  • Diverse Applications: This compound is important in the synthesis of polyfunctionalized compounds that find applications in pharmaceuticals, agrochemicals, and material science.
  • Reactivity: The presence of both the bromomethyl and carboxylic acid functional groups makes it an excellent candidate for nucleophilic substitutions and electrophilic aromatic substitutions.
  • Building Block: 4-(Bromomethyl)benzoic acid serves as a versatile building block in organic synthesis, allowing chemists to create more complex molecules efficiently.
  • Structure-Activity Relationship: Researchers often explore the relationship between the structure of this compound and its biological activity, providing insights into the mechanisms of action of various drugs.
  • Environmental Impact: The compound's derivatives can also be studied for their environmental behavior, enhancing our understanding of their ecological footprint.

In summary, 4-(Bromomethyl)benzoic acid is not just a simple chemical entity; it is a critical player in advancing synthetic organic chemistry and the development of new materials and therapeutic agents. Understanding its properties and reactions paves the way for innovations in various scientific disciplines.

Synonyms
4-(BROMOMETHYL)BENZOIC ACID
6232-88-8
4-Bromomethylbenzoic acid
Benzoic acid, 4-(bromomethyl)-
p-Carboxybenzyl bromide
EINECS 228-343-3
NSC 56891
.alpha.-Bromo-para-toluic acid
DTXSID7064154
alpha-Bromo-para-toluic acid
DTXCID3043316
cqqsqbrpajstfb-uhfffaoysa-n
alpha-Bromo-p-toluic acid
p-(Bromomethyl)benzoic acid
4-Carboxybenzyl bromide
A-BROMO-P-TOLUIC ACID
4-Bromomethyl-benzoic acid
.alpha.-Bromo-p-toluic acid
4-(bromomethyl) benzoic acid
p-Toluic acid, .alpha.-bromo-
4-Bromomethylbenzoicacid
MFCD00002567
p-Toluic acid, alpha-bromo-
ALPHA-BROMO-P-TOLUYLIC ACID
4-carboxybenzylbromide
p-bromomethylbenzoic acid
p-Bromomethyl benzoic acid
alpha-bromo-4-toluic acid
alpha-bromo-4-toluoic acid
4-(bromomethyl)-benzoic acid
Benzoidacid,4-(bromomethyl)-
SCHEMBL220750
CHEMBL101846
ALBB-017953
CS-B1333
NSC56891
STR04677
4-(Bromomethyl)benzoic acid, 97%
CK2205
NSC-56891
STK318250
AKOS000103789
AC-1221
FB05446
BP-13470
DB-013437
B0845
NS00035009
EN300-09230
Q27454562
F0001-2461