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(4-bromophenyl)urea

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Identification
Molecular formula
C7H7BrN2O
CAS number
701-29-5
IUPAC name
(4-bromophenyl)urea
State
State
At room temperature, (4-bromophenyl)urea is typically in a solid state, presenting as crystalline in nature. It is relatively stable under standard conditions but should be handled with care to avoid decomposition or reaction with incompatible substances.
Melting point (Celsius)
217.00
Melting point (Kelvin)
490.15
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.15
General information
Molecular weight
215.05g/mol
Molar mass
215.0450g/mol
Density
1.7580g/cm3
Appearence

(4-Bromophenyl)urea likely appears as a white to off-white crystalline solid. Its physical appearance might be modified by impurities and processing methods, but as a pure substance, it should exhibit a fairly uniform and consistent crystalline structure.

Comment on solubility

Solubility of (4-bromophenyl)urea

(4-bromophenyl)urea exhibits unique solubility characteristics that can be intriguing for chemists. To understand its solubility, several factors must be considered:

  • Polarity: The presence of both the urea functional group and the bromophenyl ring influences the overall polarity of the compound. The >N-H groups contribute to hydrogen bonding, enhancing solubility in polar solvents.
  • Solvent Compatibility: (4-bromophenyl)urea is generally more soluble in polar solvents such as water and ethanol compared to non-polar solvents, due to the ability of the urea moiety to form hydrogen bonds.
  • Functional Groups: The bromine substituent can increase the compound's reactivity, affecting its solubility. In particular, it might enhance solubility by interacting with solvent molecules through dipole interactions.

In summary, the solubility of (4-bromophenyl)urea is largely influenced by its molecular structure and the nature of the solvent used. As a rule of thumb, compounds with polar functional groups tend to be more soluble in polar solvents. Therefore, one can conclude that:

“Like dissolves like.”

Consider exploring various solvent systems to fully understand the solubility behavior of this intriguing compound!

Interesting facts

Interesting Facts about (4-bromophenyl)urea

(4-bromophenyl)urea, a derivative of urea, is a fascinating chemical compound with several noteworthy characteristics that have significant implications in various fields of chemistry and biology.

Chemical Structure

At its core, (4-bromophenyl)urea features a urea backbone connected to a brominated phenyl group. This unique structure imparts some unique properties:

  • Substituent Effects: The presence of the bromine atom in the para position of the phenyl ring alters the electronic properties of the molecule, making it an interesting candidate for further chemical reactions.
  • Hydrogen Bonding: Due to the functional urea group, (4-bromophenyl)urea is capable of forming strong hydrogen bonds, which may enhance its solubility in polar solvents.

Applications

This compound is more than just a theoretical interest; it has practical applications:

  • Pharmaceuticals: Compounds like (4-bromophenyl)urea are often studied for their potential as therapeutic agents, particularly in treating various health conditions.
  • Research Tool: Researchers frequently use derivatives of urea in drug development, making it essential in medicinal chemistry studies.
  • Biological Studies: Its properties can be explored to understand enzyme kinetics and receptor-ligand interactions.

Quote from a Chemist

As noted by prominent chemists, “The beauty of organic chemistry lies in the infinite possibilities of modifying simple frameworks like urea to create compounds with diverse biological activities.” This quote encapsulates the essence of studying (4-bromophenyl)urea and its derivatives.

Conclusion

In summary, (4-bromophenyl)urea stands out not only for its interesting molecular structure but also for its versatile applications in scientific research. As we continue to explore this compound, it holds promise for advancements in medicinal chemistry and our understanding of biological processes.

Synonyms
(4-Bromophenyl)urea
N-(4-bromophenyl)urea
UNII-N4K2D5WZSI
N4K2D5WZSI
Urea, (4-bromophenyl)-
AI3-61301
PFQUUCXMPUNRLA-UHFFFAOYSA-
DTXSID30173337
DTXCID1095828
654-932-3
inchi=1/c7h7brn2o/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4h,(h3,9,10,11)
4-BROMOPHENYLUREA
1967-25-5
1-(4-bromophenyl)urea
P-bromophenylurea
Urea, N-(4-bromophenyl)-
MFCD00025428
R3 4-Bromophenylurea
(4-bromophenyl)-urea
Urea,N-(4-bromophenyl)-
SCHEMBL2755848
STL124161
AKOS000200396
BS-4219
DB-044938
B2834
CS-0147088
NS00067576
EN300-13136
F20475
SR-01000069217
SR-01000069217-1
Q27284546
Z89283357
F6660-3424