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4-Bromopyridine

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Identification
Molecular formula
C5H4BrN
CAS number
1120-87-2
IUPAC name
4-bromopyridine
State
State

At room temperature, 4-Bromopyridine is typically in a solid state. It is usually crystalline in nature.

Melting point (Celsius)
94.00
Melting point (Kelvin)
367.00
Boiling point (Celsius)
188.00
Boiling point (Kelvin)
461.00
General information
Molecular weight
158.00g/mol
Molar mass
158.0170g/mol
Density
1.5800g/cm3
Appearence

4-Bromopyridine appears as a colorless to light yellow crystalline solid. It may also appear in the form of needles or flakes and can sometimes be off-white depending on purity and the presence of impurities.

Comment on solubility

Solubility of 4-Bromopyridine

4-Bromopyridine, with the chemical formula C5H4BrN, exhibits noteworthy solubility characteristics that are influenced by its unique structure. Here are some key points regarding its solubility:

  • Solvent Compatibility: 4-Bromopyridine is known to be soluble in organic solvents such as ethanol and acetone, which play a crucial role in various chemical reactions.
  • Water Solubility: Its solubility in water is relatively low, making it less favorable for aqueous environments. However, limited solubility does not negate its utility in certain applications.
  • Temperature Dependence: The solubility can be affected by temperature; generally, increasing the temperature can enhance the solubility of organic compounds.
  • pH Influence: As a nitrogen-containing heteroaromatic compound, 4-bromopyridine can potentially engage in acid-base reactions, which may alter its solubility profile in varying pH conditions.

In summary, while 4-bromopyridine is readily soluble in many organic solvents, its limited water solubility should be taken into account, especially when considering its use in reactions or formulations. This duality highlights the importance of selecting the appropriate solvent for optimal results.

Interesting facts

Interesting Facts about 4-Bromopyridine

4-Bromopyridine is a fascinating chemical compound with a range of applications in various fields of chemistry and industry. Here are some noteworthy insights:

  • Structural Significance: This compound is a derivative of pyridine, characterized by the presence of a bromine atom at the 4-position. This position is crucial for its reactivity and influence on the compound's properties. The specific orientation of the bromine allows for unique interactions with other molecules.
  • Versatile Reactivity: 4-Bromopyridine is known for its ability to undergo several types of chemical reactions, including nucleophilic substitutions and cross-coupling reactions. This makes it a valuable building block in the synthesis of more complex structures.
  • Pharmaceutical Applications: The compound is often utilized in the synthesis of various pharmaceuticals. Its derivatives can exhibit biological activity, leading to the development of new drug candidates, particularly those targeting central nervous system disorders.
  • Importance in Agrochemicals: This compound serves as a key intermediate in the production of agrochemicals. Its involvement in the formation of herbicides and pesticides highlights its significance in agriculture, where it aids in pest management strategies.
  • Research Potential: Scientists continue to explore the properties and applications of 4-bromopyridine in research settings. Its ability to participate in reactions with a wide range of functional groups opens doors to innovative synthetic pathways.

As a compound that bridges multiple areas of chemistry, 4-bromopyridine exemplifies how simple molecular modifications can lead to significant advancements in both synthetic methodology and applied sciences. Its utility in creating essential chemicals underlines its role as an integral component in the development of modern materials and pharmaceuticals.

Synonyms
4-BROMOPYRIDINE
1120-87-2
Pyridine, 4-bromo-
4-pyridyl bromide
CHEBI:51576
EINECS 214-320-5
DTXSID1061520
DTXCID3033274
214-320-5
bsdgzudfpkiyqg-uhfffaoysa-n
inchi=1/c5h4brn/c6-5-1-3-7-4-2-5/h1-4
4-Bromo-Pyridine
CHEMBL325044
p-bromopyridine
4-bromo pyridine
4-Bromopyridine #
MFCD00234035
SCHEMBL8135
ALBB-031101
BCP21648
CS-M0097
BBL009972
BDBM50622792
STK801371
AKOS000445978
AB05093
SB75320
AS-56635
SY002728
DB-006740
DB-023813
NS00045694
B67449
AC-907/25004363
AC-907/25004367
Q229935
4-bromopyridine pound>>4-Bromopyridinehydrochloride