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phenylbutazone

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Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione
State
State

At room temperature, phenylbutazone is in a solid state, appearing as a powder which is used most commonly in pharmaceutical preparations.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
308.37g/mol
Molar mass
308.3660g/mol
Density
0.9975g/cm3
Appearence

Phenylbutazone appears as a white or off-white crystalline powder. It is typically odorless and has a bitter taste.

Comment on solubility

Solubility of 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione

The compound 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione exhibits an interesting solubility profile that is influenced by its unique structural characteristics. Understanding its solubility can be essential for applications in pharmaceuticals and research. Here are some key points to consider:

  • Polar vs. Non-Polar: Due to the presence of the pyrazolidine ring and the butyl group, the compound demonstrates a moderate level of polarity which affects its solubility in different solvents.
  • Solvent Compatibility: It is generally more soluble in polar solvents such as:
    • Water
    • Alcohols
    • Aqueous solutions
  • Low Solubility in Non-Polar Solvents: Contrarily, its solubility in non-polar solvents is limited. This can be attributed to:
    • A lack of interactions with non-polar molecules
    • The steric hindrance introduced by the bulky butyl group
  • Temperature Effects: Solubility can also vary with temperature, often increasing with rising temperatures, which is a common behavior observed in many organic compounds.

In conclusion, the solubility of 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione is essential for its practical applications, and understanding its solubility characteristics can greatly enhance its utility in various fields. As always, it is recommended to conduct empirical solubility tests to determine the most suitable solvent for specific applications.

Interesting facts

Interesting Facts about 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione

4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione is a fascinating compound that belongs to the class of pyrazolidines, which are five-membered heterocycles containing two nitrogen atoms. Here are some key points about this intriguing compound:

  • Biological Activity: Pyrazolidine derivatives, like 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione, are known for their biological properties. Some studies have indicated potential anti-inflammatory and analgesic effects, making them of interest in medicinal chemistry.
  • Versatile Synthesis: The synthesis of this compound can often involve various functional group transformations and cyclization reactions, showcasing the versatility of organic synthesis techniques.
  • Pharmaceutical Relevance: Its structure allows for modifications that can lead to the development of new pharmaceutical agents. This compound could serve as a lead structure in drug design aimed at treating conditions associated with inflammation.
  • Research Potential: As a compound of interest in organic and medicinal chemistry, 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione offers numerous research opportunities, particularly in understanding its mechanism of action and optimizing its therapeutic efficacy.
  • Structure-Activity Relationship: Investigating the relationship between its molecular structure and biological activity can yield insights that inform the design of more effective compounds with minimal side effects.

As noted in various chemical literature, "the exploration of pyrazolidine derivatives continues to yield promising results in both synthesis and application." Scientists are captivated by the potential of compounds like 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione, as they may pave the way for innovative treatments in modern medicine. This compound exemplifies the exciting interface between chemistry and pharmacology!

Synonyms
SCHEMBL21694442