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Lidocaine

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Identification
Molecular formula
C14H22ClN2O
CAS number
137-58-6
IUPAC name
4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione;2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
State
State

At room temperature, Lidocaine is typically found as a solid in the form of a powder. It is commonly used in solution form for medical applications.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
0.9940g/cm3
Appearence

Lidocaine typically appears as a white, crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione; 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide

The solubility of a compound is an important factor that influences its chemical behavior and applications. For the given compound, while specific solubility data might not be readily available, we can infer several points regarding its solubility characteristics based on its structure:

  • Hydrophobic vs. Hydrophilic: The presence of hydrocarbon chains, such as the butyl and diethylamino groups, typically indicates a hydrophobic nature, which can result in reduced solubility in water.
  • Polar Functional Groups: The inclusion of polar functional groups, like the chlorophenoxy and acetamide moieties, may enhance solubility in polar solvents, suggesting that the compound may be more soluble in organic solvents.
  • Temperature Dependency: As with many chemical compounds, solubility can be temperature-dependent. Increased temperature can often increase solubility in various solvents.

In conclusion, the solubility of this compound is likely to be a balance between its hydrophobic areas and the polar functional groups. Understanding solubility is crucial for predicting its behavior in different mediums and its potential applications in chemical processes.

Interesting facts

Interesting Facts about 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione

The compound 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione is a fascinating example of a pyrazolidine derivative that showcases the diversity of nitrogen-containing heterocycles in organic chemistry. Here are some key points regarding this compound:

  • Heterocyclic Structure: As a member of the pyrazolidine family, this compound features a five-membered ring structure incorporating two nitrogen atoms, which contributes to its unique reactivity and properties.
  • Pharmaceutical Relevance: Compounds like this are often investigated for their potential pharmacological properties, making them subjects of interest in drug discovery and development.
  • Reactivity: The presence of dimethyl groups and a butyl chain can influence the compound's reactivity significantly, leading to interesting interactions in biological systems.
  • Potential Applications: Pyrazolidines are known for various biological activities, including anti-inflammatory and analgesic effects, which foreshadow potential therapeutic avenues.

In summary, the structural intricacies and possible utility in medicinal chemistry make 4-butyl-1,2-dimethyl-pyrazolidine-3,5-dione an exciting compound to study. As researchers explore new synthetic pathways, the practical applications of such compounds may expand, further highlighting their importance in modern science.

Interesting Facts about 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide

2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide represents an intriguing class of compounds known for their diverse applications, especially in the realm of pharmaceuticals. Here are some highlights:

  • Pharmaceutical Significance: This compound is often studied for its potential as a drug candidate due to its ability to interact with biological systems, particularly as it contains both an acetamide and aliphatic amine moiety.
  • Chlorophenyl Group: The chlorophenyl moiety enhances lipophilicity, potentially affecting how the compound interacts with cellular membranes, facilitating better absorption in biological systems.
  • Biological Activity: Compounds of this type can exhibit a wide range of pharmacological effects, making them valuable in therapeutic formulations.
  • Study of Structure-Activity Relationship: Researchers often investigate how modifications to parts of this molecule impact its activity, leading to improvements in efficacy and safety profiles.

In conclusion, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide embodies the complexity and potential of modern medicinal chemistry, making it an exciting subject for both academic research and practical applications in health science.

Synonyms
CHEMBL3833413