4-Chloro-2-nitroaniline | Solubility of Things

Identification

Molecular formula

C₆H₅ClN₂O₂

CAS number

89-63-4

IUPAC name

4-chloro-2-nitro-aniline

State

At room temperature, 4-chloro-2-nitroaniline is a solid. It is commonly found in a crystalline state, characterized by its yellow color.

Melting point (Celsius)

138.00

Melting point (Kelvin)

411.15

Boiling point (Celsius)

350.30

Boiling point (Kelvin)

623.45

General information

Molecular weight

172.57g/mol

Molar mass

172.5680g/mol

Density

1.6750g/cm³

Appearence

4-Chloro-2-nitroaniline appears as a yellow solid. It is typically crystalline in nature and may have a faint odor.

Comment on solubility

Solubility of 4-chloro-2-nitro-aniline

4-chloro-2-nitro-aniline (C₆H₅ClN₂O₂) exhibits some intriguing characteristics regarding its solubility. Generally, the solubility of this compound can be influenced by its molecular structure, including the presence of various functional groups which impact interactions with solvents.

Here are some key points about the solubility of 4-chloro-2-nitro-aniline:

Polar characteristics: The nitro group (-NO₂) and amino group (-NH₂) contribute to the molecule's polarity, leading to better solubility in polar solvents like water, though it’s not highly soluble.
Non-polar solvents: Conversely, 4-chloro-2-nitro-aniline is more soluble in organic solvents such as ethanol and chloroform, where the non-polar regions of the molecule can interact more favorably.
Temperature dependence: Solubility may also vary with temperature; generally, increased temperature can enhance solubility in most solvents.
pH influence: The solubility can be significantly affected by the pH of the solution due to the ionization of the amino group under different conditions.

In summary, the solubility of 4-chloro-2-nitro-aniline is dictated by a balance of polar and non-polar interactions, making it a compound of interest when exploring solvent preferences in chemical applications. The nuances of its solubility offer valuable insights into its behavior in various environments.

Interesting facts

Interesting Facts about 4-Chloro-2-nitro-aniline

4-Chloro-2-nitro-aniline, often abbreviated as 4-Cl-2-NA, is a fascinating compound with a variety of applications and properties that intrigue chemists and researchers alike. Here are some interesting facts:

Chemical Structure: This compound features a benzene ring substituted with a chlorine atom and a nitro group, contributing to its versatile chemical behavior.
Applications: 4-Chloro-2-nitro-aniline is primarily used in the synthesis of dyes and pigments. Its vibrant color contributes significantly to various industrial products, making it valuable in the textile industry.
Pharmaceutical Relevance: Due to its aniline component, this compound plays a role in drug synthesis. Anilines are well-known building blocks in medicinal chemistry, leading to the development of numerous pharmaceutical agents.
In Environmental Chemistry: As a chlorinated compound, 4-chloro-2-nitro-aniline can be studied for its environmental impact, particularly its stability and degradation in ecosystems. Understanding these properties helps in assessing risks associated with its use and disposal.
Structure Activity Relationship (SAR): Chemists often explore the relationship between the compound's structure and its biological activity, which can reveal insights into how slight modifications can enhance or diminish its effectiveness in various applications.

4-Chloro-2-nitro-aniline is not just a chemical entity; it exemplifies the intersection of chemistry with industry, pharmaceuticals, and environmental science. As researchers delve deeper into its properties, additional applications and implications may emerge, making it a compound well worth watching.

Synonyms

4-CHLORO-2-NITROANILINE

89-63-4

2-Nitro-4-chloroaniline

p-Chloro-o-nitroaniline

Benzenamine, 4-chloro-2-nitro-

PCON

Red Salt Nbgl

Aniline, 4-chloro-2-nitro-

Daito Red Base 3GL

Devol Red F

4-Chloro-2-nitrobenzenamine

Devol Red Salt F

Red Base Ciba VI

Red Base Irga VI

Red Salt Ciba VI

Red Salt Irga VI

Red 3G Base

Red 3G Salt

Red 3GS Salt

Red Base 3GL

PCONA

Fast Red 2NC Base

Fast Red 2NC Salt

Fast Red 3GL Base

Fast Red 3GL Salt

Fast Red Base 3JL

Fast Red Salt 3GL

Fast Red Salt 3JL

Daito Red Salt 3GL

Diazo Fast Red 3GL

Azofix Red 3GL Salt

Kayaku Red Salt 3GL

Mitsui Red 3GL Base

Mitsui Red 3GL Salt

Symulon Red 3GL Salt

Naphthanil Red 3G Base

Sanyo Fast Red Salt 3GL

Azoene Fast Red 3GL Base

Azoene Fast Red 3GL Salt

Kayaku Fast Red 3GL Base

Fast Red 3GL Special Base

Fast Red 3GL Special Salt

Fast Red Base 3GL Special

Hiltonil Fast Red 3GL Base

Hiltosal Fast Red 3GL Salt

Naphtoelan Fast Red 3GL Base

Naphtoelan Fast Red 3GL Salt

Shinnippon Fast Red 3GL Base

C.I. Azoic Diazo Component 9

NCI-C60355

C.I. 37040

CI 37040

4-Chloro-2-nitro-phenylamine

Azoic diazo component 9, base

DTXSID4030384

1-amino-2-nitro-4-chlorobenzene

NSC-3546

1929LY233C

Kayaku Red Salt GL

Red Base 3 GL

Azofly Red 3GL Salt

o-nitro-p-chloroaniline

Naptoelan Fast Red 3GL Salt

CCRIS 3110

Benzenamide, 4-chloro-2-nitro-

HSDB 5182

1-Amino-4-chloro-2-nitrobenzene

NSC 3546

EINECS 201-925-4

4-chloro-2-nitro-aniline

BRN 0512436

(4-chloro-2-nitrophenyl)amine

AI3-02918

UNII-1929LY233C

MFCD00007836

WLN: ZR DG BNW

2-Nitro-4-chloro aniline

EC 201-925-4

4-chloro-2-nitro-pheylamine

SCHEMBL131251

CHEMBL166405

DTXCID2010384

4-Chloro-2-nitroaniline, 99%

PBGKNXWGYQPUJK-UHFFFAOYSA-

NSC3546

(4-chloro-2-nitro-phenyl)-amine

CI AZOIC DIAZO COMPONENT 9

STR02491

Tox21_200807

STK301777

AKOS000119119

AT23730

FC00475

CAS-89-63-4

2-NITRO-4-CHLOROANILINE [HSDB]

NCGC00091243-01

NCGC00091243-02

NCGC00258361-01

DB-057150

NS00003462

EN300-19072

4-Chloro-2-nitroaniline;2-Nitro-4-chloroaniline

AE-848/33219050

Q27252057

Z104472588

InChI=1/C6H5ClN2O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,8H2