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4-Chloro-2,5-dimethoxyaniline

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Identification
Molecular formula
C8H10ClNO2
CAS number
15733-35-4
IUPAC name
4-chloro-2,5-dimethoxy-aniline
State
State

At room temperature, 4-Chloro-2,5-dimethoxyaniline is typically in a solid state.

Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
314.60
Boiling point (Kelvin)
587.75
General information
Molecular weight
187.63g/mol
Molar mass
187.6340g/mol
Density
1.2860g/cm3
Appearence

4-Chloro-2,5-dimethoxyaniline appears as an off-white to yellow crystalline solid. Its appearance may vary slightly depending on purity and form.

Comment on solubility

Solubility of 4-chloro-2,5-dimethoxy-aniline

4-chloro-2,5-dimethoxy-aniline, with the chemical formula C10H12ClN1O2, exhibits distinctive solubility characteristics that are influenced by its complex structure.

This compound is recognized for:

  • Moderate solubility in organic solvents: 4-chloro-2,5-dimethoxy-aniline is generally soluble in solvents like ethanol, methanol, and acetone, owing to its hydrophobic aromatic ring and the presence of methoxy groups.
  • Poor solubility in water: The presence of the chlorine atom and the methoxy substituents limits its solubility in polar solvents. As a result, its aqueous solubility is minimal, which is a common trait for many organic compounds.
  • Influence of pH: The solubility can be affected by the pH of the solution, as changes in acidity can affect protonation states and lead to different solubility behaviors. This means that under acidic conditions, the compound may show increased solubility due to protonation effects.

As a general observation, the solubility of 4-chloro-2,5-dimethoxy-aniline can be summarized as:

  • Soluble in polar organic solvents
  • Insoluble or very poorly soluble in water
  • Variable solubility in response to changes in pH

In conclusion, understanding the solubility of 4-chloro-2,5-dimethoxy-aniline is crucial for its applications in synthesis and formulation, as these properties dictate its behavior in various chemical environments.

Interesting facts

Interesting Facts about 4-chloro-2,5-dimethoxy-aniline

4-chloro-2,5-dimethoxy-aniline is a fascinating compound that falls within the class of anilines, which are aromatic amines known for their utility in various chemical applications. Here are some intriguing points about this compound:

  • Versatile Precursor: This compound serves as a versatile precursor in organic synthesis and can be used for the production of dyes, pharmaceuticals, and agrochemicals.
  • Substituent Effects: The presence of chlorine and methoxy groups on the aniline structure influences its reactivity and properties. These substituents can enhance or reduce the compound's electrophilic character, making it a valuable building block in synthetic chemistry.
  • Biological Relevance: Anilines and their derivatives often exhibit biological activity. Some studies suggest that compounds like 4-chloro-2,5-dimethoxy-aniline may possess pharmacological properties worth exploring in drug development.
  • Environmental Impact: Research surrounding chlorinated compounds raises important questions about their degradation and potential effects on ecosystems. Understanding how such compounds behave in the environment is crucial for assessing their safety and impact.
  • Synthetic Pathways: Chemists have developed various synthetic routes to create compounds like 4-chloro-2,5-dimethoxy-aniline, showcasing innovative strategies that highlight the creativity of organic synthesis.

As a reminder, when working with compounds such as 4-chloro-2,5-dimethoxy-aniline, proper safety measures and handling protocols should always be followed. The complexities and functionalities of this compound exemplify the rich tapestry of chemical science, where every molecule has the potential to contribute to advancements in technology and medicine.

Synonyms
4-Chloro-2,5-dimethoxyaniline
2,5-Dimethoxy-4-chloroaniline
Benzenamine, 4-chloro-2,5-dimethoxy-
EINECS 228-782-0
UNII-T659IW8P4S
NSC 60154
(4-Chloro-2,5-dimethoxyphenyl)amine
DMCH cpd
BRN 0880445
T659IW8P4S
DTXSID9040718
NSC-60154
1-Amino-4-chloro-2,5-dimethoxybenzene
DTXCID7020718
YGUFQYGSBVXPMC-UHFFFAOYSA-
EC 228-782-0
4-13-00-02556 (Beilstein Handbook Reference)
4-CHLORO-2,5-DIMETHOXYBENZENAMINE
inchi=1/c8h10clno2/c1-11-7-4-6(10)8(12-2)3-5(7)9/h3-4h,10h2,1-2h3
ygufqygsbvxpmc-uhfffaoysa-n
6358-64-1
ANILINE, 4-CHLORO-2,5-DIMETHOXY-
MFCD00014893
4-chloro-2,5-dimethyoxy aniline
NSC60154
SCHEMBL92067
WLN: 1OR BZ EG DO1
4-Chloro-2,5-dimethyoxyaniline
CHEMBL1901690
4-chloro -2,5-dimethoxyaniline
4-chloro-2,5-di-methoxyaniline
4-chloro-2,5-dimethoxy-aniline
4-chloranyl-2,5-dimethoxy-aniline
GAA35864
4-chloro-2,5-dimethoxy-phenylamine
Tox21_301725
AC8069
STL164359
AKOS000121568
4-Chloro-2,5-dimethoxyaniline, 97%
NCGC00164199-01
NCGC00255528-01
AC-10952
AS-14427
SY049708
CAS-6358-64-1
DB-030799
C1996
NS00008793
EN300-16465
A834426
Q27289721