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Chlorocresol

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Identification
Molecular formula
C7H7ClO
CAS number
59-50-7
IUPAC name
4-chloro-3-methyl-phenol
State
State

At room temperature, chlorocresol is typically found in a solid state. It is often utilized in its crystalline form in various industrial and pharmaceutical applications.

Melting point (Celsius)
64.00
Melting point (Kelvin)
337.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
142.58g/mol
Molar mass
142.5830g/mol
Density
1.3060g/cm3
Appearence

Chlorocresol, or 4-chloro-3-methylphenol, appears as a white or slightly yellow crystalline solid. It is known for its antiseptic properties and is commonly used in disinfectants and preservatives.

Comment on solubility

Solubility of 4-Chloro-3-methyl-phenol

4-Chloro-3-methyl-phenol, represented by the chemical formula C7H7ClO, exhibits interesting solubility characteristics influenced by its molecular structure.

In terms of solubility in various solvents:

  • Water: 4-Chloro-3-methyl-phenol is sparingly soluble in water due to its hydrophobic aromatic ring, which limits its interaction with polar water molecules.
  • Alcohols: It is more soluble in alcohols such as ethanol and methanol, where the hydroxyl group can form hydrogen bonds, enhancing solubility.
  • Organic solvents: The compound dissolves well in a variety of organic solvents like acetone and ether, aligning with its non-polar characteristics.

Overall, its solubility behavior can be summarized in the following key points:

  1. Hydrophobicity: The presence of the chlorine atom and the methyl group contributes to its hydrophobic nature.
  2. Hydrogen Bonding: The hydroxyl (-OH) group enables stronger interactions with polar solvents, enhancing solubility in such media.
  3. Molecular Interactions: Solubility varies significantly based on the solvent, highlighting the importance of solvent-solute interactions.

In conclusion, while 4-chloro-3-methyl-phenol shows limited solubility in water, it is significantly more soluble in alcohols and organic solvents, demonstrating its diverse solubility profile.

Interesting facts

Interesting Facts about 4-Chloro-3-methyl-phenol

4-Chloro-3-methyl-phenol, often referred to as p-chloro-m-cresol, is a fascinating compound belonging to the family of phenolic compounds. Here are some intriguing aspects that highlight its chemical significance:

  • Applications in Antiseptics: This compound is widely utilized in medical antiseptics and disinfectants due to its effective antibacterial properties. It is particularly useful in preventing infection during surgical procedures.
  • Role in Pharmaceuticals: Beyond its antiseptic properties, 4-chloro-3-methyl-phenol serves as an important intermediate in the synthesis of various pharmaceuticals. This illustrates the compound’s versatility and importance in drug development.
  • Preservation: It is also employed in the manufacturing of preservatives, showcasing its ability to inhibit microbial growth in various products. This way, it extends the shelf life of many goods.
  • Environmental Considerations: As with many chlorinated compounds, there are environmental considerations. The persistence of such compounds can raise concerns about toxicity and bioaccumulation, necessitating careful handling and regulation.

In conclusion, 4-chloro-3-methyl-phenol exemplifies the dual nature of chemical compounds, serving both practical applications in health and industry while also presenting challenges in environmental management. Its ability to disinfect and preserve makes it indispensable, yet one must always consider the broader ecological implications of its use.

Synonyms
4-Chloro-3-methylphenol
Chlorocresol
59-50-7
4-Chloro-m-cresol
p-Chloro-m-cresol
Parol
Phenol, 4-chloro-3-methyl-
4-Chloro-3-cresol
Ottafact
Baktol
Baktolan
Candaseptic
Parmetol
Peritonan
Raschit
Aptal
p-Chlorocresol
2-Chloro-5-hydroxytoluene
Rasen-Anicon
Preventol CMK
Raschit K
4-Chloro-5-methylphenol
p-Chlor-m-cresol
PCMC
6-Chloro-3-hydroxytoluene
2-Chloro-hydroxytoluene
Parachlorometacresol
3-METHYL-4-CHLOROPHENOL
Chlorcresolum
Chlorkresolum
Chlorocresolo
Chlorocresolum
Chlorokresolum
Clorocresol
Perol
4-Chloro-3-methyl phenol
Chloro-3-cresol
m-Cresol, 4-chloro-
NSC 4166
Rcra waste number U039
Clorocresolo
Clorocresolo [DCIT]
Clorocresol [Spanish]
Chlorocresolum [Latin]
Caswell No. 185A
para-Chloro-meta-cresol
Clorocresol [INN-Spanish]
Chlorocresolum [INN-Latin]
4-chloro-meta-cresol
CCRIS 1938
CHEBI:34395
HSDB 5198
chloromethylphenol
NSC-4166
4-Chloro-1-hydroxy-3-methylbenzene
EINECS 200-431-6
MFCD00002323
EPA Pesticide Chemical Code 064206
Chlorocresol [USAN:INN:NF]
BRN 1237629
DTXSID4021717
AI3-00075
1-Chloro-2-methyl-4-hydroxybenzene
CHLOROCRESOL [II]
CHLOROCRESOL [MI]
CHLOROCRESOL [INN]
CHLOROCRESOL [HSDB]
CHLOROCRESOL [USAN]
CHLOROCRESOL [MART.]
CHLOROCRESOL [WHO-DD]
CHLOROCRESOL [WHO-IP]
DTXCID601717
36W53O7109
EC 200-431-6
CHLOROCRESOL [EP MONOGRAPH]
CHLOROCRESOLUM [WHO-IP LATIN]
Clorocresol (Spanish)
Chlorocresolum (Latin)
NCGC00091338-01
CHLOROCRESOL (II)
Clorocresol (INN-Spanish)
Chlorocresolum (INN-Latin)
CHLOROCRESOL (MART.)
CHLOROCRESOL (EP MONOGRAPH)
CAS-59-50-7
4-chloro-3-methyl-phenol
RCRA waste no. U039
pChlormcresol
pChlorocresol
pChloromcresol
Lysochlor
RasenAnicon
4Chloromcresol
Chloro3cresol
4Chloro3cresol
UNII-36W53O7109
2Chlorohydroxytoluene
3Methyl4chlorophenol
4Chloro3methylphenol
4Chloro5methylphenol
ATTAFACT
NEOPREDISAN
PARMATOL
Caswell No 185A
2Chloro5hydroxytoluene
6Chloro3hydroxytoluene
Spectrum_000130
2p7a
Phenol, 4chloro3methyl
4-chlor-3-methylphenol
PREVENTO 1 CMK
Chlorocresol (NF/INN)
Spectrum2_000002
Spectrum4_000278
Spectrum5_000705
4-chloro-5-methyl-phenol
WLN: QR DG C
CHLOROCRESOLS, SOLID
CHLOROCRESOLS, LIQUID
SCHEMBL12344
4Chloro1hydroxy3methylbenzene
KBioGR_000776
KBioSS_000590
MLS002152924
BIDD:ER0169
DivK1c_000768
Phenol, 4-chloro-5-methyl-
SPECTRUM1500178
SPBio_000003
CHEMBL1230222
4-Chloro-3-methylphenol, 99%
HMS502G10
KBio1_000768
KBio2_000590
KBio2_003158
KBio2_005726
NSC4166
NINDS_000768
P-CHLORO-M-CRESOL [INCI]
PHENOL,4-CHLORO-3-METHYL
HMS1920O03
HMS2091C14
HMS3652F13
HMS3885P09
Pharmakon1600-01500178
HY-B1284
Tox21_111116
Tox21_201293
Tox21_300054
BDBM50527069
CCG-39979
HSCI1_000352
MSK000719
NSC756680
s4209
STL268900
AKOS000120242
Tox21_111116_1
CS-4678
NSC-756680
Chlorocresol (4-Chloro-3-methylphenol)
IDI1_000768
USEPA/OPP Pesticide Code: 064206
NCGC00091338-02
NCGC00091338-03
NCGC00091338-04
NCGC00091338-06
NCGC00254021-01
NCGC00258845-01
AC-14332
LS-13269
PHENOL,4-CHLORO-3-METHYL (9CI)
SMR001224524
SBI-0051308.P003
1ST000719
4-Chloro-3-methylphenol, analytical standard
NS00006064
SW219289-1
EN300-20372
4-Chloro-3-methylphenol, >=98.0% (HPLC)
D03468
AB00051939_02
AB00051939_03
Q302865
SR-05000002033
4-Chloro-3-methylphenol 100 microg/mL in Methanol
SR-05000002033-1
BRD-K89056082-001-03-6
BRD-K89056082-001-06-9
BRD-K89056082-001-07-7
BRD-K89056082-001-08-5
chlorocresol;4-chloro-m-cresol;4-chloro-3-methylphenol
F0001-1543
Z104477910
200-431-6
215-309-8
43M