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4-Chloro-3-nitrobenzenesulfonyl chloride

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Identification
Molecular formula
C6H3ClNO5S
CAS number
104-29-0
IUPAC name
4-chloro-3-nitro-benzenesulfonyl chloride
State
State

At room temperature, 4-chloro-3-nitrobenzenesulfonyl chloride exists as a solid. It is typically in a stable crystalline form that is suitable for various chemical syntheses and reactions, particularly in the preparation of other aromatic sulfonyl compounds.

Melting point (Celsius)
77.00
Melting point (Kelvin)
350.15
Boiling point (Celsius)
315.50
Boiling point (Kelvin)
588.65
General information
Molecular weight
255.61g/mol
Molar mass
255.0620g/mol
Density
1.6594g/cm3
Appearence

4-Chloro-3-nitrobenzenesulfonyl chloride is typically a yellow crystalline solid. It is known for having a distinct appearance due to its yellow color, which can be attributed to the nitro group present in the structure. The crystalline nature of the compound allows for ease of handling and measurement in laboratory settings.

Comment on solubility

Solubility of 4-chloro-3-nitro-benzenesulfonyl chloride

The solubility of 4-chloro-3-nitro-benzenesulfonyl chloride can be described as follows:

  • In Water: This compound is generally poorly soluble in water. Its aromatic structure and the presence of bulky sulfonyl groups hinder its ability to interact favorably with water molecules.
  • In Organic Solvents: 4-chloro-3-nitro-benzenesulfonyl chloride is more soluble in organic solvents such as ethanol, acetone, and chloroform. This solubility behavior is attributed to its non-polar character and compatibility with organic solvent systems.
  • Influence of Temperature: The solubility can be affected by temperature; typically, an increase in temperature may lead to increased solubility in organic solvents.

In summary, when considering the solubility of 4-chloro-3-nitro-benzenesulfonyl chloride, it is essential to note its limited solubility in water and its enhanced solubility in organic solvents, making it better suited for reactions in non-aqueous environments.

Interesting facts

Interesting Facts about 4-Chloro-3-nitro-benzenesulfonyl chloride

4-Chloro-3-nitro-benzenesulfonyl chloride is a fascinating compound that find its utility across various fields, primarily in organic chemistry and pharmaceuticals. Here are some notable facts:

  • Versatile Reactivity: This compound is known for its ability to participate in diverse chemical reactions, making it valuable in the synthesis of various other compounds.
  • Pharmaceutical Applications: It is often used in the development of drugs. Compounds derived from benzenesulfonyl chlorides have shown potential in medicinal chemistry for creating bioactive molecules.
  • Role as a Sulfonylating Agent: 4-Chloro-3-nitro-benzenesulfonyl chloride acts as a potent sulfonylating agent, introducing sulfonyl (–SO2–) groups into organic molecules. This modification can significantly enhance the pharmacological properties of the resulting compounds.
  • Environmental Considerations: Due to its structure, care must be taken during handling and disposal of this compound, as its chlorinated nature raises environmental and safety concerns.
  • Green Chemistry: With advancements in green chemistry, researchers are exploring more sustainable pathways to utilize this compound, aiming to reduce hazardous byproducts and improve reaction efficiencies.

As a versatile compound, 4-chloro-3-nitro-benzenesulfonyl chloride exemplifies the intersection of chemistry and practical applications, allowing scientists to innovate and expand the horizons of organic synthesis.

Synonyms
97-08-5
4-CHLORO-3-NITROBENZENESULFONYL CHLORIDE
4-Chloro-3-Nitrobenzene-1-Sulfonyl Chloride
Benzenesulfonyl chloride, 4-chloro-3-nitro-
4-Chloro-3-nitrobenzenesulfonylchloride
Yellow Sulfon Chloride
3-Nitro-4-chlorobenzenesulfonyl chloride
4-Chloro-3-nitro benzene sulfonyl chloride
4-Chloro-3-nitrobenzenesulphonyl chloride
EINECS 202-558-2
MFCD00007440
DTXSID2059148
SEWNAJIUKSTYOP-UHFFFAOYSA-
2-Chloro-1-nitrobenzene-5-sulfonyl chloride
3-nitro-4-chlorobenzenesulfonylchloride
SCHEMBL376610
9H74VBH6E8
DTXCID6049018
AKOS000119642
3-nitro 4-chlorobenzenesulfonylchloride
CS-W001161
DS-0534
4-chloro-3-nitrobenzensulfonyl chloride
2-nitrochlorobenzene-4-sulfonyl chloride
3-nitro 4-chlorobenzenesulfonyl chloride
3-nitro-4-chlorobenzenesulphonyl chloride
4-Chloro-3-nitro-benzenesulfonyl chloride
4-Chloro-3-nitro-benzenesulphonyl chloride
4-chloro-3-nitrobenzene sulphonyl chloride
4-chloro-3-nitro -benzenesulfonyl chloride
DB-001494
C1887
NS00040509
4-chloro-3-nitrobenzenesulfonic acid chloride
EN300-17131
4-chloro-3-nitro-benzenesulphonic acid chloride
4-Chloro-3-nitrobenzenesulfonyl chloride, 96%
3-nitro-4-chloro-benzene-sulfonic acid-chloride
Z56889113
F0808-2030