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4-chloro-5-sulfamoyl-2-(tetrahydropyran-2-ylmethylamino)benzoic acid

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Identification
Molecular formula
C14H19ClN2O5S
CAS number
114772-53-1
IUPAC name
4-chloro-5-sulfamoyl-2-(tetrahydropyran-2-ylmethylamino)benzoic acid
State
State

At room temperature, 4-chloro-5-sulfamoyl-2-(tetrahydropyran-2-ylmethylamino)benzoic acid is in a solid-state. It tends to remain stable under typical atmospheric conditions but should be stored away from high heat and moisture to prevent decomposition or reaction.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
362.84g/mol
Molar mass
362.8350g/mol
Density
1.3500g/cm3
Appearence

This compound is typically observed as a crystalline solid. The crystals are often colorless to white, indicating a high purity level in its solid form.

Comment on solubility

Solubility of 4-chloro-5-sulfamoyl-2-(tetrahydropyran-2-ylmethylamino)benzoic acid

The solubility of 4-chloro-5-sulfamoyl-2-(tetrahydropyran-2-ylmethylamino)benzoic acid is an important consideration for its practical applications. As a complex chemical with multiple functional groups, its solubility can be influenced by various factors:

  • Polarity: The presence of polar functional groups may enhance solubility in polar solvents such as water.
  • Temperature: Typically, increased temperature can lead to greater solubility of solids in liquids.
  • pH Levels: In acidic or basic conditions, the ionization state of the compound could change, affecting solubility.
  • Solvent Type: Compatibility with different solvent types (e.g., organic vs. aqueous solvents) plays a significant role.

To summarize, "the solubility of a compound is a delicate balance of its chemical structure and environmental conditions." Understanding these factors can lead to optimizing applications in pharmaceuticals and biochemistry.

Interesting facts

Interesting Facts about 4-chloro-5-sulfamoyl-2-(tetrahydropyran-2-ylmethylamino)benzoic acid

This compound is a fascinating example of how complex organic chemistry can be. It belongs to the class of sulfonamides, which are widely recognized for their antibacterial properties and have significant applications in pharmaceuticals. Here are some engaging facts about this compound:

  • Pharmaceutical Importance: Sulfamoyl compounds are pivotal in the development of antibiotics, showcasing their ability to inhibit bacterial growth. This poses remarkable implications for the treatment of infections.
  • Structural Complexity: The presence of the chloro group and the tetrahydropyran moiety enhances the compound's molecular structure, which can influence its interactions within biological systems. Such structure-activity relationships are crucial for medicinal chemistry.
  • Mechanism of Action: Compounds with sulfonamide groups work by mimicking para-aminobenzoic acid (PABA), which is essential for bacterial folate synthesis, effectively blocking the growth of bacteria.
  • Research Potential: The unique configuration of this compound opens the door to studies that explore its efficacy against resistant bacterial strains, contributing to the ongoing battle against antibiotic resistance.
  • Functional Versatility: The tetrahydropyran group may impart various functional properties, making it a topic of interest for synthetic organic chemists looking to develop new drug candidates.

The integration of various functional groups like amino and sulfamoyl not only reflects the innovative nature of synthetic chemistry but also highlights the importance of interdisciplinary approaches in drug discovery. As researchers continue to explore and understand the nuances of such compounds, the potential for novel therapeutic applications is boundless.

To quote a renowned chemist, “The beauty of chemistry lies in the unexpected nature of its compounds and the endless possibilities they yield.” This compound is a testament to that elegance and potential.

Synonyms
18729-06-1
4-Chloro-2-{[(oxan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid
DTXSID40274869