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4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one

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Identification
Molecular formula
C15H16ClNO
CAS number
82287-37-8
IUPAC name
4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one
State
State

The compound is in a solid state at room temperature, typically existing as colorless to light yellow crystals.

Melting point (Celsius)
145.40
Melting point (Kelvin)
418.55
Boiling point (Celsius)
585.70
Boiling point (Kelvin)
858.85
General information
Molecular weight
249.75g/mol
Molar mass
249.7390g/mol
Density
1.3578g/cm3
Appearence

At room temperature, 4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one appears as a crystalline solid. The crystals are typically colorless to light yellow in color.

Comment on solubility

Solubility of 4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one

The solubility of 4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one in various solvents can be somewhat complex due to its unique structure. Here are several key points to consider regarding its solubility:

  • Polar Solvents: This compound tends to have limited solubility in strongly polar solvents like water. Its large, hydrophobic cyclic structure may hinder interactions with water molecules.
  • Non-Polar Solvents: It is more soluble in non-polar solvents such as hydrocarbons (e.g., hexane, toluene), which can better accommodate the hydrophobic portions of the molecule.
  • Effect of Temperature: The solubility may increase with temperature, as heat generally enhances solubility in organic solvents.
  • pH Influence: The solubility could also be affected by the pH of the solvent, given that the aromatic rings and functional groups may interact differently in acidic or basic conditions.

In general, when working with 4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one, it is advisable to test its solubility in various solvents to determine the most effective conditions for your specific application. Its solubility profile highlights the importance of considering both the chemical environment and the molecular characteristics.

Interesting facts

Interesting Facts about 4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one

4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one is a fascinating compound with unique structural and chemical properties that make it a subject of interest among chemists. Here are some intriguing aspects:

  • Structural Complexity: This compound belongs to the class of quinoline derivatives, characterized by a fused bicyclic structure. Its intricate arrangement contributes to its distinct chemical behavior.
  • Biological Activity: Many quinoline derivatives have displayed promising pharmacological properties. They are often explored for their potential use as anticancer, antimicrobial, and anti-inflammatory agents.
  • Chirality: The presence of multiple stereocenters in this compound opens up possibilities for the existence of enantiomers, making it an interesting candidate for studying stereochemistry and its effects on biological activity.
  • Research Applications: The unique structure of this compound may make it useful in the development of new materials, such as organic semiconductors and sensors, due to its electronic properties.
  • Citing Literature: Research into quinoline derivatives, including structures like 4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one, has been documented in numerous publications, highlighting advances in synthetic methodologies and potential applications.

Due to its specific attributes and potential applications in medicinal chemistry and materials science, compounds like 4-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinolin-11-one continue to captivate the interest of researchers worldwide. Its study not only enriches our understanding of organic compounds but also paves the way for future innovations in pharmaceuticals and other fields.

Synonyms
5778-55-2
BRN 1533782
11H-CYCLOHEPTA(b)QUINOLIN-11-ONE, 5,6,7,8,9,10-HEXAHYDRO-4-CHLORO-
4-Chloro-5,6,7,8,9,10-hexahydro-11H-cyclohepta(b)quinolin-11-one
DTXSID60206465
DTXCID60128956
AKOS006215771